Structural interaction relationship of six edible flavonoids with CYP3A4 based on spectroscopic and computer simulation DOI
Yutong Du, Meizi Wang, Yuan Li

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер unknown, С. 141297 - 141297

Опубликована: Дек. 1, 2024

Язык: Английский

Nutritional and functional assessment of haloarchaea and microalgae from the Andalusian shoreline: Promising functional foods with a high nutritional value DOI Creative Commons
Rosario Martínez,

Alejandro García Beltrán,

Garyfallia Kapravelou

и другие.

Journal of Functional Foods, Год журнала: 2024, Номер 116, С. 106194 - 106194

Опубликована: Апрель 22, 2024

Marine microbiota is garnering increasing interest as a potential source of novel foods with enhanced nutritional and functional properties. In this study, the proximate composition antioxidant capacity five haloarchaea microalgae species from Andalusian Atlantic shoreline (Halobacterium salinarum, Haloarcula hispanica, Dunaliella salina, C5 C13, Picochlorum spp) were compared to two freshwater (Chlamydomonas reinhardtii Chlorella sorokiniana). All studied exhibited high protein content activity, noticeable variations in total mineral fatty acid profile. Among four extraction methodologies tested prepare extracts, forced aqueous followed by hydrolysis resulted significantly greater yields while demonstrated higher activity present study. conclusion, diverse examined displayed value, showing great be part human diet rich sources readily available compounds.

Язык: Английский

Процитировано

6

A review on the utilization of the by-products generated during the production of Argan oil DOI Creative Commons
Otmane Hallouch, Mohamed Ibourki, Laila Bijla

и другие.

Journal of Agriculture and Food Research, Год журнала: 2025, Номер unknown, С. 101770 - 101770

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Argan Fruit Polyphenols Regulate Lipid Homeostasis, Prevent Liver Fat Accumulation, and Improve Antioxidant Defense in High-Calorie Diet Fed Mice: In Vivo Study and In Silico Prediction of Possible Underlying Mechanisms DOI Creative Commons
Mohammadine Moumou,

Imane Mokhtari,

Mohamed Harnafi

и другие.

Metabolites, Год журнала: 2025, Номер 15(4), С. 234 - 234

Опубликована: Март 28, 2025

Background/Objectives: Argania spinosa L. Skeels is a Moroccan endemic plant widely used by the local population as folk medicine. This study aimed to investigate effects of Argan fruit pulp on lipid metabolism disorders and liver steatosis in hypercaloric diet-fed mice. Methods: Animals were treated with extract its fractions for 12 weeks at 100 200 mg Kg−1 BW daily. The analysis was conducted levels plasma, liver, feces, bile well glycemia. glutathione, malondialdehyde, antioxidant enzyme activities assessed. hepatic evaluated measuring transaminases alkaline phosphatase examining histological sections. polyphenol profiles determined using HPLC-DAD. Possible underlying mechanisms hypolipidemic hepatoprotective predicted molecular docking. Results: crude aqueous fraction (rich protocatechuic gallic acids) significantly restored plasma lipids glucose levels. Indeed, total cholesterol level (TCHO) decreased but increased feces. treatment also reduced body weight adipose tissue mass prevented steatosis. ethyl acetate exhibited no effect oxidative stress. appear be nontoxic (LD50 > 5000 Kg−1) phenolic acids demonstrated strong binding affinity key targets involved regulating homeostasis, including ABCA-1, LXR, CYP7A1, HMH-CoA reductase, PCSK-9. However, identified flavonoids high affinities stress defense (SOD, CAT, CYP2E1). Conclusions: pulp, particularly polyphenols, could promising natural approach preventing cardio-metabolic diseases improving reducing

Язык: Английский

Процитировано

0

A Novel Plant-Based Nutraceutical Combined with Exercise Can Revert Oxidative Status in Plasma and Liver in a Diet-Induced-Obesity Animal Model DOI Creative Commons
Ana Guzmán, Garyfallia Kapravelou,

María López‐Jurado

и другие.

Antioxidants, Год журнала: 2024, Номер 13(3), С. 274 - 274

Опубликована: Фев. 23, 2024

The prevalence of obesity increases alarmingly every year mostly due to external factors such as high-fat and high-refined sugar intake associated with a sedentary lifestyle. It triggers metabolic disorders insulin resistance, hyperlipemia, non-alcoholic fatty liver disease, chronic inflammation, oxidative stress, gut microbiota dysbiosis. aim this study was evaluate the beneficial effects combined intervention caloric restriction, nutraceutical intake, mixed training protocol on dysbiosis derived from development in C57BL6/J mouse experimental model diet-induced (4.6 Kcal/g diet, 45% Kcal fat, 20% fructose drinking fluid). formulated ethanolic extracts Argania spinosa pulp (10%) Camelina sativa seeds protein hydrolysates Psoralea corylifolia (40%) Spirodela polyrhiza whole plants (40%). combination exercise decreased animals’ body weights inflammatory markers (TNFα, IL-6, resistin) plasma, while increasing gene expression cat, sod2, gsta2, nqo1 liver. Obese animals showed lower β-diversity higher Firmicutes/Bacteroidetes ratio vs. normocaloric controls that were reversed by all interventions implemented. Dietary inclusion high antioxidant potential an can be for bodyweight control improvement status patients undergoing treatment.

Язык: Английский

Процитировано

3

A Comparative Evaluation of the Physico- and bio-chemical Characteristics and Antioxidant Activities of Six Argan ((Argania Spinosa (L.) Skeels)) Varieties DOI Creative Commons
Abderrahim Asbbane, Mohamed Ibourki, Otmane Hallouch

и другие.

Journal of Agriculture and Food Research, Год журнала: 2024, Номер unknown, С. 101582 - 101582

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

2

Ultrasonic assisted extraction of oil from argan seeds using ionic liquids as novel co-solvent DOI
Maan Hayyan, Khalid M. Abed, Maan Hayyan

и другие.

Biomass Conversion and Biorefinery, Год журнала: 2024, Номер unknown

Опубликована: Июнь 27, 2024

Язык: Английский

Процитировано

1

The Importance of Argan Oil in Medicine and Cosmetology DOI Open Access
Agata Serrafi, Fatima Chegdani,

Faïza Bennis

и другие.

Nutrients, Год журнала: 2024, Номер 16(20), С. 3573 - 3573

Опубликована: Окт. 21, 2024

Argan oil, rich in unsaturated fatty acids and polyphenols, exerts beneficial effects on both the intestinal skin microbiotas. In gut, it promotes growth of bacteria, such as

Язык: Английский

Процитировано

1

Structural interaction relationship of six edible flavonoids with CYP3A4 based on spectroscopic and computer simulation DOI
Yutong Du, Meizi Wang, Yuan Li

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер unknown, С. 141297 - 141297

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

1