Most
species
belong
to
ecological
communities
where
their
interactions
give
rise
emergent
community-level
properties,
such
as
diversity
and
productivity.
Understanding
predicting
how
these
properties
change
over
time
has
been
a
major
goal
in
ecology,
with
important
practical
implications
for
sustainability
human
health.
Less
attention
paid
the
fact
that
can
also
because
member
evolve.
Yet,
our
ability
predict
long-term
eco-evolutionary
dynamics
hinges
on
repeatably
result
of
evolution.
Here,
we
review
studies
evolution
both
natural
experimental
make
case
at
least
sometimes
evolve
repeatably.
We
discuss
challenges
faced
investigations
evolutionary
repeatability.
In
particular,
only
handful
enable
us
quantify
argue
quantifying
repeatability
community
level
is
critical
approaching
what
see
three
open
questions
field:
(1)
Is
observed
degree
surprising?
(2)
How
related
traits
species?
(3)
What
factors
affect
repeatability?
outline
some
theoretical
empirical
approaches
addressing
questions.
Advances
directions
will
not
enrich
basic
understanding
ecology
but
help
dynamics.
Microbial Cell Factories,
Год журнала:
2023,
Номер
22(1)
Опубликована: Ноя. 4, 2023
Abstract
Many
plants
possess
immense
pharmacological
properties
because
of
the
presence
various
therapeutic
bioactive
secondary
metabolites
that
are
great
importance
in
many
pharmaceutical
industries.
Therefore,
to
strike
a
balance
between
meeting
industry
demands
and
conserving
natural
habitats,
medicinal
being
cultivated
on
large
scale.
However,
enhance
yield
simultaneously
manage
pest
infestations,
agrochemicals
routinely
used
have
detrimental
impact
whole
ecosystem,
ranging
from
biodiversity
loss
water
pollution,
soil
degradation,
nutrient
imbalance
enormous
health
hazards
both
consumers
agricultural
workers.
To
address
challenges,
biological
eco-friendly
alternatives
looked
upon
with
high
hopes
where
endophytes
pitch
as
key
players
due
their
tight
association
host
plants.
The
intricate
interplay
endophytic
microorganisms
has
emerged
captivating
subject
scientific
investigation,
profound
implications
for
sustainable
biosynthesis
pharmaceutically
important
metabolites.
This
review
delves
into
hidden
world
"secret
wedlock"
endophytes,
elucidating
multifaceted
interactions
underpin
synthesis
compounds
significance
plant
hosts.
Here,
we
briefly
diversity
highlight
potential
role
core
endomicrobiome.
We
also
propose
successful
implementation
situ
microbiome
manipulation
through
high-end
techniques
can
pave
way
towards
more
enriched
future.
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Март 16, 2024
Microbial
interactions
can
lead
to
different
colonization
outcomes
of
exogenous
species,
be
they
pathogenic
or
beneficial
in
nature.
Predicting
the
species
complex
communities
remains
a
fundamental
challenge
microbial
ecology,
mainly
due
our
limited
knowledge
diverse
mechanisms
governing
dynamics.
Here,
we
propose
data-driven
approach
independent
any
dynamics
model
predict
from
baseline
compositions
communities.
We
systematically
validate
this
using
synthetic
data,
finding
that
machine
learning
models
not
only
binary
outcome
but
also
post-invasion
steady-state
abundance
invading
species.
Then
conduct
experiments
for
commensal
gut
bacteria
Enterococcus
faecium
and
Akkermansia
muciniphila
hundreds
human
stool-derived
vitro
communities,
confirming
approaches
experiments.
Furthermore,
find
while
most
resident
are
predicted
have
weak
negative
impact
on
strongly
interacting
could
significantly
alter
outcomes,
e.g.,
faecalis
inhibits
invasion
E.
invasion.
The
presented
results
suggest
powerful
tools
inform
ecology
management
PLoS Computational Biology,
Год журнала:
2023,
Номер
19(1), С. e1010570 - e1010570
Опубликована: Янв. 10, 2023
Assembling
optimal
microbial
communities
is
key
for
various
applications
in
biofuel
production,
agriculture,
and
human
health.
Finding
the
community
challenging
because
number
of
possible
grows
exponentially
with
species,
so
an
exhaustive
search
cannot
be
performed
even
a
dozen
species.
A
heuristic
that
improves
function
by
adding
or
removing
one
species
at
time
more
practical,
but
it
unknown
whether
this
strategy
can
discover
nearly
community.
Using
consumer-resource
models
without
cross-feeding,
we
investigate
how
efficacy
depends
on
distribution
resources,
niche
overlap,
other
aspects
ecology.
We
show
determined
ruggedness
appropriately-defined
ecological
landscape.
identify
specific
measures
are
both
predictive
performance
robust
to
noise
low
sampling
density.
The
feasibility
our
approach
demonstrated
using
experimental
data
from
soil
Overall,
results
establish
conditions
necessary
success
provide
concrete
design
principles
building
high-performing
consortia.
In
microbial
communities,
various
cell
types
often
coexist
by
occupying
distinct
spatial
domains.
What
determines
the
shape
of
interface
between
such
domains—which,
in
turn,
influences
interactions
cells
and
overall
community
function?
Here,
we
address
this
question
developing
a
continuum
model
2D
spatially
structured
with
two
types.
We
find
that,
depending
on
balance
different
proliferation
rates
substrate
friction
coefficients,
domains
is
either
stable
smooth
or
unstable
develops
fingerlike
protrusions.
establish
quantitative
principles
describing
when
these
interfacial
behaviors
arise
good
agreement
both
results
previous
experimental
reports
as
well
new
experiments
performed
here.
Our
work,
thus,
helps
to
provide
biophysical
basis
for
understanding
morphodynamics
proliferating
communities
broader
range
active
systems.
Published
American
Physical
Society
2025
Philosophical Transactions of the Royal Society B Biological Sciences,
Год журнала:
2023,
Номер
378(1877)
Опубликована: Апрель 2, 2023
Most
species
belong
to
ecological
communities
where
their
interactions
give
rise
emergent
community-level
properties,
such
as
diversity
and
productivity.
Understanding
predicting
how
these
properties
change
over
time
has
been
a
major
goal
in
ecology,
with
important
practical
implications
for
sustainability
human
health.
Less
attention
paid
the
fact
that
can
also
because
member
evolve.
Yet,
our
ability
predict
long-term
eco-evolutionary
dynamics
hinges
on
repeatably
result
of
evolution.
Here,
we
review
studies
evolution
both
natural
experimental
make
case
at
least
sometimes
evolve
repeatably.
We
discuss
challenges
faced
investigations
evolutionary
repeatability.
In
particular,
only
handful
enable
us
quantify
argue
quantifying
repeatability
community
level
is
critical
approaching
what
see
three
open
questions
field:
(i)
Is
observed
degree
surprising?
(ii)
How
related
traits
species?
(iii)
What
factors
affect
repeatability?
outline
some
theoretical
empirical
approaches
addressing
questions.
Advances
directions
will
not
enrich
basic
understanding
ecology
but
help
dynamics.
This
article
part
theme
issue
'Interdisciplinary
biology'.
