
Experimental Gerontology, Год журнала: 2025, Номер 205, С. 112757 - 112757
Опубликована: Апрель 17, 2025
This study aimed to explore the associations between magnesium depletion score (MDS) and frailty prevalence, as well its prognostic significance for all-cause cardiovascular mortality among US older adults with frailty. We analyzed data from participating in 1999-2018 National Health Nutrition Examination Survey. The primary exposure was MDS, main outcomes were prevalence of defined by 49-item accumulation-deficit model or frail participants. MDS using multivariable-adjusted logistic regression Cox proportional hazards models, respectively. Overall, 13,551 participants (mean age 71.31 years, 45.46 % men, 4464 frailty) included. Compared = 0 group, odds ratio 95 confidence interval (CI) 1.144 (0.899-1.456), 1.702 (1.327-2.183), 2.661 (2.038-3.475) 1, 2, ≥ 3 groups, A total 2195 (791 cardiovascular-related) deaths occurred during a median follow-up 70 months. hazard ratios CIs groups 1.509 (1.146-1.986), 1.988 (1.515-2.611), 2.751 (2.125-3.562), respectively, mortality, 1.376 (0.843-2.246), 1.933 (1.183-3.160), 2.872 (1.817-4.541), respectively mortality. higher is related increased risk adults.
Язык: Английский