ACS Applied Bio Materials, Год журнала: 2024, Номер 7(5), С. 2637 - 2659

Опубликована: Апрель 30, 2024

Extensive research has been conducted on the application of nanoparticles in treatment cancer and infectious diseases. Due to their exceptional characteristics flexible structure, they are classified as highly efficient drug delivery systems, ensuring both safety targeted delivery. Nevertheless, still encounter obstacles, such biological instability, absence selectivity, recognition unfamiliar elements, quick elimination, which restrict remedial capacity. To surmount these drawbacks, biomimetic nanotechnology developed that utilizes T cell natural killer (NK) membrane-encased sophisticated methods administering drugs. These can extend duration circulation avoid immune system clearance. During membrane extraction coating procedure, surface proteins immunological cells transferred nanoparticles. Such present confer several benefits nanoparticles, including prolonged circulation, enhanced targeting, controlled release, specific cellular contact, reduced vivo toxicity. This review focuses nanosystems derived from membranes NK comprehensive manufacture, applications viral infections. Furthermore, potential applications, prospects, existing challenges medical implementation highlighted.

Язык: Английский