Hierarchical Self‐Assembly of Short Peptides: Nanostructure Formation, Function Tailoring, and Applications
Macromolecular Bioscience,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 31, 2025
This
article
explores
the
hierarchical
self-assembly
of
short
peptides,
which
refers
to
structured
spatial
arrangements
these
molecules
over
long
distances.
phenomenon
is
commonly
found
in
nature
and
has
important
implications
for
biological
structure
function.
Short
peptides
are
preferred
because
they
have
ability
spontaneously
create
various
nanostructures.
process,
known
as
bottom-up
assembly,
allows
addition
functional
groups
at
carboxyl
or
amine
ends
peptides.
These
enable
specific
functions
that
extremely
valuable
fields
biotechnology
biomedicine.
text
discusses
basic
processes
involved
such
characteristics
amino
acid
side
chains,
categorization
according
their
chemical
structure,
influence
intermolecular
forces,
dynamic
process.
In
addition,
paper
uses
disciplines
biomedicine
optoelectronics,
including
stimulus-responsive
hydrogels,
tissue
engineering,
drug
delivery.
The
also
suggests
rational
design
principles
controlling
creating
new
commercial
applications,
particularly
with
offers
insights
into
future
discipline.
Язык: Английский
Self‐assembly of Tyrosine Scaffolds in Aqueous Media: Complex Molecular Architectures from Simple Building Blocks
The Chemical Record,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 10, 2025
Abstract
Mimicking
natural
systems,
self‐assembly
has
been
employed
for
constructing
highly
stable
and
well‐ordered
supramolecular
structures.
Amino
acids
are
frequently
used
as
building
blocks
in
the
process
due
to
their
advantageous
characteristics
including
easy
availability,
functionalization,
tunable
mechanical
property,
biodegradability.
In
situ
generation
of
active
obtain
complex
materials
via
enhanced
application
biomedical
fields
bio‐imaging,
therapeutics.
Single
amino
acid
small
building‐block
can
provide
artificial
with
unique
properties.
this
review,
we
summarize
tyrosine‐derivatives
single
acid‐based
providing
assemblies
perspectives
on
potential
impact.
Finally,
discuss
ongoing
challenges
future
research.
Язык: Английский
Nanoscale Spatial Control over the Self-Assembly of Small Molecule Hydrogelators
Gels,
Год журнала:
2025,
Номер
11(4), С. 289 - 289
Опубликована: Апрель 14, 2025
Spatial
control
over
molecular
self-assembly
at
the
nano
scale
offers
great
potential
for
many
high-tech
applications,
yet
remains
a
challenging
task.
Here,
we
report
polymer
brush-mediated
strategy
to
confine
of
hydrazone-based
hydrogelators
exclusively
nanoparticle
surfaces.
The
surfaces
these
nanoparticles
are
grafted
with
negatively
charged
polyacrylic
acid,
which
enrich
protons
that
can
catalyze
in
situ
formation
and
gelators.
We
found
that,
respect
lengths,
concentration
presents
more
significant
effects
on
process
properties
resultant
hydrogels,
including
gelation
time,
stiffness,
network
morphology.
More
interestingly,
hydrogel
fibers
be
formed
specifically
around
nanoparticles,
demonstrating
directed
nanoscale
self-assembly.
This
work
demonstrates
triggering
using
catalysis
serve
as
an
effective
way
realize
scale,
may
powerful
approach
improve
material
properties,
such
mechanical
supramolecular
materials
this
work.
Язык: Английский
Study on the Application of Chitosan-Based Hydrogels in Skin Wound Repair
Advances in Clinical Medicine,
Год журнала:
2025,
Номер
15(05), С. 2402 - 2408
Опубликована: Янв. 1, 2025
Язык: Английский
Low‐molecular‐weight gels from amino acid and peptide derivatives for controlled release and delivery
Journal of Peptide Science,
Год журнала:
2024,
Номер
30(12)
Опубликована: Июль 15, 2024
Low-molecular-weight
(LMW)
gelators
are
a
versatile
class
of
compounds
able
to
self-assemble
and
form
supramolecular
materials,
such
as
gels.
The
use
LMW
peptides
produce
these
gels
shows
many
advantages,
because
their
wide
structure
tunability,
the
low-cost
effective
synthesis,
in
vivo
biocompatibility
biodegradability,
which
makes
them
optimal
candidates
for
release
delivery
applications.
In
addition,
binding
hosts
may
occur
through
variety
noncovalent
interactions,
also
main
factors
responsible
self-assembly
gelators,
specific
interactions
with
fibers
or
pores
gel
matrix.
This
review
aims
report
based
on
amino
acid
peptide
derivatives
used
different
species
(drugs,
fragrances,
dyes,
proteins,
cells)
focus
possible
strategies
incorporate
cargo
demonstrate
how
self-assembled
materials
several
Язык: Английский
L-Cysteine/Silver Nitrate/Iodate Anions System: Peculiarities of Supramolecular Gel Formation with and Without Visible-Light Exposure
Gels,
Год журнала:
2024,
Номер
10(12), С. 809 - 809
Опубликована: Дек. 9, 2024
In
this
study,
novel
anion
photo-responsive
supramolecular
hydrogels
based
on
cysteine-silver
sol
(CSS)
and
iodate
anions
(IO
Язык: Английский