Advanced Synthesis & Catalysis, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 18, 2024
Abstract Difuropyridines have been prepared from aldehydes and chitin‐derived 3‐acetamidofuran (3AF) under acid‐catalyzed conditions. were comprehensively synthesized for the first time. The difuropyridines can be applied to prepare fluorescent probe analogs or catalyze decarboxylative reactions as photocatalysts.
Язык: Английский
ChemistryOpen, Год журнала: 2025, Номер unknown
Опубликована: Фев. 25, 2025
Abstract The transformation of chitin and its monomer N‐acetylglucosamine (NAG) to high‐value organonitrogen chemicals has attracted increasing interest, with 3‐acetamido‐5‐acetylfuran (3A5AF) proposed as a versatile platform chemical. preparation 3A5AF from NAG relied on high boiling organic solvents, ionic liquids (ILs) or deep eutectic solvents (DES). While these methods have met some success, the isolation recycling solvent remains problematic for non‐IL whereas most IL utilize inherently expensive aprotic ILs substantial environmental footprints. This study details in more cost‐effective chloride‐based protic (PILs) lower synthetic footprints than conventional ILs. Maximum yields 42.5 %, 51.5 % 57.0 were afforded 1,8‐diazabicyclo[5.4.0]undec‐7‐ene chloride ([DBU]Cl), tripropylammonium ([TPA]Cl) tributylammonium ([TBA]Cl) respectively 2 eq. B(OH) 3 at 150 °C. formed was readily isolated by simple extraction, avoiding column chromatography, selected systems displaying good recyclability scalability. E‐factor calculations revealed that PIL methodology produced substantially less waste approaches production molecular DES, highlighting PILs are suitable sustainable 3A5AF.
Язык: Английский
Процитировано
0
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 161550 - 161550
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Advanced Synthesis & Catalysis, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 1, 2024
Abstract Biomass has been identified as the ultimate sustainable resource for all carbon‐based consumer products of chemical industries in future. Its catalytic conversion leads to formation various platform chemicals that could partially or even fully replace fossil‐based building blocks have currently used synthetic processes. Among these compounds, levulinic acid (LA) recognized a member “Top Value Added Chemicals from Biomass” and attracted significant attention since seminal paper reported by Werpy Petersen 2004. This review summarizes properties, recent advances, developments chemistry acid. The production LA both plant animal‐based carbohydrate feedstocks via 5‐hydroxymethylfurfural furfuryl alcohol is discussed mechanistic perspective, highlighting intrinsic molecular‐level limitations formation. efficiencies recently developed systems are also summarized compared. Furthermore, into high‐value‐added downstream chemicals, including its role synthesis complex molecular structures, overviewed. section reactions points view transformations on carbonyl‐, carboxy‐, methyl‐, methylene functional groups. functionalities with C −, N O S ‐nucleophiles, alcohols, amines, organometallic reagents, oxygen etc. were thematically summarized. Our outlooks highlight challenges opportunities associated extensive research area organic
Язык: Английский
Процитировано
2
Fermentation, Год журнала: 2024, Номер 10(9), С. 488 - 488
Опубликована: Сен. 19, 2024
p-Cymene (p-C) [1-methyl-4-(1-methylethyl)-benzene] is a monoterpene found in variety of plants and has several biological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer properties. This paper explores the microbial fermentation pathways involved biosynthesis p-C, with an emphasis on its potential as therapeutic agent. Through biochemical processes, p-C can be produced using renewable precursors such limonene 1,8-cineole. Recent advances technology have enhanced efficiency production, highlighting role various industries. Additionally, this reviews antimicrobial bioactivity focusing ability to inhibit pathogens modulate immune responses. The integration methods offers sustainable approach producing for applications perfume, cosmetics, food, pharmaceutical sectors. Understanding these biosynthetic crucial advancing use bio-based chemical potential. In particular, inhibits expression cytokine signal 3 intestinal inflammation modulates antioxidant immunomodulatory systems protect barrier cells maintain mucus layer.
Язык: Английский
Процитировано
1
Advanced Synthesis & Catalysis, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 18, 2024
Abstract Difuropyridines have been prepared from aldehydes and chitin‐derived 3‐acetamidofuran (3AF) under acid‐catalyzed conditions. were comprehensively synthesized for the first time. The difuropyridines can be applied to prepare fluorescent probe analogs or catalyze decarboxylative reactions as photocatalysts.
Язык: Английский
Процитировано
0