Analytical Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 15, 2025
Arginine
(Arg)
is
involved
in
tissue
metabolism
and
regulates
the
immune
function;
thereby,
achieving
detection
of
Arg
crucial
for
early
diagnosis
treatment
diseases.
Herein,
dual
ratiometric
fluorescence
sensors
were
prepared
with
blue
emission
levorotatory/dextrorotatory
carbon
dots
(CDs)
red
porphyrin
(L/D-CDs-PP)
sensitive
portable
Arg.
Interestingly,
L-CDs-PP
D-CDs-PP
displayed
not
only
peaks
at
493
650
nm
but
also
different
response
modes
to
Arg;
thus,
they
could
serve
as
achieve
accurate
reliable
Arg,
limit
23.87
μM
2.39
D-CDs-PP.
Importantly,
solid-state
successfully
achieved
dual-mode
visual
support
a
smartphone
platform.
In
addition,
exhibited
excellent
biocompatibility
cell
imaging
capabilities,
cells
biological
samples
urine
rat
plasma.
Therefore,
broad
application
prospects
fields
analytical
sensing,
imaging,
medical
diagnosis.
Nature Communications,
Год журнала:
2025,
Номер
16(1)
Опубликована: Фев. 25, 2025
Cryptochiral
compounds
are
indispensable
in
biology
systems
and
medical
applications,
yet
the
development
of
high-performance
detection
method
remains
challenging.
Here,
we
report
a
hinge-like
dinuclear
Pt(II)
complex
as
stereodynamic
probe
for
cryptochirality
sensing.
This
features
constrained,
closed
conformation
achieved
through
synergistic
intramolecular
π
−
stacking
metal-metal
interactions
between
cyclometalated
wings.
The
shows
robust
chiroptical
response
to
center-to-axial
chiral
induction
during
rapid
condensation
with
cryptochiral
that
adopts
more
energetically
favorable
conformation.
resulting
intense
Cotton
effects
at
long
wavelengths
enable
in-situ
circular
dichroism
analysis
determinate
absolute
configuration
enantiometric
composition
molecules.
Furthermore,
near-infrared
phosphorescence
characteristics
hinge
have
been
explored
develop
it
an
optical
sensor
accurate
quantification
With
its
dual
CD
capabilities,
this
great
potential
high-throughput
screening
analysis.
authors
complexes
probes