An Electrochemical Immunosensor for Sensitive Detection of Exosomes Based on Au/MXenes and AuPtPdCu

Micromachines, Год журнала: 2025, Номер 16(3), С. 280 - 280

Опубликована: Фев. 27, 2025

Exosomes are important biomarkers for liquid biopsy in early cancer screening which play roles many biological processes, including apoptosis, inflammatory response, and tumor metastasis. In this study, an electrochemical aptamer immunosensor based on Au/MXene AuPtPdCu was constructed the sensitive detection of colorectal cancer-derived exosomes. AuNPs were deposited situ surface MXenes as a sensing platform due to their large specific area, excellent conductivity, higher number active sites immobilization. The CD63 immobilized can specifically capture target Therefore, AuPtPdCu-Apt nanoprobe further enhanced sensitivity accuracy immunosensor. A low limit 19 particles μL−1 achieved linear range 50 5 × 104 under optimal conditions. developed herein showed satisfactory stability anti-interference ability exosomes real serum samples.

Язык: Английский

Ameliorating the deleterious effect of water deficit stress on pomegranate through soil application of polyphenols-enriched extract from olive mill solid wastes

Journal of environmental chemical engineering, Год журнала: 2025, Номер unknown, С. 116442 - 116442

Опубликована: Март 1, 2025

Язык: Английский