Post-COVID-19 Depressive Symptoms: Epidemiology, Pathophysiology, and Pharmacological Treatment

CNS Drugs, Год журнала: 2022, Номер 36(7), С. 681 - 702

Опубликована: Июнь 21, 2022

Язык: Английский

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Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study

The Lancet Public Health, Год журнала: 2022, Номер 7(5), С. e406 - e416

Опубликована: Март 15, 2022

Summary

Background

Long-term mental and physical health consequences of COVID-19 (long COVID) are a persistent public concern. Little is still known about the long-term non-hospitalised patients with varying illness severities. Our aim was to assess prevalence adverse symptoms among individuals diagnosed in general population by acute infection severity up 16 months after diagnosis.

Methods

This observational follow-up study included seven prospectively planned cohorts across six countries (Denmark, Estonia, Iceland, Norway, Sweden, UK). Participants were recruited from March 27, 2020, Aug 13, 2021. Individuals aged 18 years or older eligible participate. In cross-sectional analysis, we contrasted symptom depression, anxiety, COVID-19-related distress, poor sleep quality (screened validated instruments) without diagnosis at entry, 0–16 cohort further used repeated measures estimate change before

Findings

The analytical consisted 247 249 individuals, 9979 (4·0%) whom during period. Mean 5·65 (SD 4·26). presented overall higher depression (prevalence ratio [PR] 1·18 [95% CI 1·03–1·36]) poorer (1·13 [1·03–1·24]) but not anxiety (0·97 [0·91–1·03]) distress (1·05 [0·93–1·20]) compared Although attenuated time, never bedridden due their consistently lower risk (PR 0·83 0·75–0·91]) (0·77 [0·63–0·94]) than those COVID-19, whereas who for more 7 days persistently 1·61 1·27–2·05]) (1·43 [1·26–1·63]) throughout

Interpretation

Severe illness—indicated extended time bedridden—is associated morbidity recovering population. These findings call increased vigilance development severe disease phase COVID-19.

Funding

Nordforsk, Horizon2020, Wellcome Trust, Estonian Research Council.

Язык: Английский

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ESCMID rapid guidelines for assessment and management of long COVID

Clinical Microbiology and Infection, Год журнала: 2022, Номер 28(7), С. 955 - 972

Опубликована: Фев. 17, 2022

Язык: Английский

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COVID-19 and common mental health symptoms in the early phase of the pandemic: An umbrella review of the evidence

PLoS Medicine, Год журнала: 2023, Номер 20(4), С. e1004206 - e1004206

Опубликована: Апрель 25, 2023

Background There remains uncertainty about the impact of Coronavirus Disease 2019 (COVID-19) pandemic on mental health. This umbrella review provides a comprehensive overview association between and common disorders. We qualitatively summarized evidence from reviews with meta-analyses individual study-data in general population, healthcare workers, specific at-risk populations. Methods findings A systematic search was carried out 5 databases for peer-reviewed prevalence depression, anxiety, post-traumatic stress disorder (PTSD) symptoms during published December 31, until August 12, 2022. identified 123 which 7 provided standardized mean differences (SMDs) either longitudinal pre- to or cross-sectional compared matched pre-pandemic data. Methodological quality rated Assessment Multiple Systematic Reviews checklist scores (AMSTAR 2) instrument generally low moderate. Small but significant increases and/or health were reported people preexisting physical conditions, children (3 reviews; SMDs ranged 0.11 0.28). Mental depression significantly increased periods social restrictions (1 review; 0.41 0.83, respectively) anxiety did not (SMD: 0.26). Increases larger longer-lasting 0.16 0.23) than those (2 reviews: 0.12 0.18). Females showed increase males review: SMD 0.15). In disorders, any patient group, adolescents, students, no found SMD’s ranging −0.16 0.48). 116 pooled rates PTSD 9% 48% across Although heterogeneity studies high largely unexplained, assessment tools cut-offs used, age, sex gender, COVID-19 exposure factors be moderators some reviews. The major limitations are inability quantify explain included shortage within-person data multiple studies. Conclusions small consistent deterioration particularly early has been population chronic somatic Also, associations stronger females younger age groups others. Explanatory individual-level, exposure, time-course scarce inconsistencies For policy research, repeated assessments panels including vulnerable individuals recommended respond current future crises.

Язык: Английский

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S1-Leitlinie Long-/Post-COVID

Pneumologie, Год журнала: 2022, Номер 76(12), С. 855 - 907

Опубликована: Дек. 1, 2022

The German Society of Pneumology initiated 2021 the AWMF S1 guideline Long COVID/Post-COVID. In a broad interdisciplinary approach, this was designed based on current state knowledge.The clinical recommendations describe COVID/Post-COVID symptoms, diagnostic approaches, and therapies.In addition to general consensus introduction, subject-specific approach taken summarize has an explicit practical claim will be developed adapted by author team increase in knowledge.Die Deutsche Gesellschaft für Pneumologie hat die S1-Leitlinie Long-/Post-COVID initiiert. einem breiten interdisziplinären Ansatz wurde diese basierend auf dem aktuellen Wissensstand gestaltet.Die klinische Empfehlung beschreibt Long- bzw. Post-COVID-Symptome, diagnostische Ansätze und Therapien.Neben der allgemeinen konsentierten Einführung ein fachspezifischer Zugang gewählt, den zusammenfasst.Die Leitlinie einen explizit praktischen Anspruch wird Wissenszugewinn vom Autorenteam weiterentwickelt adaptiert.

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Short- and long-term neuropsychiatric outcomes in long COVID in South Korea and Japan

Nature Human Behaviour, Год журнала: 2024, Номер 8(8), С. 1530 - 1544

Опубликована: Июнь 25, 2024

Язык: Английский

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Relationship between Mental Health and Emotional Eating during the COVID-19 Pandemic: A Systematic Review

Nutrients, Год журнала: 2022, Номер 14(19), С. 3989 - 3989

Опубликована: Сен. 26, 2022

Obesity is one of the most dangerous epidemics 21st century. In 2019, COVID-19 pandemic began and caused many deaths among patients with obesity without complications. Simultaneously, lockdown related to a host emotional problems including anxiety, depression, sleep disturbances. Many people cope their emotions by increasing food (emotional eating) alcohol consumption in combination decreased physical activity, promoted development overweight obesity. Emotional eating, also known as stress defined propensity eat response positive negative not need. It should be noted that eating may first step binge disorder its extreme subtypes such addiction. Interestingly some post-bariatric surgery patients, an increased frequency addictive disorders has been observed, for example addiction replaced called: “cross addiction” or “addiction transfer”. This data indicates treated psychosomatic disease, which external factors causing formation play significant role. Currently, these pandemic. manuscript discusses relationships between well potential implications viral on pandemic, need change approach treatment future.

Язык: Английский

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Preliminary Guidelines for the Clinical Evaluation and Management of Long COVID

Infection and Chemotherapy, Год журнала: 2022, Номер 54(3), С. 566 - 566

Опубликована: Янв. 1, 2022

Long-lasting coronavirus disease 2019 (COVID-19) symptoms beyond 12 weeks, the so-called 'long COVID' have been increasingly reported worldwide. Long COVID can be manifested in various forms, and there is an increasing demand for proper assessment management. However, it challenging when trying to determine best-practice standards of care based on current evidence because no internationally agreed clinical definition or clear treatment pathway. Therefore, present guidelines drafted provide advice diagnosis management latest updated available consensus expert opinion. So far, standard test drug strongly recommended patients with long a lack evidence. The key questions, including appropriate interventions that used practice. Continuous careful observation studies related are needed long-term impact COVID-19 determined.

Язык: Английский

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The levels and related factors of mental workload among nurses: A systematic review and meta‐analysis

International Journal of Nursing Practice, Год журнала: 2023, Номер 29(5)

Опубликована: Март 23, 2023

Abstract Aim The aim was to determine the overall levels and related factors of mental workload assessed using NASA‐TLX tool among nurses. Background Mental is a key element that affects nursing performance. However, there exists no review regarding tool, focusing on Design A systematic meta‐analysis. Data Sources PubMed, MEDLINE, Web Science, EMBASE, PsycINFO, Scopus, CINAHL, CNKI, CBM, Weipu WanFang databases were searched from 1 January 1998 30 February 2022. Review Methods Following PRISMA statement recommendations, methods resulted in 31 quantitative studies retained for inclusion which evaluated with evaluation criteria observational as recommended by Agency Healthcare Research Quality. data pooled random‐effects meta‐analysis conducted. Results Findings showed score 65.24, prevalence high 54%. Subgroup analysis indicated nurses developing countries emergency departments experienced higher workloads, workloads front‐line increased significantly during COVID‐19 pandemic. Conclusion These findings highlight experience an urgent need explore interventions decrease their workloads.

Язык: Английский

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Cognitive-behavioral therapy for patients with post-COVID-19 condition (CBT-PCC): a feasibility trial

Psychological Medicine, Год журнала: 2023, Номер 54(6), С. 1122 - 1132

Опубликована: Окт. 16, 2023

Abstract Background The post-COVID-19 condition describes the persistence or onset of somatic symptoms (e.g. fatigue) after acute COVID-19. Based on an existing cognitive-behavioral treatment protocol, we developed a specialized group intervention for individuals with condition. present study examines feasibility, acceptance, and effectiveness program inpatients in neurological rehabilitation setting. Methods comprises eight sessions includes psychoeducational experience-based interventions common psychophysiological mechanisms persistent symptoms. A feasibility trial was conducted using one-group design naturalistic N = 64 history mild COVID-19 that fulfilled WHO criteria were enrolled. After each session, evaluation forms completed psychometric questionnaires psychopathological symptom burden collected pre- post-intervention. Results well received by participants therapists. Each session rated as comprehensible overall satisfaction high. Pre-post effect sizes (of standard incl. new program; intention-to-treat) showed significantly reduced subjective fatigue ( p < 0.05, d av 0.33) improved disease coping ps 0.33–0.49). Conclusions Our results support acceptance newly Yet, findings have to be interpreted cautiously due lack control follow-up measurement, small sample size, relatively high drop-out rate.

Язык: Английский

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