Cancers, Год журнала: 2024, Номер 16(17), С. 2925 - 2925
Опубликована: Авг. 23, 2024
Circadian rhythms dictate the timing of cellular and organismal physiology to maintain homeostasis. Within liver gut, circadian influence lipid glucose homeostasis, xenobiotic metabolism, nutrient absorption. Disruption this orchestrated is known negatively impact human health contribute disease progression, including carcinogenesis. Dysfunctional core clock has been identified in malignant growths may be used as a molecular signature progression. Likewise, its downstream effectors also represent potential for novel therapeutic targets. Here, role pathogenesis cancers gut will reviewed, chronotherapy chronopharmacology explored treatment options.
Язык: Английский