Geneticsbiologiesingle cell and expression analysis for erectile dysfunction and cervical cancer targets DOI Creative Commons

Tengfei Zhao,

Yangyang Li,

Huixue Liu

и другие.

Discover Oncology, Год журнала: 2024, Номер 15(1)

Опубликована: Дек. 21, 2024

Sexual dysfunction and cervical cancer are genetically molecularly two complex health problems. Here, we integrate genetic inference single-cell expression analysis to identify potential targets for sexual cancer, assess causality of these utilizing Mendelian randomization approaches. We performed a genome-wide association study (GWAS) variants associated with cancer. Next, examined the cellular landscape variation regions based on scRNAseq data. The identified several that correlated respectively, differentially expressed in reproductive cells. Two-Gene Combination Panel Increased WISP1 gene was detected tissues. Twas most highly T cells, least well- when cells were proliferating. integrates genetics nominate establishes causal support from approach.

Язык: Английский

Causal relationship between mitochondrial function and delirium: a bidirectional two‐sample Mendelian randomisation analysis DOI Open Access
Yunyang Han, Yu Tian,

Lan-lin Song

и другие.

Psychogeriatrics, Год журнала: 2024, Номер 25(1)

Опубликована: Дек. 10, 2024

Previous studies have suggested a potential link between delirium and mitochondrial function. Consequently, this Mendelian randomisation (MR) study aimed to further investigate their causal relationship.

Язык: Английский

Процитировано

0
Geneticsbiologiesingle cell and expression analysis for erectile dysfunction and cervical cancer targets DOI Creative Commons

Tengfei Zhao,

Yangyang Li,

Huixue Liu

и другие.

Discover Oncology, Год журнала: 2024, Номер 15(1)

Опубликована: Дек. 21, 2024

Sexual dysfunction and cervical cancer are genetically molecularly two complex health problems. Here, we integrate genetic inference single-cell expression analysis to identify potential targets for sexual cancer, assess causality of these utilizing Mendelian randomization approaches. We performed a genome-wide association study (GWAS) variants associated with cancer. Next, examined the cellular landscape variation regions based on scRNAseq data. The identified several that correlated respectively, differentially expressed in reproductive cells. Two-Gene Combination Panel Increased WISP1 gene was detected tissues. Twas most highly T cells, least well- when cells were proliferating. integrates genetics nominate establishes causal support from approach.

Язык: Английский

Процитировано

0