Trends in the development of immunoassays for mycotoxins and food allergens using gold and carbon nanostructured material DOI Creative Commons
Shyang Pei Hong, Siti Nurul Azian Zakaria, Minhaz Uddin Ahmed

и другие.

Food Chemistry Advances, Год журнала: 2022, Номер 1, С. 100069 - 100069

Опубликована: Июль 17, 2022

Mycotoxins and food allergens are growing health concerns in the area of safety. Accidental exposure to mycotoxins can arise many ways including allergenic proteins due cross-contamination, unspecified product labels toxic residues through direct or indirect intake contaminated food. In recent years, nanomaterials various immunoassays have shown great potential selectively detect with lower detection limits a shorter time. This review compares different immunoassay approaches, discusses applications carbon gold developing allergens. Various types shapes carbon, spherical non-spherical nanoparticles their synthesis methods were elaborated. The approaches on how these be incorporated used as combination improve performance addressed. Lastly, challenges prospects contaminants discussed.

Язык: Английский

Advances in immunoassay‐based strategies for mycotoxin detection in food: From single‐mode immunosensors to dual‐mode immunosensors DOI
Mengting Chen, Aori Qileng,

Hongzhi Liang

и другие.

Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2023, Номер 22(2), С. 1285 - 1311

Опубликована: Янв. 30, 2023

Abstract Mycotoxin contamination in foods and other goods has become a broad issue owing to serious toxicity, tremendous threat public safety, terrible loss of resources. Herein, it is necessary develop simple, sensitive, inexpensive, rapid platforms for the detection mycotoxins. Currently, limitation instrumental chemical methods cannot be massively applied practice. Immunoassays are considered one best candidates toxin due their simplicity, rapidness, cost‐effectiveness. Especially, field dual‐mode immunosensors corresponding assays rapidly developing as an advanced intersected technology. So, this review summarized types principles single‐mode including optical electrical recent years, then focused on integrated combined detect mycotoxins, well combination with portable device point‐of‐care test. The remaining challenges were discussed aim stimulating future development accelerate transformation scientific laboratory technologies into easy‐to‐operate platforms.

Язык: Английский

Процитировано

59

MXene-based aptasensor for the detection of aflatoxin in food and agricultural products DOI Open Access
Arpana Parihar,

Nishant Kumar Choudhary,

Palak Sharma

и другие.

Environmental Pollution, Год журнала: 2022, Номер 316, С. 120695 - 120695

Опубликована: Ноя. 21, 2022

Язык: Английский

Процитировано

50

Dual-layers Raman reporter-tagged Au@Ag combined with core-satellite assemblies for SERS detection of Zearalenone DOI
Limei Yin, Tianyan You, Muhammad Arslan

и другие.

Food Chemistry, Год журнала: 2023, Номер 429, С. 136834 - 136834

Опубликована: Июль 11, 2023

Язык: Английский

Процитировано

41

Applications of advanced materials in the pretreatment and rapid detection of small molecules in foods: A review DOI

Zhizhou Ling,

Jinyi Yang, Yongyi Zhang

и другие.

Trends in Food Science & Technology, Год журнала: 2023, Номер 141, С. 104175 - 104175

Опубликована: Сен. 22, 2023

Язык: Английский

Процитировано

38

Ratiometric Detection of Ochratoxin A Using a Regenerable COF-Au-MB-Apt Signal Probe on a Thermal-Regulated Sensor Module DOI
Xuan Zhou, Zongbao Sun, Xiaoyu Su

и другие.

Analytical Chemistry, Год журнала: 2023, Номер 95(3), С. 1916 - 1923

Опубликована: Янв. 9, 2023

Ochratoxin A (OTA) frequently contaminates grains and consequently threatens human health. Herein, we develop a regenerable signal probe apply it to Au-based screen-printed electrode module (SPE) for OTA determination. The probe, containing structural covalent organic framework, gold nanoparticles (AuNPs), indicative methylene blue (MB), highly selective aptamer, is synthesized with hydrothermal self-assembly methods. SPE permanently functionalized Prussian (PB), AuNPs, semicomplementary ssDNA. absorbed onto this via hybridization, competitively expelled by OTA, providing ratiometric readout of ΔIMB/IPB. Probe regeneration, erase expired COF-Au-MB-Apt after each analysis, established the synergy OTA-conducted Apt-ssDNA dissociation on-chip thermal regulation. This advantage powerfully guarantees reduplicative analyses avoiding irreversible Apt-OTA combination accumulation on sensing interface. Regenerations are performed in repetitive cycles (N = 7) 98.5% reproduction efficiency, IMB IPB fluctuations calculated as 1.45 1.12%. method shows log-linear response wide range from 0.2 pg/mL 0.6 μg/mL, limit detection 0.12 pg/mL. During natural determinations, recommended readouts match well HPLC less than 4.82% relative error.

Язык: Английский

Процитировано

33

CRISPR/Cas-based nanobiosensors: A reinforced approach for specific and sensitive recognition of mycotoxins DOI

Ma Haowei,

Shadi Ebrahimi, Sofiène Mansouri

и другие.

Food Bioscience, Год журнала: 2023, Номер 56, С. 103110 - 103110

Опубликована: Сен. 9, 2023

Язык: Английский

Процитировано

30

Magnetic nanoparticle‐based immunosensors and aptasensors for mycotoxin detection in foodstuffs: An update DOI
Shipeng Gao,

Ruiyun Zhou,

Di Zhang

и другие.

Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2023, Номер 23(1)

Опубликована: Дек. 13, 2023

Abstract Mycotoxin contamination of food crops is a global challenge due to their unpredictable occurrence and severe adverse health effects on humans. Therefore, it great importance develop effective tools prevent the accumulation mycotoxins through chain. The use magnetic nanoparticle (MNP)‐assisted biosensors for detecting mycotoxin in complex foodstuffs has garnered interest significantly enhanced sensitivity accuracy. Within such context, this review includes fundamentals recent advances (2020–2023) area monitoring matrices using MNP‐based aptasensors immunosensors. In review, we start by providing comprehensive introduction design immunosensors (natural antibody or nanobody, random site‐oriented immobilization) (techniques aptamer selection, characterization, truncation). Meanwhile, special attention paid multifunctionalities MNPs (recoverable adsorbent, versatile carrier, signal indicator) preparing mycotoxin‐specific biosensors. Further, contribution multiplexing determination various summarized. Finally, challenges future perspectives practical applications MNP‐assisted are also discussed. progress updates shown expected offer readers valuable insights about detection applications.

Язык: Английский

Процитировано

24

Highly Sensitive Microarray Immunoassay for Multiple Mycotoxins on Engineered 3D Porous Silicon SERS Substrate with Silver Nanoparticle Magnetron Sputtering DOI
Jing Yang, Wei Li, Hao Li

и другие.

Analytical Chemistry, Год журнала: 2024, Номер 96(6), С. 2425 - 2434

Опубликована: Янв. 31, 2024

A high-throughput, rapid, and highly sensitive surface-enhanced Raman spectroscopy (SERS) microarray for screening multiple mycotoxins has been developed on a three-dimensional silver nanoparticle porous silicon (3D AgNP-Psi) SERS substrate, which was easy to be engineered by electrochemical etching magnetron sputtering technology. The current density, waveform, target material have investigated obtain an optimal 3D substrate. optimized AgNP-Psi substrate showed enhancement factor of 2.3 × 107 at 400 mA/cm2 constant density 20 s Ag 200 nm thickness the surface Psi. simulation electric field distribution near-field can reach 3× higher than that AuNPs. protein designed screen AuNP tags competitive immunoassay protocol displayed wide linear detection ranges 0.001–100 ng/mL ochratoxin A, 0.01–100 aflatoxin B1, 0.001–10 deoxynivalenol, along with pg/mL low limit detection, good recovery rates, repeatability, reproducibility. is easily great potential application in medicine, environment, food industry fields.

Язык: Английский

Процитировано

17

Nafion-Immobilized Functionalized MWCNT-based Electrochemical Immunosensor for Aflatoxin B1 Detection DOI Creative Commons
Kai Deng,

Zhang Yining,

Hang Xiao

и другие.

ACS Omega, Год журнала: 2024, Номер 9(8), С. 8754 - 8762

Опубликована: Фев. 13, 2024

The ubiquitous aflatoxin B1 (AFB1) contamination in foods and other complex matrices has brought great challenges for onsite monitoring. In this study, an ultrasensitive Nafion-immobilized functionalized multiwalled carbon nanotube (MWCNT)-based electrochemical (EC) immunosensor was developed trace AFB1 detection. introduced Nafion film could steadily stabilize MWCNTs with uniform distribution tiling on the surface of a Au electrode. Functionalized large specific area, numerous active sites to couple abundant anti-AFB1 monoclonal antibodies (mAbs), high conductivity served as signal amplifier remarkably enhancing sensing performance immunosensor. presence AFB1, it specifically captured by mAbs reduce amplified current signals, which were recorded differential pulse voltammetry accurate quantitation AFB1. Because synergistic effects stabilization enhancers, EC exhibited extremely selectivity, excellent sensitivity limit detection low 0.021 ng/mL, wide dynamic range 0.05–100 besides fascinating merits easy construction, cost, good stability 7 days, reusability. anti-interference ability verified against three mycotoxins, practicability accuracy confirmed measuring fortified malt, lotus seed, hirudo samples satisfactory recovery 92.08–104.62%. This novel immunosensing platform be extended detect more mycotoxins ensure food safety.

Язык: Английский

Процитировано

13

Ready-to-use ratiometric bioluminescence immunosensor for detection of ochratoxin a in pepper DOI

Xiaoxia Xie,

Xun Yang,

Yongli Zhang

и другие.

Biosensors and Bioelectronics, Год журнала: 2024, Номер 259, С. 116401 - 116401

Опубликована: Май 15, 2024

Язык: Английский

Процитировано

11