Journal of Molecular Structure, Год журнала: 2024, Номер 1315, С. 138941 - 138941
Опубликована: Июнь 7, 2024
Язык: Английский
Journal of Molecular Structure, Год журнала: 2024, Номер 1315, С. 138941 - 138941
Опубликована: Июнь 7, 2024
Язык: Английский
Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2024, Номер 701, С. 134938 - 134938
Опубликована: Авг. 1, 2024
Язык: Английский
Процитировано
10Industrial Crops and Products, Год журнала: 2024, Номер 218, С. 118990 - 118990
Опубликована: Июнь 13, 2024
Язык: Английский
Процитировано
9Food Bioscience, Год журнала: 2025, Номер unknown, С. 106686 - 106686
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
1Journal of Nanobiotechnology, Год журнала: 2023, Номер 21(1)
Опубликована: Авг. 1, 2023
Abstract Type 2 diabetes mellitus (T2DM) predominantly considered a metabolic disease is now being an inflammatory as well due to the involvement of meta-inflammation. Obesity-induced adipose tissue inflammation (ATI) one earliest phenomena in case meta-inflammation, leading advent insulin resistance (IR) and T2DM. The key events ATI are orchestrated by macrophages, which aggravate state upon activation, ultimately systemic chronic low-grade Non-Alcoholic Steatohepatitis (NASH) through proinflammatory cytokines. CD44 receptor on macrophages overexpressed ATI, NASH, IR. Therefore, we developed targeted Hyaluronic Acid functionalized Graphene Oxide Quantum Dots (GOQD-HA) nanocomposite for tissue-specific delivery metformin. Metformin-loaded GOQD-HA (GOQD-HA-Met) successfully downregulated expression cytokines restored antioxidant status at lower doses than free metformin both palmitic acid-induced RAW264.7 cells diet induced obese mice. Our study revealed that nanocarrier enhanced efficacy Metformin primarily acting therapeutic agent apart from drug platform. properties stem HA GOQD having anti-inflammatory respectively. This unravels function option meta-inflammation where itself acts agent. Graphical
Язык: Английский
Процитировано
23Chemical Engineering Journal, Год журнала: 2023, Номер 480, С. 148205 - 148205
Опубликована: Дек. 19, 2023
Процитировано
23Advanced Materials, Год журнала: 2023, Номер 36(7)
Опубликована: Сен. 18, 2023
Microfluidics, with its remarkable capacity to manipulate fluids and droplets at the microscale, has emerged as a powerful platform in numerous fields. In contrast conventional closed microchannel microfluidic systems, free-boundary manufacturing (FBMM) processes continuous precursor into jets or relatively spacious environment. FBMM is highly regarded for superior flexibility, stability, economy, usability, versatility of advanced materials architectures. this review, comprehensive overview recent advancements provided, encompassing technical principles, material manufacturing, their applications. categorized based on foundational mechanisms, primarily comprising hydrodynamics, interface effects, acoustics, electrohydrodynamic. The mechanisms fluid manipulation are thoroughly discussed. Additionally, various dimensions ranging from zero-dimensional three-dimensional, well diverse applications science, biomedical engineering, engineering presented. Finally, current progress summarized future challenges prospected. Overall, review highlights significant potential tool wide-ranging
Язык: Английский
Процитировано
21Chemical Engineering Journal, Год журнала: 2023, Номер 476, С. 146907 - 146907
Опубликована: Окт. 24, 2023
Язык: Английский
Процитировано
20International Journal of Biological Macromolecules, Год журнала: 2024, Номер 263, С. 130283 - 130283
Опубликована: Фев. 18, 2024
Язык: Английский
Процитировано
8Journal of Energy Storage, Год журнала: 2024, Номер 90, С. 111933 - 111933
Опубликована: Май 10, 2024
Язык: Английский
Процитировано
7Composites Communications, Год журнала: 2024, Номер 49, С. 101977 - 101977
Опубликована: Июль 3, 2024
Язык: Английский
Процитировано
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