A review of chitosan-based multifunctional nanocomposites for drug/gene/protein delivery and gene therapy in cancer treatments: Promises, challenges and outlooks

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 141394 - 141394

Опубликована: Фев. 1, 2025

Язык: Английский

Antibacterial, Stretchable, and Self‐Adhesive Laponite‐TA Based Conductive Hydrogel Sensor for Human Motion Detection

Journal of Applied Polymer Science, Год журнала: 2025, Номер unknown

Опубликована: Фев. 9, 2025

ABSTRACT Due to their biocompatibility and tissue‐like properties, hydrogels have garnered considerable interest in bioelectronics field. Nevertheless, practical implementation is limited by factors such as inadequate mechanical strength, weak interface adhesion, the lack of antimicrobial properties. To address these challenges, a novel conductive hydrogel was synthesized through free radical polymerization, incorporating laponite (LA), tannic acid (TA), polyacrylic (PAA), polyacrylamide (pAAm). An innovative approach employed enhance LA's dispersion ionic liquid (IL) water electrostatic interactions. The integration TA, PAA, PAAm with LA sheets via multiple hydrogen bonds resulted excellent resulting P(AAm‐AA)/IL‐LA/TA exhibits impressive characteristics, including fracture stress 0.44 MPa, strain 1800%. Notably, hydrogel's TA component strong antibacterial activity against Staphylococcus aureus Escherichia coli . This advanced sensor effectively monitors human movements, displaying gauge factor 12.7. Furthermore, its versatile nature facilitates adhesion wide range substrates, making it promising candidate for applications monitoring, electronic devices, medical health surveillance.

Язык: Английский

Tripolyphosphate-crosslinked chitosan-based nanoparticles as pH responsive for curcumin release

Polymer Bulletin, Год журнала: 2024, Номер unknown

Опубликована: Дек. 16, 2024

Язык: Английский