Direct hybridization and bioinformatics analysis of circulating microRNAs in patients with Alzheimer’s disease under intravenous trehalose treatment

Brain Research, Год журнала: 2025, Номер unknown, С. 149607 - 149607

Опубликована: Апрель 1, 2025

Язык: Английский

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NOD-like receptor protein 3 inhibitors in St. John's wort and their potential antidepressant effects

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 306, С. 141721 - 141721

Опубликована: Март 3, 2025

Язык: Английский

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Immunomodulatory effects of Sanghuangporus flavonoids: Key insights into enhancing immunity and restoring immune function

International Immunopharmacology, Год журнала: 2025, Номер 153, С. 114474 - 114474

Опубликована: Март 21, 2025

Язык: Английский

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Immune Restoration Mechanism Analysis of Akkermansia PROBIO in Mice Treated with Cyclophosphamide through Re-balancing Microbiota Composition

Food Bioscience, Год журнала: 2025, Номер unknown, С. 106450 - 106450

Опубликована: Март 1, 2025

Язык: Английский

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Unveiling the dynamic migration and intrinsic relations between predominant bioactivities and metabolic profiles in persimmon leaves

Food Bioscience, Год журнала: 2025, Номер unknown, С. 106487 - 106487

Опубликована: Март 1, 2025

Язык: Английский

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Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of Trevesia Vis. (Araliaceae) with a Focus on Trevesia palmata : Review

Natural Product Communications, Год журнала: 2025, Номер 20(4)

Опубликована: Апрель 1, 2025

Trevesia Vis. species are small evergreen trees belonging to the family Araliaceae that occur naturally throughout Asia. The multiple parts of have been used in traditional medicinal systems several countries for their potential therapeutic properties, including pain relief, inflammation, fevers, microbial infections, diabetes, cancer, edema, bone fractures, and arthritis. This work presents a fascinating exploration previous studies on species, especially T. palmata , delving into phytochemical constituents, biological activities, toxicology, inviting you uncover further. paper database meticulously compiles valuable data gathered from all accessible literature between 1842 2024 through wide range resources, Web Science, Scopus, Google Scholar, PubMed, Science Direct, Springer, other scientific databases, ensuring comprehensive reliable overview research species. Various bioactive phytochemicals, such as triterpenoid saponins, flavonoids, phenolic compounds, found these plants. Chemotaxonomic investigations revealed genus may be closely related genera Aralia Acanthopanax Hedera . Pharmacological showed extracts phytocompounds exhibit various antiproliferative, anticancer, antibacterial, antifungal, antiviral, antioxidant, anti-inflammatory, antidiabetic, analgesic, thrombolytic, hepatoprotective activities. Moreover, numerous toxicological reports safety plant. For first time, this highlights role effects health benefits food medicine while also providing an current study status future prospects mainly

Язык: Английский

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Proteomic Insights into the Anti-Cancer Mechanisms of Boron-Based Compounds in Prostate Cancer

Food Bioscience, Год журнала: 2025, Номер unknown, С. 106558 - 106558

Опубликована: Апрель 1, 2025

Язык: Английский

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Plant-based antioxidant peptides: impact on oxidative stress and gut microbiota

Critical Reviews in Food Science and Nutrition, Год журнала: 2025, Номер unknown, С. 1 - 24

Опубликована: Апрель 12, 2025

Plant-based peptides can be obtained from natural and climate-friendly sources. These show various bioactivities including antioxidant activity. Oxidative stress has an impact on the gut microbiota causing inflammation, insulin resistance, osteoporosis, cancer, several chronic diseases like type 2 diabetes, arthritis, hypertension, atherosclerosis. Therefore, may significantly affect oxidative as a potential alternative to conventional medication. The production of plant-based protein sources through innovative approaches provide promising strategies improve microbiota. Recent studies in (PBAP) focus their advanced identification characterization techniques, structure-activity relationship, improvement extraction purification, cellular molecular mechanisms, specific health applications preventing managing conditions with microbiota, commercial nutraceuticals. Short-chain fatty acids reactive sulfur species are gut-derived metabolites that metabolic function by modulating immune system. This review highlights influence food oxidants PBAP-induced modulation Moreover, PBAP challenges application will discussed.

Язык: Английский

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Network pharmacology combined with transcriptomics reveals that Ganoderma lucidum spore and Sanghuangporus vaninii compound extract exerts anti-colorectal cancer effects via CYP24A1-mediated VDR pathway and TERT-mediated Wnt signaling pathway

Journal of Ethnopharmacology, Год журнала: 2025, Номер unknown, С. 119820 - 119820

Опубликована: Апрель 1, 2025

Язык: Английский

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Effects of Asiatic acid on brain cancer by altering astrocytes and the AKT1-PRKCB signaling pathway: A genomic and network pharmacology perspective

Brain Research, Год журнала: 2025, Номер unknown, С. 149652 - 149652

Опубликована: Апрель 1, 2025

Язык: Английский

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