Covalent organic frameworks: Advancing antimicrobial photodynamic therapy for next-generation treatments

Coordination Chemistry Reviews, Год журнала: 2025, Номер 528, С. 216424 - 216424

Опубликована: Янв. 11, 2025

Язык: Английский

---

Molecular Strategies for Constructing Epoxy‐Type Afterglow Probes in Disease Diagnosis and Treatment

Advanced Functional Materials, Год журнала: 2025, Номер unknown

Опубликована: Апрель 18, 2025

Abstract Epoxy‐type afterglow luminescence is a cascade reaction of photochemical defects caused as result the formation and release epoxy intermediates, exhibiting continuous phenomenon that remains intrinsic after excitation, with extremely impressive signal‐to‐background ratio (SBR) level in vivo. Afterglow based on this epoxy‐type mechanism ideally suited for applications developments diagnosis treatment biological diseases. In tutorial review, work aims to deeply elaborate mechanisms materials present application imaging Lastly, future perspectives potential challenges technology preclinical diagnostic, therapeutic, predictive analyses, well clinical translations are discussed.

Язык: Английский

---

Anthracene‐Based Endoperoxides as Self‐Sensitized Singlet Oxygen Carriers for Hypoxic‐Tumor Photodynamic Therapy

Advanced Healthcare Materials, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 6, 2024

Abstract Singlet oxygen is a crucial reactive species (ROS) in photodynamic therapy (PDT). However, the hypoxic tumor microenvironment limits production of cytotoxic singlet through light irradiation PDT photosensitizers (PSs). This restriction poses major challenge improving effectiveness PDT. To overcome this challenge, researchers have explored development carriers that can capture and release physiological conditions. Among these developments, anthracene‐based endoperoxides, initially discovered almost 100 years ago, shown ability to generate controllably under thermal or photo stimuli. Recent advancements led new class self‐sensitized anthracene‐endoperoxides, with potential applications enhancing effects for tumors. review discusses current research progress utilizing anthracene‐endoperoxides as improved It covers anthracene‐conjugated small organic molecules, metal–organic complexes, polymeric structures, other nano‐structures. The molecular structural designs, mechanisms, characteristics systems will be discussed. aims provide valuable insights developing high‐performance hypoxic‐tumor

Язык: Английский

---

NIR-activated multifunctional agents for the combined application in cancer imaging and therapy

Advances in Colloid and Interface Science, Год журнала: 2024, Номер 336, С. 103356 - 103356

Опубликована: Ноя. 22, 2024

Язык: Английский

---