Energy metabolism in health and diseases

Signal Transduction and Targeted Therapy, Год журнала: 2025, Номер 10(1)

Опубликована: Фев. 18, 2025

Язык: Английский

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Intricating connections: the role of ferroptosis in systemic lupus erythematosus

Frontiers in Immunology, Год журнала: 2025, Номер 16

Опубликована: Фев. 4, 2025

Systemic lupus erythematosus (SLE) is a chronic inflammatory and autoimmune disease with multiple tissue damage. However, the pathology remains elusive, effective treatments are lacking. Multiple types of programmed cell death (PCD) implicated in SLE progression have recently been identified. Although ferroptosis, an iron-dependent form death, has numerous pathophysiological features similar to those SLE, such as intracellular iron accumulation, mitochondrial dysfunction, lipid metabolism disorders concentration damage associated-molecular patterns (DAMPs), only few reports demonstrated that ferroptosis involved role pathogenesis continues be neglected. Therefore, this review elucidates potential intricate relationship between provide reliable theoretical basis for further research on SLE.

Язык: Английский

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Study on the Mechanism of Jieduquyuziyin prescription Improving the Condition of MRL/lpr Mice by Regulating T Cell Metabolic Reprogramming through the AMPK/mTOR Pathway

Journal of Ethnopharmacology, Год журнала: 2025, Номер 345, С. 119584 - 119584

Опубликована: Март 3, 2025

Язык: Английский

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Mitochondria dysfunction: A trigger for cardiovascular diseases in systemic lupus erythematosus

International Immunopharmacology, Год журнала: 2024, Номер 144, С. 113722 - 113722

Опубликована: Дек. 1, 2024

Язык: Английский

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