Non-targeted screening of urban PM2.5 components based on cellular effects: influence from molecular features and sources DOI Open Access

P L Zhong,

Jinming Liu, Xinghua Qiu

и другие.

Journal of Environmental Exposure Assessment, Год журнала: 2025, Номер 4(2)

Опубликована: Апрель 11, 2025

Chemical composition plays a crucial role in the adverse health effects of fine particulate matter (PM2.5), yet traditional methods fail to comprehensively identify toxic components. In this study, we developed non-targeted approach using gas chromatography and high-resolution mass spectrometry, obtained database 2,138 organic components from PM2.5 samples collected urban Beijing between 2016 2018. Meanwhile, exposed extracts human lung epithelial cell line measured intracellular reactive oxygen species (ROS) extracellular cytokines as indicators cellular response. A combination single pollutant model, partial least squares regression, Bayesian kernel machine regression was applied filtered 165 robust database. Beyond 110 classic polycyclic aromatic compounds (PACs), also identified 14 anhydrides 21 nitrated contributors toxicity. Molecular features such unsaturation volatility were found be most significant factors influencing effects. Source apportionment analysis demonstrated distinct seasonal patterns toxicological impacts. During heating season, biomass burning emerged predominant pollution source, with its two-fold intensity elevation correlating 2.0% increase tumor necrosis factor (TNF)-α, accompanied by 6.0% 7.6% decreases vascular endothelial growth (VEGF) interleukin (IL)-8, respectively. contrast, non-heating season observations revealed vehicular emission principal contributor, inducing pronounced 11.0% ROS levels. This study introduces an effect-oriented for screening ambient PM2.5, offering valuable insights support formulation public protection strategies.

Язык: Английский

Evaluation of the cancer risk from PAHs by inhalation: Are current methods fit for purpose? DOI Creative Commons
Noel J. Aquilina, Roy M. Harrison

Environment International, Год журнала: 2023, Номер 177, С. 107991 - 107991

Опубликована: Май 23, 2023

There is ample evidence from occupational studies that exposure to a mixture of Polycyclic Aromatic Hydrocarbons (PAHs) causally associated with an increased incidence lung cancers. In both atmospheres and ambient air, PAHs are present as many compounds, but the composition in air differs atmosphere, varies time space air. Estimates cancer risk for PAH mixtures based upon unit risks which derive extrapolation data or animal model data, case WHO use one compound, benzo[a]pyrene marker entire mixture, irrespective composition. The U.S. EPA has used study inhalation alone, there have been number rankings relative carcinogenic potency other calculate frequently incorrectly by adding estimated individual applying total "B[a]P equivalent" risk, already applies mixture. Such often solely historic US group 16 compounds do not include apparently more potent carcinogens. no human PAHs, conflicting additivity carcinogenicity mixtures. This paper finds large divergences between estimates deriving methods, well considerable sensitivity composition, assumed potencies. Of two approach appears likely provide reliable estimates, recently proposed mixture-based approaches using vitro toxicity may offer some advantages.

Язык: Английский

Процитировано

39

Environmental impact assessment of multi-source solid waste based on a life cycle assessment, principal component analysis, and random forest algorithm DOI
Sichen Chen, Lu Yu, Chenmu Zhang

и другие.

Journal of Environmental Management, Год журнала: 2023, Номер 339, С. 117942 - 117942

Опубликована: Апрель 18, 2023

Язык: Английский

Процитировано

24

An update on adverse health effects from exposure to PM2.5 DOI Creative Commons
Sarawut Sangkham, Worradorn Phairuang, Samendra P. Sherchan

и другие.

Environmental Advances, Год журнала: 2024, Номер unknown, С. 100603 - 100603

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

12

Impact of Seasonal Heating on PM10 and PM2.5 Concentrations in Sučany, Slovakia: A Temporal and Spatial Analysis DOI Creative Commons
Dušan Jandačka, Daniela Ďurčanská, Miriam Nicolanská

и другие.

Fire, Год журнала: 2024, Номер 7(4), С. 150 - 150

Опубликована: Апрель 21, 2024

Complying with strict PM10 and PM2.5 limit values poses challenges in many European regions, influenced by diverse factors such as natural, regional, local anthropogenic sources. Urban air pollution, exacerbated road transport, industry, dust resuspension, contrasts rural areas affected solid fuel-based heating increasing wood burning. This study focuses on village of Sučany, located Slovakia, analysing PM concentrations during non-heating seasons. The method analysis relies the use MP101M quality analyser that utilises beta radiation absorption method. One set measurements was conducted at five distinct locations season (18/01/2019 to 28/02/2019) (14/08/2018 1/10/2018). Significant differences emerged corresponding averages 23.0 µg/m3 19.3 µg/m3. In contrast, averaged 53.9 52.8 season. shows contributing up 98% total PM10. distribution pollution location potential source obtained using polar plots differed research underscores impact a typical Slovak village. key recommendation for targeted interventions is supporting up-to-date data, education, financial incentives citizens order implement cleaner modern solutions.

Язык: Английский

Процитировано

10

Source-specific probabilistic exposure to PM2.5-bound trace elements in a school environment DOI
Jelena Obradović, Milena Jovašević-Stojanović,

Mario Obradović

и другие.

Building and Environment, Год журнала: 2025, Номер 270, С. 112509 - 112509

Опубликована: Янв. 5, 2025

Язык: Английский

Процитировано

2

NAT10 accelerates pulmonary fibrosis through N4-acetylated TGFB1-initiated epithelial-to-mesenchymal transition upon ambient fine particulate matter exposure DOI Creative Commons

Shenshen Wu,

Lijia Yin,

Ke Han

и другие.

Environmental Pollution, Год журнала: 2023, Номер 322, С. 121149 - 121149

Опубликована: Янв. 30, 2023

Язык: Английский

Процитировано

21

PM10 Resuspension of Road Dust in Different Types of Parking Lots: Emissions, Chemical Characterisation and Ecotoxicity DOI Creative Commons
Ismael Casotti Rienda, Célia Alves, Teresa Nunes

и другие.

Atmosphere, Год журнала: 2023, Номер 14(2), С. 305 - 305

Опубликована: Фев. 3, 2023

The thoracic fraction of road dust (PM10) was measured for the first time in Portugal parking areas, both outdoors and indoors, with aim completing existing studies carried out active lanes various roads. An situ resuspension chamber used to collect a total 23 samples three areas Aveiro, whilst laboratory procedures included determination carbonaceous content (OC EC) by thermo-optical technique, elemental composition ICP-MS ICP-OES after acid digestion, Aliivribrio fisherii bioluminescent bacteria ecotoxicity bioassay. Dust loadings (DL10) obtained were 18.5 ± 9.8 mg PM10 m−2, outdoor parking, 1.8–23.7 m−2 indoor corresponding emission factors 476 75–589 veh−1 km−1, respectively. OC represented 9–30 % areas. However, samples, high iron oxide jeopardised OC-EC separation. In those carbonates accounted 10.0 3.3% mass. analysis components focused on major elements (Al, Ca, Fe, K, Mg) as well minor elements. mass element oxides 27.1% (outdoor) 23.6–34.3% (indoor). ΣPAH calculated all 8.38–36.9 μg g−1 PM10. ecotoxicological bioassay showed that aqueous solutions toxic bacteria, whereas no clear correlations could be made specific component groups, exception EC50.

Язык: Английский

Процитировано

18

Respiratory deposition dose of PM2.5 and PM10 during night and day periods at an urban environment DOI Creative Commons
Yago Alonso Cipoli, Leonardo Furst, Manuel Feliciano

и другие.

Air Quality Atmosphere & Health, Год журнала: 2023, Номер 16(11), С. 2269 - 2283

Опубликована: Авг. 8, 2023

Abstract Inhalation of particulate matter (PM) has been extensively associated with the worsening and onset cardiorespiratory diseases, being responsible for millions deaths annually. Assessment PM deposition in human respiratory tract is critical to better understand health risks from environmental exposure vulnerable age groups. In this study, 2.5 10 day-night monitoring campaigns during cold season were carried out Bragança, Portugal. The multiple-path particle dosimetry (MPPD) model was used quantify total regional depositions four different groups: infant (3 months), child (9 years), adult (21 years) elderly (65 years). results showed that concentrations both fractions higher night, a period marked by burning biomass residential heating. Regional (DF) ranges 17–38% (head), 4–14% (tracheobronchial) 20–28% (pulmonary), while 24–67% 4–27% 12–22% (pulmonary). Children found be most groups deposition, especially TB H regions, respectively. lifetime cancer non-cancer exceeded recommended limits, children <10 years old. These findings provide useful information alert authorities need take action reduce pollution burden protect health, particular those susceptible. Graphical

Язык: Английский

Процитировано

18

Image based analytical approaches for study of particulate matter (PM) in air DOI Creative Commons
Ankesh Tiwari,

Mohineeta Pandey,

Astha Tirkey

и другие.

Frontiers in Environmental Science, Год журнала: 2024, Номер 12

Опубликована: Март 19, 2024

Particulate matter (PM) stands as a predominant pollutant in developing countries, demanding effective source identification and remediation strategies. This review centers on the scanning electron microscopy (SEM) image-based methodology for PM analysis, particularly emphasizing passive technique of utilizing plant leaves capture. The SEM-image-based approach serves powerful tool unraveling morphological characteristics PM, crucial identification. Additionally, SEM, when equipped with energy dispersive spectroscopy (EDS), enables chemical mineralogical characterization, providing insights into origin PM. first part describes best bio-sampler In this context, removal from environment through plant-based interventions is described. Subsequently, application SEM size-based analysis using ImageJ detailed. Following this, composition are described based EDS analysis. Image-based techniques play pivotal role selecting most species air. comprehensively outlines morphological, chemical, attributes utilized their subsequent by plants. Finally, benefits elucidated. offers holistic understanding SEM-EDS approach, presenting promising avenue addressing pollution enhancing environmental quality.

Язык: Английский

Процитировано

9

Eco-health risks and main sources of persistent pollutants bound by bus stops dust in Qingyang city, an important energy base on the west side of the Ziwuling primitive Forest DOI
Yongfu Wu,

Lianglu Hao,

Han Zhang

и другие.

Marine Pollution Bulletin, Год журнала: 2024, Номер 204, С. 116536 - 116536

Опубликована: Июнь 7, 2024

Язык: Английский

Процитировано

9