
International Journal of Clinical and Health Psychology, Год журнала: 2024, Номер 24(4), С. 100526 - 100526
Опубликована: Окт. 1, 2024
Язык: Английский
International Journal of Clinical and Health Psychology, Год журнала: 2024, Номер 24(4), С. 100526 - 100526
Опубликована: Окт. 1, 2024
Язык: Английский
Journal of Affective Disorders, Год журнала: 2025, Номер 377, С. 235 - 244
Опубликована: Фев. 21, 2025
Язык: Английский
Процитировано
1BMC Public Health, Год журнала: 2025, Номер 25(1)
Опубликована: Фев. 5, 2025
Depression is a common mental health issue affecting volunteers, which directly impacts the quality of services they provide. This study investigates unique aspects volunteer depression and analyzes roles credits, stigmatization, personality traits, motivations in influencing levels. Data were collected from survey 822 volunteers Red Cross Hubei Province, China. The results indicate that higher credits significantly reduced scores, while increased stigmatization was associated with Personality traits such as agreeableness conscientiousness helped mitigate negative effects openness exacerbated its impact. Furthermore, driven by understanding value expression more susceptible to adverse stigmatization. findings highlight importance improving enhancing team trust reducing Although large sample size strengthens study, cross-sectional design limits causal inference. Overall, underscores developing effective support measures, thereby service community well-being.
Язык: Английский
Процитировано
0Frontiers in Pharmacology, Год журнала: 2025, Номер 16
Опубликована: Фев. 27, 2025
Anxiety disorders and depression often co-occur lack broadly available treatments. Gardenia extract significantly associated with treatment of anxiety-like depression. Based on the dose effect hypothesis previous studies, it is speculated that crocin I, main component gardenia, related to The present study aimed verify reversal I chronic corticosterone-induced depression, further explore its metabolic process in vivo. Ultimately, a new method for rapid sensitive detection trace substances was established. In this study, rat model induced by corticosterone. effects were explored combining behavioral, pathological sections ELASA data. It first time can reverse morphological changes hippocampus corticosterone rats. terms behavior, Ⅰ improve depressive behavior exhibited rats water maze sugar preference experiments. also repair neuronal cell damage Dentate gyrus, CA1, CA3 areas hippocampus. regulates expression levels monoamine neurotransmitters brain, thereby exerting an anti-anxiety-like effect. Pharmacokinetic analysis performed determine Further integrating Surface-Enhanced Raman Scattering (SERS) technology, highly had been discovered hippocampal morphology caused determined exert therapeutic regulating brain. vivo pharmacokinetic experiments revealed could not pass through intestinal barrier into blood, but metabolite crocetin blood. Finally, synthesizing silver nanoparticles, amounts blood samples established time.The calculated enhancement factor 4.49 × 1011. stable reproducible over week. This series studies great potential treating comorbid anxiety shortens distance from theoretical research clinical application.
Язык: Английский
Процитировано
0Journal of Psychiatric Research, Год журнала: 2024, Номер 181, С. 663 - 672
Опубликована: Дек. 22, 2024
Язык: Английский
Процитировано
1International Journal of Clinical and Health Psychology, Год журнала: 2024, Номер 24(4), С. 100526 - 100526
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
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