Abnormal presentation of pregnancy and postpartum initial-onset systemic lupus erythematosus combined with diffuse alveolar hemorrhage: A case report

Lupus, Год журнала: 2023, Номер 32(13), С. 1579 - 1582

Опубликована: Окт. 20, 2023

Systemic lupus erythematosus (SLE) is an autoimmune disease that most commonly occurs in women of childbearing age. However, cases SLE with abnormal pregnancy as the initial manifestation, involving development diffuse alveolar hemorrhage (DAH), have rarely been reported. Herein, we report case a young woman who underwent cesarean section for fetal distress and growth restriction at 35 + 1 weeks’ gestation. Following discharge, she experienced progressive worsening anemia chest tightness, which was later diagnosed complicated by DAH.

Язык: Английский

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Systemic Lupus Erythematosus in pregnancy – a multidisciplinary approach to family planning and adverse outcomes prevention

Quality in Sport, Год журнала: 2024, Номер 15, С. 52458 - 52458

Опубликована: Июль 8, 2024

Introduction and purpose Systemic Lupus Erythematosus is a chronic multisystemic autoimmune disease with periods of remissions flares [1,5,25]. Because its possible consequences unpredictability, it undoubtedly an issue for such patients to decide about pregnancy [3]. The main aim this review present the risks SLE in pregnancy, general management current recommendations regarding planning pre-/postnatal care. Review Methods For we conducted research scientific literature from PubMed books, applying keywords (below). Consequently, included our references above 20 selected articles published between 2017-2024 3 chapters different medical books. All these were analyzed terms their currency relevance. A brief description State Knowledge mostly affects women at reproductive age [2, 3,5]. It often requires long-term therapy that aims achieve maintain inactive stage by means numerous aggressive drugs. Its proper gestation even more challenging than usually, owing increased risk adverse outcomes (APO) higher maternal mortality [1,2,4,5,7]. Therefore, successful stratification, modification individually adjusted plan follow-up visits are most crucial conditions be met [1,6,7,13]. Summary Considering all potential complications may occur general, family should raised every female patient [5,6]. key best implementation strategies empowering active aware participant decision-making process [1,3,4,6,11].

Язык: Английский

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Construction and application of fetal loss risk model in systemic lupus erythematosus patients with mild disease severity

BMC Pregnancy and Childbirth, Год журнала: 2024, Номер 24(1)

Опубликована: Июль 23, 2024

Abstract Background This dynamic nomogram model was developed to predict the probability of fetal loss in pregnant patients with systemic lupus erythematosus (SLE) mild disease severity before conception. Methods An analysis conducted on 314 pregnancy records SLE who were hospitalized between January 2015 and 2022 at Shenzhen People's Hospital, Longhua Branch Hospital. Data from Hospital utilized as an independent external validation cohort. The nomogram, a widely used statistical visualization tool onset, progression, prognosis, survival, created after feature selection using multivariate logistic regression analysis. To evaluate prediction performance, we employed receiver operating characteristic curve, calibration decision curve Results Lupus nephritis, complement 3, immunoglobulin G, serum albumin, C-reactive protein, hydroxychloroquine all included model. demonstrated good discriminatory power, area under 0.867 (95% confidence interval: 0.787–0.947). According analysis, exhibited clinical importance when ranged 10 70%. predictive ability through validation. Conclusion approach may facilitate precise management

Язык: Английский

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Adverse Pregnancy Outcomes in Patients With Systemic Lupus Erythematosus: A Retrospective Cohort Study

ACTA MEDICA IRANICA, Год журнала: 2024, Номер unknown

Опубликована: Авг. 28, 2024

Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease that may result in adverse pregnancy outcomes, posing significant risk to both the mother and fetus. The major purpose of current study was investigate impact SLE on outcomes among women with SLE. This retrospective cohort study. Two groups pregnant women, one without SLE, were included at Gynecology Obstetrics Clinic Ayatollah Mousavi Hospital Zanjan, Iran, from 2019 2020. Participants cohorts completed checklist variables based their medical records. data analyzed using binary logistic regression, chi-square test, analysis variance, independent samples t-test SPSS software version 23. research involved 400 mean age non-SLE being 36.68±4.90 29.46±6.56 years, respectively. most prevalent outcome cesarean section (271 [67.8%]), significantly higher group (54.5% vs. 10.0%, P=0.0001). likelihood experiencing spontaneous abortion, preterm labor, section, LBW increased by more than 6.5 times (odds ratio, 6.54; 95% CI, 2.22-19.27; P=0.001), 3.6 3.67; 1.47-9.18; P=0.005), 18.9 18.94; 6.46-55.49; P=0.0001), 3 3.04; 1.09-8.46; P=0.030) individuals Women have an encountering delivering low-birth-weight infant.

Язык: Английский

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Lupus eritematoso sistémico: prevalencia, complicaciones y pruebas diagnósticas

Deleted Journal, Год журнала: 2024, Номер 4(4), С. 317 - 327

Опубликована: Авг. 30, 2024

El lupus eritematoso sistémico es una patología autoinmune de causa desconocida, caracterizada por alteración respuesta inmunológica y consecuente producción autoanticuerpos dirigidos a los antígenos celulares. Ministerio Salud Pública ecuatoriano indica que esta enfermedad prevalece más en mujeres relación 10:1 respecto hombres objetivo la investigación fue determinar prevalencia, complicaciones diagnóstico del sistémico. La metodología se llevó revisión bibliográfica, tipo descriptivo diseño documental, este utilizaron términos MeSH booleanos. En resultados destaca que, prevalencia media 55.80%. Las comunes son accidentes cerebrovasculares, preeclampsia, el embarazo pretérmino parto prematuro. Con las pruebas diagnósticas, realizan ELISA PCR. esto, concluye casos relativamente altos, especialmente mujeres, haciendo den durante embarazo.

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