eXPRESS Polymer Letters,
Год журнала:
2023,
Номер
18(2), С. 160 - 192
Опубликована: Дек. 6, 2023
Polymer-based
hydrogels
are
hydrophilic
polymer
networks
with
a
remarkable
capacity
to
absorb
substantial
amounts
of
water
and
biological
fluids,
rendering
them
highly
attractive
for
drug
delivery
applications.The
COVID-19
pandemic
has
acted
as
catalyst
research
innovation
in
the
realm
polymer-based
delivery,
particular
emphasis
on
antiviral
therapeutics,
vaccines,
diagnostics,
precision
respiratory
system.The
distinctive
attributes
hydrogels,
such
their
biocompatibility,
customizable
release
profiles,
ease
functionalization,
establish
versatile
platforms
development
advanced
systems
combat
not
only
but
also
spectrum
other
infectious
diseases.This
study
is
dedicated
scruti-nizing
evaluating
characteristics
employed
treatment
diseases
associated
SARS-CoV-2
virus.Furthermore,
investigation
introduces
novel
classification
system
deployed
SARS-CoV-2-related
diseases.Additionally,
paper
provides
an
up-to-date
evaluation
latest
developed
utilized
dis-eases
linked
virus,
based
conducted
through
recent
months
2023.
Abstract
Polysaccharides,
also
known
as
glycans,
are
biological
macromolecules
consisting
of
many
monosaccharide
units.
Alongside
proteins,
nucleic
acids,
and
lipids,
they
constitute
the
four
fundamental
substances
crucial
for
life
activities
essential
growth
development
living
organisms.
As
natural
products
with
inherent
activity,
polysaccharides
widely
available,
nontoxic,
possess
numerous
functional
properties,
holding
immense
potential
advancement
in
food,
medicine,
cosmetics.
Furthermore,
exploration
polysaccharide‐based
drugs,
an
alternative
to
conventional
therapies,
emerges
a
promising
avenue
addressing
future
disease
challenges.
This
article
comprehensively
reviews
sources,
structural
characteristics,
synthesis,
degradation,
functions,
applications
polysaccharides.
The
pharmacological
applications,
antitumor,
antiaging,
antioxidant,
hypoglycemic,
anti‐inflammatory,
antiviral,
anticoagulant
is
summarized.
Additionally,
role
environmental
protection
discussed.
It
anticipated
that
this
review
will
offer
innovative
strategic
insights,
serving
theoretical
foundation
inspiration
subsequent
research
on
healthcare.
Applied Microbiology,
Год журнала:
2024,
Номер
4(1), С. 250 - 274
Опубликована: Янв. 23, 2024
Instances
of
inflammatory
bowel
disease
(IBD),
a
chronic
condition
the
gastrointestinal
tract,
are
rapidly
increasing
in
western
and
newly
industrialized
countries.
Exopolysaccharides
(EPSs)
one
strategies
to
enhance
gut
microbiota
modulate
immune-inflammatory
response
deregulation
IBD
patients.
EPSs
produced
by
commensal
bacteria
such
as
Lactobacillus
Bifidobacterium.
Additionally,
Cyanobacteria
species
promising
sources
novel
EPS
have
potential
pharmaceutical
therapeutic
applications.
The
presence
uronic
acids
sulphate
groups
Cyanobacterial
is
an
important
factor
that
gives
anionic
charge
not
seen
other
prokaryotic
species.
This
feature
may
impact
their
physico-chemical
characteristics
biological
properties.
wide
range
biotechnological
applications
include
use
thickeners,
stabilizers,
gelling
agents
food
sectors.
present
review
focuses
on
role
IBD,
with
special
focus
derived
from
Cyanobacteria.
also
covers
properties
immuno-inflammatory
responses
against
pathogens
well
its
Overall,
due
anti-inflammatory
immunoregulatory
can
reduce
inflammation
regulate
immune
restore
Tissue
repair
and
regeneration
are
critical
processes
for
maintaining
the
integrity
function
of
various
organs
tissues.
Recently,
polysaccharide
materials
protein
have
garnered
interest
use
in
tissue
strategies.
However,
polysaccharides
more
stable
unaffected
by
temperature
pH
changes
compared
to
proteins,
some
can
provide
stronger
mechanical
support,
which
is
particularly
important
constructing
tissue-engineered
scaffolds
wound
dressings.
This
Review
provides
an
in-depth
overview
origins
polysaccharides,
advantages
materials,
processing
design
In
addition,
potential
restoration
tissues
such
as
skin,
heart,
nerves
highlighted.
Finally,
we
discuss
depth
challenges
that
still
face
repair,
stability
material,
regulating
characteristics
deterioration
rates
under
different
conditions.
To
achieve
effective
regeneration,
future
research
must
focus
on
further
improving
functionalities
materials.
