Neural dynamics in superior colliculus of freely moving mice DOI Creative Commons
Shelby L. Sharp, Jhoseph Shin, Dylan M. Martins

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown

Опубликована: Апрель 19, 2025

Abstract Vision is an active process that depends on head and eye movements to explore the visual environment. Superior colliculus (SC) known for its role in generating these movements, as well processing information, but has not been studied extensively during free movement complex environments. To determine impact of vision, we recorded neural activity across depth SC while simultaneously recording position. We find superficial (sSC) neurons respond input following gaze-shifting saccadic whereas deep (dSC) themselves, demonstrated by their sustained response darkness. Additionally, motor responses dSC are more correlated rather than movements. Furthermore, compared sSC gaze shift primary cortex (V1), finding similarities key types, although temporal sequences shifts differ between regions. Our results demonstrate distinct differences V1 highlighting various roles plays vision. Highlights depths superior freely moving mice measuring Neurons mouse strongly shifts, layers. primarily a movement. generally represent movement, independent input. While share with there unique profiles suggest

Язык: Английский

Neural dynamics in superior colliculus of freely moving mice DOI Creative Commons
Shelby L. Sharp, Jhoseph Shin, Dylan M. Martins

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown

Опубликована: Апрель 19, 2025

Abstract Vision is an active process that depends on head and eye movements to explore the visual environment. Superior colliculus (SC) known for its role in generating these movements, as well processing information, but has not been studied extensively during free movement complex environments. To determine impact of vision, we recorded neural activity across depth SC while simultaneously recording position. We find superficial (sSC) neurons respond input following gaze-shifting saccadic whereas deep (dSC) themselves, demonstrated by their sustained response darkness. Additionally, motor responses dSC are more correlated rather than movements. Furthermore, compared sSC gaze shift primary cortex (V1), finding similarities key types, although temporal sequences shifts differ between regions. Our results demonstrate distinct differences V1 highlighting various roles plays vision. Highlights depths superior freely moving mice measuring Neurons mouse strongly shifts, layers. primarily a movement. generally represent movement, independent input. While share with there unique profiles suggest

Язык: Английский

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