Time-Salt Type Superposition and Salt Processing of Poly(methacrylamide) Hydrogel based on Hofmeister Series

Macromolecules, Год журнала: 2024, Номер 57(6), С. 2746 - 2755

Опубликована: Фев. 22, 2024

Breakthrough to the extreme properties of polymer networks relies on new insights into their molecular dynamics. Time-salt concentration superposition has been discovered in polyelectrolyte coacervate systems, proving instrumental tuning mechanical performance hydrogels. However, time-salt type never mentioned existing literature. Herein, we reported that poly(methacrylamide) (PMAm) hydrogel can be systematically regulated a vast range by treating with different salts, for example, Young's modulus tuned from 10–2 103 MPa. The unusual behavior salt-stiffening arises salt-enhanced phase separation network and subsequent glassy transition polymer-rich phase. Rheological results demonstrate dynamic hydrogels superposed onto "time-salt type" master curves salt types aligning along Hofmeister series. shift factor exhibits correlation mobility water molecules as revealed low-field nuclear magnetic resonance spectroscopy. A polymer–water–salt ternary interaction mechanism was proposed elucidate equivalent behavior. Guided principle, processing strategy brought up expand property limits PMAm hydrogel. With simply switching employed, could either stiff wear-resistant material akin plastics or soft flowable gel utilizable recycling.

Язык: Английский

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Ionic organohydrogel with long-term environmental stability and multifunctionality based on PAM and sodium alginate

Chemical Engineering Journal, Год журнала: 2024, Номер 485, С. 149810 - 149810

Опубликована: Фев. 17, 2024

Язык: Английский

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GelMA hydrogel: A game-changer in 3D tumor modeling

Materials Today Chemistry, Год журнала: 2024, Номер 38, С. 102111 - 102111

Опубликована: Май 16, 2024

Currently, researchers have increasingly focused on 3D in vitro tumor models as they possess the capacity to replicate tissue-like characteristics and cell-cell interactions within microenvironment. Hydrogel, a hydrophilic polymer network that crosslinks structure, has emerged prominent cynosure due its ability absorb water, swell, provide attachment sites for cells. By mimicking extracellular matrix, hydrogel facilitates investigation of cell growth interaction. The gelatin methacrylate (GelMA) garnered significant interest scientific community be mechanically adjusted exceptional biocompatibility. This review primarily focuses recent advancements construction methodology utilizing GelMA hydrogel, including preparation procedures, attributes, performance enhancements. Furthermore, we offer insights into prospective directions advancement hydrogels. It is anticipated hydrogels will find extensive application near future precise fabrication with diverse geometries. These are poised become preferred option investigating microenvironment, tumorigenesis, metastasis, related mechanisms.

Язык: Английский

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Living organisms growth and release immobilized in an assembled dipeptide hydrogel

Journal of Colloid and Interface Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Importance of nanocomposites in 3D bioprinting: An overview

Bioprinting, Год журнала: 2023, Номер 32, С. e00280 - e00280

Опубликована: Май 18, 2023

Язык: Английский

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Bioprinting: Mechanical Stabilization and Reinforcement Strategies in Regenerative Medicine

Tissue Engineering Part A, Год журнала: 2024, Номер 30(13-14), С. 387 - 408

Опубликована: Янв. 11, 2024

Bioprinting describes the printing of biomaterials and cell-laden or cell-free hydrogels with various combinations embedded bioactive molecules. It encompasses precise patterning cells to create scaffolds for different biomedical needs. There are many requirements that bioprinting face, it is ultimately interplay between scaffold's structure, properties, processing, performance will lead its successful translation. Among essential properties must possess—adequate appropriate application-specific chemical, mechanical, biological performance—the mechanical behavior hydrogel-based bioprinted key their stable in vivo at site implantation. Hydrogels typically constitute main scaffold material medium biomolecules very soft, often lack sufficient stability, which reduces printability and, therefore, potential. The aim this review article highlight reinforcement strategies used approaches achieve enhanced stability bioinks printed scaffolds. Enabling robust materials processes creation truly complex remarkable structures could accelerate application smart, functional settings. a powerful tool fabrication 3D applications. has gained tremendous attention recent years, bioink library expanding include more combinations. From practical perspective, need be considered, such as structure's performances. these, constructs critical translation into clinic. explore stabilization structures.

Язык: Английский

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The cutting‐edge progress in bioprinting for biomedicine: principles, applications, and future perspectives

MedComm, Год журнала: 2024, Номер 5(10)

Опубликована: Сен. 23, 2024

Bioprinting is a highly promising application area of additive manufacturing technology that has been widely used in various fields, including tissue engineering, drug screening, organ regeneration, and biosensing. Its primary goal to produce biomedical products such as artificial implant scaffolds, tissues organs, medical assistive devices through software-layered discrete numerical control molding. Despite its immense potential, bioprinting still faces several challenges. It requires concerted efforts from researchers, engineers, regulatory bodies, industry stakeholders are principal overcome these challenges unlock the full potential bioprinting. This review systematically discusses principles, applications, future perspectives while also providing topical overview research progress over past two decades. The most recent advancements comprehensively reviewed here. First, printing techniques methods summarized along with related bioinks supporting structures. Second, interesting representative cases regarding applications biosensing introduced detail. Finally, remaining suggestions for directions proposed discussed. one areas fields. aims devices. perspectives, which provides description

Язык: Английский

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Peptide‐Based Optical/Electronic Materials: Assembly and Recent Applications in Biomedicine, Sensing, and Energy Storage

Macromolecular Bioscience, Год журнала: 2023, Номер 23(12)

Опубликована: Июль 19, 2023

The unique optical and electronic properties of living systems are impressive. Peptide-based supramolecular self-assembly attempt to mimic these by preparation optical/electronic function materials with specific structure through simple building blocks, rational molecular design, kinetic stimulation. From the perspective blocks assembly strategies, peptide-based nanostructures, including peptides regulate external subunits, systematically reviewed. Additionally, their applications in biomedicine, sensing, energy storage also highlighted. This bioinspired material is one hot candidates for new generation green intellect materials, many advantages such as biocompatibility, environmental friendliness, adjustable morphology.

Язык: Английский

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Application of smart-responsive hydrogels in nucleic acid and nucleic acid-based target sensing: A review

Biosensors and Bioelectronics, Год журнала: 2024, Номер 267, С. 116803 - 116803

Опубликована: Сен. 19, 2024

Язык: Английский

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NIR light-triggered mechanically mutable mussel-inspired hydrogels for developing smart wearable sensing

Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 158603 - 158603

Опубликована: Дек. 1, 2024

Язык: Английский

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