Anti-inflammatory and skin improvement effect of a complex extract including Sophorae fruztus, Zingiber officinale, and Akebia quinata DOI

Dan-Hee Yoo,

Ji-Won Hur, Jung‐Wook Kang

и другие.

Deleted Journal, Год журнала: 2024, Номер 31(6), С. 1033 - 1042

Опубликована: Дек. 1, 2024

The purpose of this study was to investigate the effect on skin barrier improvement and anti-inflammatory effects using CSP-811 CSP-532 complex extracts mixed with 8:1:1 5:3:2 ratios Sophorae fructus, Zingiber officinale, Akebia quinata. experiment conducted by setting a concentration range that exhibited cell viability more than 95% in HaCaT RAW 264.7 cells. To determine improvement, expression levels filaggrin, involucrin, claudin-1, ZO-1 were measured As result, compared group treated only P. acnes, increased concentration-dependent manner. result measuring nitric oxide production inhibitory activity, decreased At final 1,000 μg/mL, both showed an 35% lipopolysaccharide alone treatment group. Afterward, as protein inducible NOS cyclooxygenase-2, confirmed at Therefore, it have effects, is judged excellent potential for use functional material.

Язык: Английский

Anti-inflammatory and skin improvement effect of a complex extract including Sophorae fruztus, Zingiber officinale, and Akebia quinata DOI

Dan-Hee Yoo,

Ji-Won Hur, Jung‐Wook Kang

и другие.

Deleted Journal, Год журнала: 2024, Номер 31(6), С. 1033 - 1042

Опубликована: Дек. 1, 2024

The purpose of this study was to investigate the effect on skin barrier improvement and anti-inflammatory effects using CSP-811 CSP-532 complex extracts mixed with 8:1:1 5:3:2 ratios Sophorae fructus, Zingiber officinale, Akebia quinata. experiment conducted by setting a concentration range that exhibited cell viability more than 95% in HaCaT RAW 264.7 cells. To determine improvement, expression levels filaggrin, involucrin, claudin-1, ZO-1 were measured As result, compared group treated only P. acnes, increased concentration-dependent manner. result measuring nitric oxide production inhibitory activity, decreased At final 1,000 μg/mL, both showed an 35% lipopolysaccharide alone treatment group. Afterward, as protein inducible NOS cyclooxygenase-2, confirmed at Therefore, it have effects, is judged excellent potential for use functional material.

Язык: Английский

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