Analytical Sciences,
Год журнала:
2024,
Номер
40(12), С. 2181 - 2190
Опубликована: Авг. 28, 2024
A
straightforward
label-free
colorimetric
aptasensor
utilizing
the
aptamer-enhanced
peroxidase-like
activity
of
cobalt
oxyhydroxide
(CoOOH)
nanosheets
has
been
established
for
kanamycin
detection.
In
kanamycin-free
state,
aptamers
adsorb
onto
CoOOH
surface
through
electrostatic
forces,
enhancing
and
thereby
resulting
in
a
strong
absorption
signal
yellow
hue
3,3′,5,5′-tetramethylbenzidine
(TMB)
upon
termination
reaction
with
stop
solution.
Conversely,
introduction
kanamycin,
compete
binding
to
significant
decrease
number
bound
CoOOH.
As
result,
diminishes,
leading
corresponding
reduction
coloration
absorbance
Hence,
quantitative
determination
could
be
realized
by
analyzing
variations.
Under
optimal
conditions,
demonstrated
high
sensitivity
specificity,
linear
detection
range
from
500
nM
5
µM
limit
as
low
54.6
nM.
Moreover,
effectively
identified
river
water
samples,
achieving
recovery
rate
between
91.7%
102.1%.
This
approach
offers
good
practicability
provides
novel
platform
environmental
samples.
Analytical Chemistry,
Год журнала:
2024,
Номер
96(49), С. 19160 - 19182
Опубликована: Ноя. 27, 2024
This
Perspective
explores
the
revolutionary
advances
in
wearable
aptasensor
(WA)
technology,
which
combines
devices
and
aptamer-based
detection
systems
for
personalized,
real-time
health
monitoring.
The
leverage
specificity
sensitivity
of
aptamers
to
target
specific
molecules,
offering
broad
applications
from
continuous
glucose
tracking
early
diagnosis
diseases.
integration
data
analytics
artificial
intelligence
(AI)
allows
risk
prediction
guides
preventive
measures.
While
challenges
miniaturization,
power
efficiency,
security
persist,
these
hold
significant
potential
democratize
healthcare
reshape
patient-doctor
interactions.
Chemosensors,
Год журнала:
2025,
Номер
13(4), С. 141 - 141
Опубликована: Апрель 11, 2025
Aflatoxin
B1
(AFB1)
exhibits
high
toxicity
and
has
the
potential
to
induce
cancer,
deformities,
mutations.
It
is
therefore
highly
desirable
that
sensitive
straightforward
methods
for
detecting
AFB1
be
developed.
In
this
study,
due
specific
adsorption
capacity
of
aptamers,
we
applied
a
sensing
strategy
based
on
quantum
dots
(QDs)
carboxyl-functionalized
graphene
oxide
(FGO)
construct
simple
fluorescence
quenching
platform.
FGO
CdTe
QDs
modified
with
aptamers
cause
FRET
effect
produces
yellow-green
quenching.
When
present,
form
complexes
it
leave
platform,
resulting
in
recovery.
used
aptasensor
wide
detection
range
0.05
150
ng/mL
low
limit
(LOD)
8.2
pg/mL.
The
average
recoveries
peanut
pure
milk
samples
ranged
from
94.5%
107.0%.
also
exhibited
advantages
operation,
cost,
good
stability.
reported
here
can
thus
serve
as
candidate
rapid
AFB1.
RSC Advances,
Год журнала:
2025,
Номер
15(14), С. 11271 - 11282
Опубликована: Янв. 1, 2025
A
self-assembly
aptasensor
based
on
a
two-round
signal
amplification
strategy
for
kanamycin
trace
detection
was
demonstrated
by
employing
carbon
dot
decorated
Ti
3
C
2
MXene
as
electrode
modification
material
and
the
complex
of
double-stranded
DNA
(dsDNA)
methylene
blue
probes.
Molecules,
Год журнала:
2025,
Номер
30(9), С. 1951 - 1951
Опубликована: Апрель 28, 2025
Electrochemiluminescence
(ECL)/electrochemistry
(EC)
dual-mode
sensors
have
garnered
significant
interest
for
their
enhanced
analytical
reliability
through
the
cross-verification
of
dual-signal
outputs.
However,
conventional
approaches
necessitate
two
potential
scans
to
acquire
ECL
and
EC
signals
independently,
resulting
in
temporal
environmental
discrepancies
between
detection
modes.
In
this
paper,
we
present
a
novel
synchronous
ECL/EC
sensing
platform
lead
ion
(Pb2+)
via
one-step
scan
(0.2
-0.4
V
vs.
Ag/AgCl)
utilizing
G-quadruplex
(G4)-hemin
DNAzyme
complex.
This
complex
synergistically
catalyzed
electrochemical
reduction
dissolved
oxygen,
concurrently
generating
distinct
cathodic
emission
from
Ru(bpy)32+
current
peak
at
-0.25
V.
Pb2+
quantification
was
achieved
its
dose-dependent
suppression
activity
by
destabilizing
G4-hemin
interaction,
thereby
proportionally
attenuating
both
intensity
signal
(reduction
current).
The
integrated
sensor
demonstrated
high
sensitivity
(detection
limits
1.51
nM
2.03
detection),
robust
anti-interference
capability,
satisfactory
reproducibility,
with
recoveries
ranging
95.5
103.1%
water
analysis.
work
established
paradigm
design,
offering
new
prospects
monitoring.
Biosensors,
Год журнала:
2025,
Номер
15(5), С. 322 - 322
Опубликована: Май 18, 2025
Kanamycin
(KanR)
is
a
widely
used
antibiotic
in
human
and
veterinary
medicine,
as
well
food
production
livestock
breeding.
However,
its
environmental
residue
bioaccumulation
the
chain
pose
great
threat
to
health.
A
real-time
sensitive
aptasensor
developed
for
KanR
detection
based
on
gold
interdigitated
electrode
(IDE).
microfluidic
alternating
current
electrothermal
(ACET)
effect
employed
rapid
directional
manipulation
enrichment
of
molecules.
As
an
ultrasensitive
indicator,
solid–liquid
capacitance
adopted
reflect
tiny
change
IDE
surface
caused
by
target
adsorption.
The
overall
takes
only
60
s
from
sample
result,
wide
linear
range
0.1
fM~1
pM,
ultra-low
limit
16.56
aM,
high
selectivity
7752:1
are
simultaneously
achieved,
with
5
times
repeated
use
shelf
life
10
days.
Furthermore,
shows
excellent
practicability
milk
samples,
spiked
recovery
rate
ranging
86.90%
116.17%.
This
detecting
strategy
provides
rapid,
convenient,
cost-effective
solution
monitoring
KanR.
ACS Sensors,
Год журнала:
2024,
Номер
9(11), С. 5906 - 5914
Опубликована: Окт. 28, 2024
An
ultralow
cathodic
potential
electrochemiluminescence
(ECL)
aptasensor
was
designed,
employing
DNA
nanoribbon
template
self-assembly
copper
nanoclusters
(DNR-CuNCs)
as
a
novel
coreaction
accelerator
within
the
luminol-H
