Potential of Chitosan/Gelatin-Based Nanofibers in Delivering Drugs for the Management of Varied Complications: A Review
Polymers,
Год журнала:
2025,
Номер
17(4), С. 435 - 435
Опубликована: Фев. 7, 2025
Drug
delivery
systems
have
revolutionized
traditional
drug
administration
methods
by
addressing
various
challenges,
such
as
enhancing
solubility,
prolonging
effectiveness,
minimizing
adverse
effects,
and
preserving
potency.
Nanotechnology-based
systems,
particularly
nanoparticles
(NPs)
nanofibers
(NFs),
emerged
promising
solutions
for
biomedicine
delivery.
NFs,
with
their
ability
to
mimic
the
porous
fibrous
structures
of
biological
tissues,
garnered
significant
interest
in
drug-delivering
applications.
Biopolymers
gelatin
(Ge)
chitosan
(CH)
gained
much
more
attention
due
biocompatibility,
biodegradability,
versatility
biomedical
CH
exhibits
exceptional
anti-bacterial
activity,
wound
healing
capabilities,
whereas
Ge
provides
good
biocompatibility
cell
adhesion
properties.
Ge/CH-based
NFs
stimulate
cellular
connections
facilitate
tissue
regeneration
owing
structural
resemblance
extracellular
matrix.
This
review
explores
additive
preparation,
including
electrospinning,
force
pinning,
template
synthesis,
focusing
on
electrospinning
factors
influencing
fiber
structure.
The
properties
CH,
role
release,
formulation
strategies,
characterization
techniques
electrospun
fibers
are
discussed.
Furthermore,
this
addresses
applications
delivering
active
moieties
management
orthopedics
regulatory
considerations,
along
challenges
related
them.
Thus,
aims
provide
a
comprehensive
overview
potential
Язык: Английский
Recent Advances in 4D‐Printed Shape Memory Actuators
Macromolecular Rapid Communications,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 27, 2025
Abstract
4D
printing,
which
combines
the
design
freedom
of
3D
printing
with
responsiveness
smart
materials,
is
revolutionizing
creation
active
structures.
These
structures
can
change
shape
in
response
to
external
stimuli,
paving
way
for
advancements
robotics,
biomedicine,
and
beyond.
However,
a
comprehensive
review
article
highlighting
recent
printed
memory
actuators
(SMAAs)
lacking.
This
explores
exciting
potential
intelligent
SMAAs.
It
examines
concept
materials
used,
like
shape‐memory
polymers
(SMPs),
alloys
(SMAs),
polymer
composites
(SMPCs).
then
dives
into
compatible
techniques
principles
achieving
programmed
changes.
Different
categories
SMAAs
are
explored,
showcasing
their
applications
diverse
fields.
The
concludes
by
discussing
challenges
future
directions,
emphasizing
massive
creating
next
generation
actuators,
making
it
valuable
resource
researchers
field.
Язык: Английский