Electrochemical Biosensor Based on Dual-Ligand Functionalized Lanthanide-Encapsulated Polyoxometalate Conductive Polymer Film for Detecting Broad-Spectrum Tumor Marker MicroRNA-155 DOI

Lina Meng,

Xiaodan Jia,

Zhigang Tang

и другие.

Inorganic Chemistry, Год журнала: 2024, Номер 63(46), С. 22149 - 22161

Опубликована: Ноя. 1, 2024

In this work, a dual-ligand functionalized lanthanide-encapsulated selenotungstate [H2N(CH3)2]16Na2H10[Ho6(H2O)10(HPACA)4W10O28(Ac)2][SeW9O33]6 · 60H2O (1, HPACA = 2-pyrazinecarboxylic acid, HAc acetic acid) was successfully acquired by simultaneously incorporating rigid and flexible Ac– ligands to one reaction system. Interestingly, the polyanion [Ho6(H2O)10(HPACA)4W10O28(Ac)2][SeW9O33]628– of 1 is composed six trivacant Keggin-type [B-α-SeW9O33]8– units interconnected through an organic–inorganic hybrid bimetallic [Ho6(H2O)10(HPACA)4W10O28(Ac)2]20+ cluster. Moreover, 1@PNMPy film (PNMPy poly(N-methylpyrrole)) prepared electrochemical polymerization strategy. The doping significantly narrows bandgap in film, which enables exhibit remarkable conductivity rapid electron transfer capability. Then, film-modified glassy carbon electrode used construct 1@PNMPy-based biosensor (ECBS), achieves sensitive detection (a low limit 0.108 fM wide concentration range 10–8–10–15 M) for broad-spectrum tumor marker microRNA-155. Also, ECBS has good specific recognition performance microRNA-155 variety interfering media. research not only contributes deeper understanding synthetic chemistry multicomponent polyoxometalate (POM)-based materials but also can further expand innovative applications POM-based devices.

Язык: Английский

Engineered Conductive Metal–organic Frameworks for Electrochemical Detection of Urinary Biomarkers DOI
Brij Mohan, Muhammad Bilal Asif, Armando J. L. Pombeiro

и другие.

Small, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 22, 2024

Abstract The increasing prevalence of health concerns has sparked a demand for advanced monitoring tools, which is significant challenge researchers. Analysis biofluid samples and biomarker vital comprehensive assessment. In this context, metal–organic frameworks (MOFs) have emerged as one the leading materials developing cutting‐edge artificial sensors. These unique MOFs been developed from metallic organic linkers consist tunable pores dynamic surface areas, attracting various guest molecules to participate in electrochemical devices. This study gateway world where MOF designs transcend mere inventions, morphing into electric marvels that revolutionize urine sample monitoring. From inception design fabrication sensors tailored applications, prides itself on elucidating factors affecting MOF‐based electrical devices Moreover, focus placed conductivity, electrode properties, recent state‐of‐the‐art analysis, highlighting pivotal role biomarkers play honing resilience performance Finally, specific used analysis. It will attract researchers develop new portable tools by analyzing samples.

Язык: Английский

Процитировано

7

Highly conductive and stable double network carrageenan organohydrogels for advanced strain sensing and signal recognition arrays DOI
Xinlong Liu,

Longmeng Du,

Yong Ma

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 279, С. 135029 - 135029

Опубликована: Авг. 27, 2024

Язык: Английский

Процитировано

3

Characterization of Chiral Thiophene Multilayer 3D Polymers with AIE Properties for Environmental Monitoring of Chromium Ions DOI
Sai Zhang, Qingzheng Xu,

Qingkai Yuan

и другие.

Macromolecular Rapid Communications, Год журнала: 2025, Номер unknown

Опубликована: Апрель 14, 2025

Abstract This study reports the synthesis and characterization of novel thiophene‐based multilayer 3D chiral polymers incorporating methoxy octyloxy functional groups. These exhibit unique fluorescence properties, including a pronounced aggregation‐induced emission (AIE) phenomenon at lower excitation wavelength than previously reported thiophene systems. Additionally, demonstrate remarkable sensitivity in detecting hexavalent chromium ions (Cr 6+ ), significant environmental pollutant. The interaction between Cr leads to measurable changes fluorescence, highlighting their potential for applications monitoring biosensing. Importantly, these are effective actual water, where they maintain selectivity despite presence competing metal ions. enhanced further underscores suitability real‐world applications. work contributes field emphasizes versatility advanced sensing

Язык: Английский

Процитировано

0

Electrochemical Biosensor Based on Dual-Ligand Functionalized Lanthanide-Encapsulated Polyoxometalate Conductive Polymer Film for Detecting Broad-Spectrum Tumor Marker MicroRNA-155 DOI

Lina Meng,

Xiaodan Jia,

Zhigang Tang

и другие.

Inorganic Chemistry, Год журнала: 2024, Номер 63(46), С. 22149 - 22161

Опубликована: Ноя. 1, 2024

In this work, a dual-ligand functionalized lanthanide-encapsulated selenotungstate [H2N(CH3)2]16Na2H10[Ho6(H2O)10(HPACA)4W10O28(Ac)2][SeW9O33]6 · 60H2O (1, HPACA = 2-pyrazinecarboxylic acid, HAc acetic acid) was successfully acquired by simultaneously incorporating rigid and flexible Ac– ligands to one reaction system. Interestingly, the polyanion [Ho6(H2O)10(HPACA)4W10O28(Ac)2][SeW9O33]628– of 1 is composed six trivacant Keggin-type [B-α-SeW9O33]8– units interconnected through an organic–inorganic hybrid bimetallic [Ho6(H2O)10(HPACA)4W10O28(Ac)2]20+ cluster. Moreover, 1@PNMPy film (PNMPy poly(N-methylpyrrole)) prepared electrochemical polymerization strategy. The doping significantly narrows bandgap in film, which enables exhibit remarkable conductivity rapid electron transfer capability. Then, film-modified glassy carbon electrode used construct 1@PNMPy-based biosensor (ECBS), achieves sensitive detection (a low limit 0.108 fM wide concentration range 10–8–10–15 M) for broad-spectrum tumor marker microRNA-155. Also, ECBS has good specific recognition performance microRNA-155 variety interfering media. research not only contributes deeper understanding synthetic chemistry multicomponent polyoxometalate (POM)-based materials but also can further expand innovative applications POM-based devices.

Язык: Английский

Процитировано

2