Intracerebral delivery of the ionic liquid form of edaravone via nose-to-brain delivery route for treating cerebral ischemia/reperfusion injury DOI
Tatsuya Fukuta,

Kuniko Yoshimura,

Rikuto Ihara

и другие.

Journal of Controlled Release, Год журнала: 2025, Номер unknown, С. 113834 - 113834

Опубликована: Май 1, 2025

Язык: Английский

Adhesive Micro-Liquid for Efficient Removal of Bacterial Biofilm Infection DOI Creative Commons
Ying Wang, Zhi-Bang Li, Lingli Ji

и другие.

Materials Today Bio, Год журнала: 2025, Номер unknown, С. 101525 - 101525

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Microrheology of Ionic Liquid Doped Mucus for an Efficient Delivery of Protein‐Based Oral Drugs DOI Open Access
Nayanjyoti Kakati, Nabendu Paul, Saurabh Dubey

и другие.

Small, Год журнала: 2025, Номер unknown

Опубликована: Март 4, 2025

Abstract Developing protein‐based drugs for oral administration is one of the most challenging aspects research due to their low stability and inability permeate through intestinal mucus barrier. Recent studies suggest that ionic liquids (ILs) can combine with improve mucus‐penetration capabilities. However, interactions among drugs, ILs, mucin are rather unknown, which play a pivotal role in such drug delivery. The present work unveils molecular mechanisms delivery help microrheology experiments density functional theory (DFT) simulations. study employs model mesoscale system composed an IL, mucin, bovine serum albumin (BSA) as drug. In particular, following microrheological changes formulations helps tracing electrostatic, van der Waals, steric, hydrogen bonds, at various stages BSA, IL assemblage. results corroborated by morphological using atomic force microscopy supplemented diffusing‐wave‐spectroscopy. A human intestine has also been simulated biomimetic in‐vitro prototype demonstrate penetration BSA presence IL.

Язык: Английский

Процитировано

0
Dual-Functionality of CO2-Responsive Ionic Liquids for CO2 Storage: Fatty Acid Particles Re-precipitation and Clay Swelling Inhibition DOI
Xingyu Lin, Hongsheng Lu, Ruoxin Zhang

и другие.

Process Safety and Environmental Protection, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Ionic liquids as transdermal drug carriers: A review of recent advancements DOI

Rongtian Lin,

Jiaping Qian,

Jiaheng Zhang

и другие.

Journal of Molecular Liquids, Год журнала: 2025, Номер unknown, С. 127595 - 127595

Опубликована: Апрель 1, 2025

Процитировано

0
Intracerebral delivery of the ionic liquid form of edaravone via nose-to-brain delivery route for treating cerebral ischemia/reperfusion injury DOI
Tatsuya Fukuta,

Kuniko Yoshimura,

Rikuto Ihara

и другие.

Journal of Controlled Release, Год журнала: 2025, Номер unknown, С. 113834 - 113834

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0