Natural anticancer agents: prospection of medicinal and aromatic plants in modern chemoprevention and chemotherapy

Natural Products and Bioprospecting, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 21, 2025

Abstract Natural products obtained from medicinal and aromatic plants are increasingly recognized as promising anticancer agents due to their structural richness, including terpene flavonoid molecules, which induce apoptosis modulate gene expression. These compounds offer an alternative conventional treatments, often costly, face challenges such multidrug resistance. This review aims provide a approach effectively control cancer by consolidating significant findings in identifying natural agent development plants. It synthesizes the of comprehensive search academic databases, PubMed Springer, prioritizing articles published peer-reviewed journals that address bioprospecting agents. The addresses activities plant extracts essential oils, were selected for relevance chemoprevention chemotherapy. Compounds successfully used therapy include Docetaxel (an antimitotic agent), Etoposide VP-16 topoisomerase II inhibitor), Topotecan (a I Thymoquinone Reactive Oxygen Species-ROS inducer), Phenethyl isothiocyanate (with multiple mechanisms). highlights Hinokitiol, Mahanine, Hesperetin, Borneol, Carvacrol, Eugenol, Epigallocatechin gallate, Capsaicin demonstrated efficacy against types, breast, cervical, gastric, colorectal, pancreatic, lung, prostate, skin cancer. Finally, it need continued studies identify novel can be modern Graphical

Язык: Английский

Anticancer Effect of Cycas media: Molecular Basis Through Modulation of PI3K/AKT/mTOR Signaling Pathway

Molecules, Год журнала: 2024, Номер 29(21), С. 5013 - 5013

Опубликована: Окт. 23, 2024

Many researchers are focusing on screening the biological activities of plants owing to their safety and possible pharmacological actions. Consequently, we aimed explore antiproliferative cytotoxic properties

Язык: Английский