Nutrients, Год журнала: 2025, Номер 17(5), С. 762 - 762
Опубликована: Фев. 21, 2025
Objectives: This systematic review investigates the effectiveness of natural extracts with anti-inflammatory properties for improving oral health, particularly in managing gingivitis and periodontal disease (PD). With PD being a major global health issue, exacerbated by microbial dysbiosis oxidative stress, integration phytochemicals herbal formulations into therapy offers promising avenue adjunctive treatments. Methods: A was conducted following PRISMA guidelines registered under International Prospective Register Systematic Reviews (ID: 641944). Databases, including PubMed, Scopus, Web Science, were searched between 18–24 December 2024, using Boolean keywords combining terms such as “herbal medicine”, “plant extracts”, “anti-inflammatory”, “periodontal therapy”. Studies involving animal models, vitro data, or non-peer-reviewed articles excluded. Results: Seventeen studies met inclusion criteria. Polyherbal single-component (e.g., Camellia sinensis, Punica granatum, Zingiber officinale, Rosmarinus officinalis) demonstrated comparable efficacy to conventional agents like chlorhexidine (CHX). rinses, camellia sinensis gels, granatum reduced inflammation, improved gingival showed antimicrobial properties, offering effective alternatives. Conclusions: Natural products, single polyherbal formulations, provide safe alternatives PD. Their anti-inflammatory, antimicrobial, antioxidant support their role alongside scaling root planning (SRP) therapy. However, further large-scale, long-term are needed standardize establish optimal protocols.
Язык: Английский