Association of the Red blood cell distribution width with Osteoarthritis Risk: A Cross-sectional Study from NHANES 2009-2018
Research Square (Research Square),
Год журнала:
2025,
Номер
unknown
Опубликована: Май 8, 2025
Abstract
Background：Red
blood
cell
distribution
width
(RDW)
is
considered
a
novel
prognostic
biomarker;
however,
the
correlation
between
RDW
and
osteoarthritis
(OA)
has
not
been
clearly
revealed.
Therefore,
this
study
used
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
2009
to
2018
explore
potential
relationship
OA
in
depth.
Methods：This
cohort
included
13,700
eligible
participants
with
valid
2009-2018.
Logistic
regression
was
OA,
followed
by
subgroup
analysis
verify
results.
The
accuracy
of
compared
BMI
assessed
plotting
receiver
operating
characteristic
(ROC)
curve.
Additionally,
restricted
cubic
spline
(RCS)
evaluate
nonlinear
two.
Results：This
involved
participants.
According
our
findings,
positively
correlated
an
increased
risk
OA,this
positive
persists
even
after
adjusting
for
all
covariates.Subgroup
showed
that
prevalence
persisted
across
groups
different
characteristics,
confirming
its
validity
populations.
results
indicated
had
higher
levels
non-OA
revealed
significant
(P-nonlinear
<
0.05).
ROC
curve
analysis,
superior
predictor
BMI.
Conclusion:
Our
found
are
associated
OA.
Язык: Английский
Celastrol Attenuates Ferroptosis-Mediated Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury via Hippo-YAP Signaling
Phytomedicine,
Год журнала:
2025,
Номер
143, С. 156865 - 156865
Опубликована: Май 17, 2025
Язык: Английский