Transferosome-Enhanced Transdermal Therapy: A Novel Approach for Duloxetine Delivery for Management of Neuropathic Pain DOI
Pramod S. Salve,

Mohammad Qutub,

Ujban Hussain

и другие.

BioNanoScience, Год журнала: 2025, Номер 15(2)

Опубликована: Март 17, 2025

Язык: Английский

Development of curcumin-loaded ultra deformable lipid vesicles for enhanced anti-melanoma activity: in vitro, ex-vivo, and cell line studies DOI
Malleswara Rao Peram, S. Vidyadhara, S. R. Patil

и другие.

Journal of Dispersion Science and Technology, Год журнала: 2025, Номер unknown, С. 1 - 18

Опубликована: Фев. 4, 2025

Язык: Английский

Процитировано

0
Folic acid grafted Tofacitinib loaded targeted Transfersomes for Transdermal delivery against Breast cancer. DOI
Iqra Afzal,

Ahmed Zeb,

Danish Mazhar

и другие.

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 106711 - 106711

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Assessment of therapeutic effectiveness of developed colchicine transnovasomes in treatment of Recurrent Aphthous Ulcer as monotherapy and combination therapy with platelet-rich plasma DOI

Soha M. Kandil,

Iman I. Soliman,

M. Hosni

и другие.

Pharmaceutical Development and Technology, Год журнала: 2025, Номер unknown, С. 1 - 26

Опубликована: Март 7, 2025

Transnovasomes is a new and exciting class of lipid-based nanovesicles. Colchicine (COL) hydrophilic natural alkaloid with anti-inflammatory anti-mitotic features having oral administration permeation defects. Recurrent Aphthous Ulcer (RAU) the most prevalent disease mucosa suffering from lack particular final preventative therapy. So, designing prolonged effective specialized delivery system for ulcer treatment important. transnovasomes (COL-TNs) were prepared using surfactants (Span 60 & Span 80), free fatty acids (Oleic acid Stearic acid), Cholesterol Brij 58. The COL-TNs evaluated their vesicle size (VS), polydispersity index (PDI), zeta potential (ZP), entrapment efficiency (EE%), ex-vivo after 12 hours (Q12h). Values VS, PDI, ZP, EE% Q12h optimized formulation 256.74 ± 11.2 nm, 0.322 0.08, -43.3 0.62, 85.35 3.7% 72.69 5.84% respectively. Drug accumulation was ninefold greater than drug solution 8 hours. In-vivo, formulation, alone or in combination platelet-rich plasma (PRP), achieved complete healing acetic-acid induced RAU restoring normal levels assayed biomarkers (TNF- α, NF-κβ, IL-6, MMP9, VEGF) histological mucosa. In conclusion, can be used as promising, safe, efficient RAU, monotherapy therapy PRP.

Язык: Английский

Процитировано

0
Enhancing Cutaneous Efficacy of Ketoprofen through Nanocarrier-based Formulations: A Scoping Review DOI
Marcel Henrique Marcondes Sari,

Nathalia Marçallo Peixoto Souza,

P. Silva

и другие.

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер 107, С. 106788 - 106788

Опубликована: Март 5, 2025

Язык: Английский

Процитировано

0
Transferosome-Enhanced Transdermal Therapy: A Novel Approach for Duloxetine Delivery for Management of Neuropathic Pain DOI
Pramod S. Salve,

Mohammad Qutub,

Ujban Hussain

и другие.

BioNanoScience, Год журнала: 2025, Номер 15(2)

Опубликована: Март 17, 2025

Язык: Английский

Процитировано

0