Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction DOI
Robert J. Shmookler Reis, Srinivas Ayyadevara, Akshatha Ganne

и другие.

Опубликована: Июнь 26, 2024

Numerous factors predispose to progression of cognitive impairment Alzheimer's disease and related dementias (ADRD), most notably age,

Язык: Английский

Mitochondria in aging and age-associated diseases DOI Creative Commons
Sonu Pahal, Nirjal Mainali, Meenakshisundaram Balasubramaniam

и другие.

Mitochondrion, Год журнала: 2025, Номер 82, С. 102022 - 102022

Опубликована: Фев. 27, 2025

Mitochondria, essential for cellular energy, are crucial in neurodegenerative disorders (NDDs) and their age-related progression. This review highlights mitochondrial dynamics, mitovesicles, homeostasis, organelle communication. We examine impacts from aging NDDs, focusing on protein aggregation dysfunction. Prospective therapeutic approaches include enhancing mitophagy, improving respiratory chain function, maintaining calcium lipid balance, using microRNAs, transfer to protect function. These strategies underscore the role of health neuronal survival cognitive functions, offering new opportunities.

Язык: Английский

Процитировано

0
Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction DOI
Robert J. Shmookler Reis, Srinivas Ayyadevara, Akshatha Ganne

и другие.

Опубликована: Июнь 26, 2024

Numerous factors predispose to progression of cognitive impairment Alzheimer's disease and related dementias (ADRD), most notably age,

Язык: Английский

Процитировано

3