Association of postoperative delirium with hypotension in critically ill patients after cardiac surgery: a prospective observational study DOI Creative Commons

Saleh Mohammed Alhaj Othman,

Mohammed Ali Ali Aziz,

Gaber Musaed Ali Al-Mushiki

и другие.

Journal of Cardiothoracic Surgery, Год журнала: 2024, Номер 19(1)

Опубликована: Авг. 1, 2024

Abstract Background Postoperative delirium (POD), an acute and variable disturbance in cognitive function, is intricate elusive phenomenon that occurs after cardiac surgery. Despite progress surgical techniques perioperative management, POD remains a formidable challenge, imposing significant burden on patients, caregivers, healthcare systems. Methods This prospective observational study involved 307 patients who underwent Data the occurrence of delirium, clinical parameters, postoperative characteristics were collected. A multivariate analysis was performed to assess relationship between POH POD. Results Sixty-one (21%) developed with average onset approximately 5 days postoperatively duration 6 days. On analysis, significantly associated POD, adjusted odds ratios indicated more likely develop (OR, 5.61; p = 0.006). Advanced age 1.11; 0.002), emergency surgery 8.31; 0.001), on-pump coronary artery bypass grafting identified as risk factors Patients typically older, be male, had higher morbidity rates than those did not. Conclusion critically ill Surgical complexity advanced contribute developing poor outcomes.

Язык: Английский

Intraoperative hypotension and postoperative delirium in elderly male patients undergoing laryngectomy: a single-center retrospective cohort study DOI Creative Commons
Yiru Wang, Kaizheng Chen, Min Ye

и другие.

Brazilian Journal of Anesthesiology (English Edition), Год журнала: 2024, Номер unknown, С. 844560 - 844560

Опубликована: Сен. 1, 2024

Postoperative Delirium (POD) is a common, transient postoperative cognitive dysfunction in elderly patients. The relationship between POD and intraoperative hypotension remains unclear. This study aims to determine if predicts male patients undergoing laryngectomy.

Язык: Английский

Процитировано

2
Diagnostic Efficacy of Carotid Ultrasound for Predicting the Risk of Perioperative Hypotension or Fluid Responsiveness: A Meta-Analysis DOI Creative Commons
Kuo‐Chuan Hung, Yen‐Ta Huang,

Wen-Wen Tsai

и другие.

Diagnostics, Год журнала: 2023, Номер 13(13), С. 2290 - 2290

Опубликована: Июль 6, 2023

Despite the acceptance of carotid ultrasound for predicting patients’ fluid responsiveness in critical care and anesthesia, its efficacy hypotension remains unclear perioperative setting. Electronic databases were searched from inception to May 2023 identify observational studies focusing on use corrected blood flow time (FTc) respirophasic variation artery peak velocity (ΔVpeak) assessing risks responsiveness. Using FTc as a predictive tool (four studies), analysis yielded pooled sensitivity 0.82 (95% confidence interval (CI): 0.72 0.89) specificity 0.94 CI: 0.88 0.97) risk (area under curve (AUC): 0.95). For responsiveness, 0.79 0.84) 0.81 0.75 0.86), respectively (AUC: 0.87). In contrast, ΔVpeak predict showed 0.76 0.63 0.85) 0.74 0.66 0.8) 0.79). The current meta-analysis provides robust evidence supporting high diagnostic accuracy which requires further verification.

Язык: Английский

Процитировано

4
Lower alpha frequency of intraoperative frontal EEG is associated with postoperative delirium: A secondary propensity-matched analysis DOI Creative Commons
Darren Hight,

Alexander Ehrhardt,

Friedrich Lersch

и другие.

Journal of Clinical Anesthesia, Год журнала: 2023, Номер 93, С. 111343 - 111343

Опубликована: Ноя. 22, 2023

Postoperative delirium (POD) is a serious complication of surgery, especially in the elderly patient population. It has been proposed that decreasing amount anesthetics by titrating to an EEG index will lower POD rate, but clear evidence missing. A strong age-dependent negative correlation reported between peak oscillatory frequency alpha waves and end-tidal anesthetic concentration, with older patients generating slower frequencies. We hypothesized, oscillations are associated higher rate POD.

Язык: Английский

Процитировано

4
Postoperative delirium in geriatric patients with thoracic and orthopedic surgery DOI

Zhongpeng Sun

Journal of Clinical Anesthesia, Год журнала: 2024, Номер 94, С. 111399 - 111399

Опубликована: Янв. 20, 2024

Язык: Английский

Процитировано

1
The use of drugs to prevent postoperative delirium in elderly patients with radical esophagectomy DOI

Xin‐Tao Li,

Fu‐Shan Xue, Xinyue Li

и другие.

Esophagus, Год журнала: 2024, Номер 21(2), С. 176 - 177

Опубликована: Янв. 24, 2024

Язык: Английский

Процитировано

1
Machine Learning-Based Prediction of Post-Induction Hypotension: Identifying Risk Factors and Enhancing Anesthesia Management DOI Creative Commons
Ming Chen, Dingyu Zhang

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Фев. 2, 2024

Abstract Background: Post-induction hypotension (PIH) increases surgical complications including myocardial injury, acute kidney delirium, stroke, prolonged hospitalization, and endangerment of the patient's life. Machine learning is an effective tool to analyze large amounts data identify perioperative complication factors. This study aims risk factors for PIH develop predictive models support anesthesia management. Methods: A dataset 5406 patients was analyzed using machine methods. Logistic regression, random forest, XGBoost, neural network were compared. Model performance evaluated area under receiver operating characteristic curve (AUROC), calibration curves, decision analysis (DCA). Results: The logistic regression model achieved highest AUROC 0.74 (95% CI, 0.71 - 0.77), indicating good discrimination. Calibration curves demonstrated satisfactory forest models. DCA revealed that had clinical benefit. showed best in predicting selected as final model. Baseline blood pressure, age, sex, type surgery, platelet count, certain anesthesia-inducing drugs identified important features. Conclusions: provides a valuable personalized preoperative assessment customized management, allowing early intervention improved patient outcomes. Integration into electronic medical record systems can facilitate real-time prediction.

Язык: Английский

Процитировано

1
The genetic relationship between hypotension and delirium: a Mendelian randomization study DOI Creative Commons
Chengli Wang,

Jiayao Wu,

Yiqing Lin

и другие.

Frontiers in Neurology, Год журнала: 2024, Номер 15

Опубликована: Июль 17, 2024

Observational research suggests that hypotension is a potential hazard factor of delirium. Nevertheless, previous observational articles are limited in their ability to establish causality between and The present study was sought explore the genetic causal relationship these two conditions using two-sample Mendelian randomization (MR).

Язык: Английский

Процитировано

1
Definition of clinically relevant intraoperative hypotension: A data-driven approach DOI Creative Commons
Mathias Maleczek, Daniel Laxar, Angelika Geroldinger

и другие.

PLoS ONE, Год журнала: 2024, Номер 19(11), С. e0312966 - e0312966

Опубликована: Ноя. 1, 2024

Associations between intraoperative hypotension (IOH) and various postoperative outcomes were shown in retrospective trials using a variety of different definitions IOH. This complicates the comparability these makes clinical application difficult. Information about best performing IOH regarding 30-day mortality, hospital length stay (hLOS), postanesthesia care unit (PACU-LOS) is missing.

Язык: Английский

Процитировано

1
Assessing the Efficacy of Inferior Vena Cava Collapsibility Index for Predicting Hypotension after Central Neuraxial Block: A Systematic Review and Meta-Analysis DOI Creative Commons
Ying-Jen Chang, Chien‐Cheng Liu, Yen‐Ta Huang

и другие.

Diagnostics, Год журнала: 2023, Номер 13(17), С. 2819 - 2819

Опубликована: Авг. 31, 2023

The use of ultrasonography to predict spinal-induced hypotension (SIH) has gained significant attention. This diagnostic meta-analysis aimed investigate the reliability inferior vena cava collapsibility index (IVCCI) in predicting SIH patients undergoing various surgeries. Databases, including Embase, Cochrane Library, Medline, and Google Scholar, were screened until 28 July 2023, yielding 12 studies with 1076 (age range: 25.6–79 years) cesarean section (CS) (n = 4) or non-CS surgeries 8). Patients had a significantly higher IVCCI than those without (mean difference: 11.12%, 95% confidence interval (CI): 7.83–14.41). pooled incidence rate was 40.5%. demonstrated satisfactory overall (sensitivity, 77%; specificity, 82%). area under curve (AUC) 0.85, indicating its high capability differentiate at risk PSH. Fagan nomogram plot positive likelihood ratio (PLR) 4 negative (NLR) 0.28. results underscore robustness discriminative ability as predictive tool for SIH. Nevertheless, future investigations should focus on assessing applicability high-risk exploring potential enhancement patient safety through incorporation into clinical practice.

Язык: Английский

Процитировано

3
Clinical investigation into risk factors for delirium post-cardiac surgery and its implications for nursing intervention guided by behavior change theory DOI Creative Commons
Youwei Zhao,

Shichao Guo,

Zhiyuan Wang

и другие.

Journal of Cardiothoracic Surgery, Год журнала: 2024, Номер 19(1)

Опубликована: Окт. 17, 2024

This study explores the factors contributing to occurrence of delirium following cardiac surgery and devises nursing strategies rooted in behavior change theory.

Язык: Английский

Процитировано

0