Decoy oligonucleotides targeting NF-κB: a promising therapeutic approach for inflammatory diseases DOI
Maryam Mahjoubin‐Tehran, Samaneh Rezaei, Alexandra E. Butler

и другие.

Inflammation Research, Год журнала: 2025, Номер 74(1)

Опубликована: Март 6, 2025

Язык: Английский

A critical review on Lantana camara extract-mediated bio-inspired synthesis of nanomaterials and their potential application: Challenges and future perspectives DOI

Kajalben Patel,

Mamta Patil,

Yogita Abhale

и другие.

Inorganic Chemistry Communications, Год журнала: 2025, Номер 173, С. 113830 - 113830

Опубликована: Янв. 5, 2025

Язык: Английский

Процитировано

1

The critical role of nano-hydroxyapatites as an advanced scaffold in drug delivery towards efficient bone regeneration: Recent progress and challenges DOI Creative Commons

Amir Hatami kaleshtari,

Samira Farjaminejad,

Melika Hasani

и другие.

Carbohydrate Polymer Technologies and Applications, Год журнала: 2025, Номер unknown, С. 100692 - 100692

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

1

Bone tumor diagnosis: A FRET-based fluorescent osteocalcin sensor using palladium nanoparticles DOI
Tao Wang,

Ke Zhang,

Mingyang Jiang

и другие.

Alexandria Engineering Journal, Год журнала: 2025, Номер 120, С. 87 - 94

Опубликована: Фев. 11, 2025

Процитировано

1

Unveiling new frontiers in advancements of bio-inspired fabrication of cadmium-based nanomaterials for biomedical and catalytic applications – A review DOI

Kajalben Patel,

Mamta Patil,

Yogita Abhale

и другие.

Inorganic Chemistry Communications, Год журнала: 2024, Номер 170, С. 113457 - 113457

Опубликована: Ноя. 7, 2024

Язык: Английский

Процитировано

6

Determination of the solubility of methyldopa in supercritical carbon dioxide for drug delivery applications: thermal analysis DOI Creative Commons
Adil Farooq Wali, Sathvik Belagodu Sridhar, Sirajunisa Talath

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Янв. 6, 2025

The production of fine particles by green technology like supercritical carbon dioxide requires the assessment substantial solubility data at high pressures. This study represents first determination methyldopa in pressures and temperatures ranging from 12 to 30 MPa 313.2 343.2 K, respectively. mole fractions were obtained under aforementioned conditions ranged 0.805 × 10⁻5 11.345 10⁻5. Four empirical models (Chrastil, Bartle et al., Mendez-Santiago, & Teja, Kumar-Johnston) two equations state (Peng-Robinson Soave-Redlich-Kwong) used correlate drug solubility. K-J model demonstrated highest accuracy, with an AARD 8.38% a R2 value 0.988. Furthermore, enthalpy values for SC-CO₂ estimated using Chrastil models, resulting 34.35 56.87 kJ·mol⁻¹, results demonstrate that SRK more pronounced than PR model, AARD% 23.03 0.903 compared 26.42 0.837. article's conclusions provide valuable reference application method methyldopa.

Язык: Английский

Процитировано

0

Advancing mechanical and biological characteristics of polymer-ceramic nanocomposite scaffolds for sport injuries and bone tissue engineering: A comprehensive investigation applying finite element analysis and artificial neural network DOI

Fangbo Lin,

Ali Basem,

Mohammad H. Khaddour

и другие.

Ceramics International, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Mini-open transosseous repair with bursal augmentation improves outcomes in massive rotator cuff tears DOI Creative Commons
Yasser Safoury, Ahmed O. Sabry

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Янв. 17, 2025

Treatment of Massive rotator cuff tears (MRCT) is difficult, with high rates retears. Using biological augmentation in the form highly vascular subacromial bursa, was used to improve tendon healing. This work aimed evaluate results arthroscopic guided mini-open transosseous repair bursal treatment MRCTs a five-step approach. Forty-eight patients, mean age 63.15 years, were treated this technique. The patients evaluated constant, UCLA and VAS scores. Plain X-rays performed CSA MRI done confirm diagnosis MRCT determine degree fatty degeneration. Ultrasound at 1 year post-operative any follow-up period 29 months ± 4.95. Constant scores improved from (52.52) (89) (13.2) (30.5) respectively (p < 0.0001). active flexion abduction (112° 170°) (136.2° 167°) respectively, while ER (62.8° 70°) their p values Pain (5.85) (0.5) No deterioration function noted throughout period, no retears occurred on ultrasound evaluation. Mini-open an effective low-cost method that achieves satisfactory

Язык: Английский

Процитировано

0

Current update on surgical management for spinal tuberculosis: a scientific mapping of worldwide publications DOI Creative Commons

Romaniyanto Romaniyanto,

M. Ilyas,

Aldebaran Lado

и другие.

Frontiers in Surgery, Год журнала: 2025, Номер 11

Опубликована: Янв. 24, 2025

Introduction Spinal tuberculosis (TB), or Pott's disease, remains a significant global health issue, particularly in regions with high TB prevalence. Despite antitubercular drug therapy being the primary treatment, surgical intervention is often required cases of spinal instability neurological complications. This study aims to conduct comprehensive bibliometric analysis worldwide publications related management and compare contributions from orthopaedic surgery neurosurgery this field. Methods A was performed using data Scopus database, covering 1896 2024. The search strategy focused on terms interventions. included 1,857 publications, which were examined for trends, key contributors, evolution techniques. Metrics such as number leading authors, affiliations, countries, funding sponsors compared between neurosurgery. Results identified steady increase over time. Key topics evolved basic methods, including early procedures, integrating pharmacological approaches alongside techniques, drugs, advancing into imaging research procedure involving refined methods like fusion. recent phase reflects shift towards technology-driven approaches, minimally invasive artificial intelligence, machine learning. China emerged country most based author, sponsors, countries. Last, had more (274) than (96). Discussion In conclusion, has significantly, notable advanced, approaches. Orthopaedic leads output provides valuable insights landscape, guiding future studies TB.

Язык: Английский

Процитировано

0

Formulation and development of ACUPA-targeting PEGylated nanoliposomes for treatment of prostate cancer DOI

Seyedeh Alia Moosavian,

M. Amin, Seyedeh Hoda Alavizadeh

и другие.

Tissue and Cell, Год журнала: 2025, Номер 95, С. 102830 - 102830

Опубликована: Март 4, 2025

Язык: Английский

Процитировано

0

Organobase-catalyzed tandem green hemisynthesis of novel 1,4-naphthoquinone-chromene derivative from Ammodaucus leucotrichus (Cosson & Durieu) essential oil; antimicrobial activity and in silico exploration against psoriasis-associated receptors DOI
Ridha Hassaine, Nadia Taïbi, Ahmed Djafri

и другие.

Natural Product Research, Год журнала: 2025, Номер unknown, С. 1 - 6

Опубликована: Март 11, 2025

Chemical and biological properties of a novel 1,4-naphtoquinone-chromene derivative synthesised from perillaldehyde, major compound Ammodaucus leucotrichus essential oil were evaluated. The obtained product was efficiently prepared through tandem hemisynthesis reaction under environmentally friendly conditions (solvent-free, moderate temperature) via Knoevenagel condensation Michael addition reactions, using 4-pyrolidinopyridine organobase as catalyst. structure newly (HRP63) characterised FTIR,1H,13C 2D NMR spectroscopy. Furthermore, HRP63 assessed for its antimicrobial activity potential interaction with different receptors implicated in psoriasis. results revealed antibacterial activity. In silico molecular docking studies significant inhibitory against TNF-α, TLR7, TLR2, TNFR1 inhibition constants ranging 0.74 to 0.17 µM, free binding energies the complexes between −8.36 −9.24 kcal/M. These will guide future aimed at exploit pharmacological profile product.

Язык: Английский

Процитировано

0