Ternary Schottky Junction for Sonocatalytic Water Splitting in Gas‐Immunotherapy‐Mediated Cancer Treatment

Advanced Science, Год журнала: 2025, Номер unknown

Опубликована: Фев. 8, 2025

Hydrogen therapy has shown new potential in cancer treatment, particularly high-pressure and hypoxic areas, where it demonstrates the ability to alter tumor microenvironment regulate metabolism. disrupts mitochondrial function of cells, interferes with their energy metabolism, ultimately leads depletion apoptosis. In this study, a sonocatalyst (BPM), is designed generate hydrogen oxygen situ within tumors, further enhancing therapeutic efficacy. The mesocrystalline structure BPM, composed bismuth fluoride, polyoxometalates, molybdenum carbide, significantly improves charge separation electron transfer efficiency under ultrasound irradiation, resulting an efficient water-splitting reaction. By simultaneously generating depleting glutathione, BPM effectively triggers oxidative stress alleviates hypoxia, thereby disrupting inhibiting metabolism cells. Additionally, enhances antitumor immune responses by promoting dendritic cell maturation, activating T lymphocytes, polarizing macrophages toward M1 phenotype, reversing immunosuppressive state microenvironment. results indicate that holds for gas-immunotherapy combination treatments, offering multifunctional strategy improve outcomes.

Язык: Английский

---

Anion exchange regulated charge separation engineering in bismuth nanoflowers for sonocatalytic radio-immunotherapy

Journal of Colloid and Interface Science, Год журнала: 2025, Номер 687, С. 801 - 816

Опубликована: Фев. 17, 2025

Язык: Английский

---

Recent advances of piezoelectric materials used in sonodynamic therapy of tumor

Coordination Chemistry Reviews, Год журнала: 2024, Номер 523, С. 216282 - 216282

Опубликована: Окт. 22, 2024

Язык: Английский

---

Construction of Bi/Bi2O3 particles embedded in carbon sheets for boosting the storage capacity of potassium-ion batteries

Journal of Colloid and Interface Science, Год журнала: 2024, Номер 674, С. 634 - 642

Опубликована: Июнь 27, 2024

Язык: Английский

---

Ultrasound-enhanced dual-responsive bismuth nanocatalysts for alleviating tumor hypoxia and promoting breast cancer sonodynamic-immunotherapy

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 160292 - 160292

Опубликована: Фев. 1, 2025

Язык: Английский

---

Nanozyme as tumor energy homeostasis disruptor mediated ferroptosis for high-efficiency radiotherapy

Journal of Colloid and Interface Science, Год журнала: 2025, Номер 688, С. 44 - 58

Опубликована: Фев. 19, 2025

Язык: Английский

---

Exploration of bismuth-based nanomaterials: From fundamental concepts to innovative synthesis techniques and emerging applications

Coordination Chemistry Reviews, Год журнала: 2025, Номер 538, С. 216687 - 216687

Опубликована: Апрель 22, 2025

Язык: Английский

---

Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

BMEMat, Год журнала: 2024, Номер unknown

Опубликована: Окт. 25, 2024

Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical tumor treatment through radiotherapy. Despite their widespread use, optimizing X‐ray efficacy remains critical challenge due to issues such as resistance damage surrounding health tissues. Recent advancements nanotechnology have introduced new opportunities challenges cancer diagnosis treatment. This review summarizes the latest progress nanomaterials for X‐ray‐triggered therapy, highlighting various advantages targeted delivery, reduced side effects, enhanced therapeutic efficacy. We examine how nanomaterials, including metals, metal oxides, sulfides, fluorides, rare earth cluster compounds, metal‐organic frameworks, nanohybrids, enhance effectiveness treatments. Furthermore, we address current future prospects efficient aiming provide comprehensive overview researchers clinicians field.

Язык: Английский

---

Smart bismuth-based platform: A focus on radiotherapy and multimodal systems

Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 101, С. 106136 - 106136

Опубликована: Авг. 30, 2024

Язык: Английский

---

Bismuth-Based Mesoporous Nanoball Carrying Sorafenib for Synergistic Photothermal and Molecularly-Targeted Therapy in an Orthotopic Hepatocellular Carcinoma Xenograft Mouse Model

Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 245, С. 114279 - 114279

Опубликована: Окт. 1, 2024

Язык: Английский

---