Next Nanotechnology,
Год журнала:
2023,
Номер
2, С. 100018 - 100018
Опубликована: Июнь 1, 2023
6-Mercaptopurine
is
a
medication
employed
to
treat
autoimmune
illnesses
and
cancer.
However,
due
its
poor
solubility,
quick
metabolism,
possible
side
effects,
it
not
very
effective.
With
advantages
like
better
bioavailability,
increased
drug
stability,
targeted
deliveries,
nanomaterials
have
emerged
as
promising
platform
for
delivery.
This
article
addresses
the
possibility
of
treating
cancer
with
based
on
mercaptopurine.
Scientists
investigated
variety
treatments,
including
use
mercaptopurine,
since
disease
one
leading
causes
death
in
globe.
The
has
been
tested
an
adjuvant
treatment
colorectal
shown
cause
remission
patients
acute
lymphoblastic
leukemia.
Due
their
capacity
boost
uptake
by
cells,
protect
from
degradation,
lessen
toxicity
healthy
tissues,
liposomes,
dendrimers,
solid
lipid
nanoparticles
potential
mercaptopurine-based
nanomaterials,
gold
nanoparticles,
discussed
several
studies
reviewed
piece.
review
provides
researchers
latest
progress
6-mercaptopurine
loaded
nanocarriers
novel
approach
utilizing
delivery
Mercaptopurine
therapy
which
show
great
advanced
tool
compared
classic
mercaptopurine
drug.
OpenNano,
Год журнала:
2023,
Номер
15, С. 100197 - 100197
Опубликована: Ноя. 1, 2023
Cancer
is
amongst
the
foremost
causes
of
death
worldwide,
and
field
nanotechnology
presents
promising
prospects
in
terms
diagnostic
therapeutic
approaches.
Theranostics
are
nanoparticles
(NPs)
that
possess
ability
to
combine
capabilities
into
a
single
agent.
Nonetheless,
synthesis,
characterization,
delivery
NPs
for
theranostics
against
cancer
present
obstacles.
By
providing
swift,
responsive,
economical
platforms
detection
treatment,
microfluidic
systems
based
on
nanomaterials
can
overcome
these
A
synopsis
recent
developments
microfluidic-assisted
theranostic
nanosystems
treatment
various
malignancies
provided
this
mini-review.
In
addition
system-based
sensing
methods
(optical,
electrochemical,
mechanical,
thermal),
efficacious
approaches
(gene
therapy,
drug
delivery,
sonodynamic
etc.)
examined.
Further,
potential
limitations
innovative
technique
analyzed,
its
clinical
applications
future
proposed.
European Polymer Journal,
Год журнала:
2024,
Номер
216, С. 113267 - 113267
Опубликована: Июнь 27, 2024
Cancer
treatment
demands
innovative
approaches.
Azithromycin
(AZM),
traditionally
an
antibiotic,
shows
promise
in
inhibiting
cancer
growth
due
to
its
anti-inflammatory
and
senolytic
properties.
Beyond
antimicrobial
effects,
AZM
disrupts
mitochondrial
function
cells,
leading
increased
reactive
oxygen
species
(ROS)
DNA
damage.
This
cell
survival
pathways
induces
programmed
death.
has
shown
efficacy
against
various
cancers,
including
lung,
breast,
ovarian
cancers.
Nanoparticle
(NP)
delivery
systems
are
proposed
enhance
AZM's
therapeutic
potential.
NPs
offer
advantages
like
surface
area,
biocompatibility,
targeted
cells.
review
explores
strategies
for
using
nanomaterials,
polymers,
carbon-based
materials,
lipids,
inorganic
frameworks.
It
also
discusses
the
potential
of
combining
with
other
therapies.
Therapeutic Delivery,
Год журнала:
2023,
Номер
14(9), С. 595 - 613
Опубликована: Сен. 1, 2023
Cancer
disease
is
one
of
the
most
frequent
life-threatening,
with
a
high
fatality
rate
worldwide.
However,
recent
immunotherapy
studies
in
various
tumours
have
yielded
unsatisfactory
outcomes,
just
few
individuals
experiencing
long-term
responses.
To
overcome
these
issues,
nowadays
internal
stimuli-responsive
nanocarriers
been
widely
exploited
to
transport
wide
range
active
substances,
including
peptides,
genes
and
medicines.
These
nanosystems
could
be
chemically
adjusted
produce
target-based
drug
release
at
target
location,
minimizing
pathological
physiological
difficulties
while
increasing
therapeutic
efficiency.
This
review
highlights
types
applications
cancer
diagnosis.
study
can
provide
inspiration
impetus
for
exploiting
more
promising
delivery.
Next Nanotechnology,
Год журнала:
2023,
Номер
2, С. 100018 - 100018
Опубликована: Июнь 1, 2023
6-Mercaptopurine
is
a
medication
employed
to
treat
autoimmune
illnesses
and
cancer.
However,
due
its
poor
solubility,
quick
metabolism,
possible
side
effects,
it
not
very
effective.
With
advantages
like
better
bioavailability,
increased
drug
stability,
targeted
deliveries,
nanomaterials
have
emerged
as
promising
platform
for
delivery.
This
article
addresses
the
possibility
of
treating
cancer
with
based
on
mercaptopurine.
Scientists
investigated
variety
treatments,
including
use
mercaptopurine,
since
disease
one
leading
causes
death
in
globe.
The
has
been
tested
an
adjuvant
treatment
colorectal
shown
cause
remission
patients
acute
lymphoblastic
leukemia.
Due
their
capacity
boost
uptake
by
cells,
protect
from
degradation,
lessen
toxicity
healthy
tissues,
liposomes,
dendrimers,
solid
lipid
nanoparticles
potential
mercaptopurine-based
nanomaterials,
gold
nanoparticles,
discussed
several
studies
reviewed
piece.
review
provides
researchers
latest
progress
6-mercaptopurine
loaded
nanocarriers
novel
approach
utilizing
delivery
Mercaptopurine
therapy
which
show
great
advanced
tool
compared
classic
mercaptopurine
drug.
