Co-exposure with cadmium elevates the toxicity of microplastics: Trojan horse effect from the perspective of intestinal barrier

Journal of Hazardous Materials, Год журнала: 2024, Номер 466, С. 133587 - 133587

Опубликована: Янв. 22, 2024

Язык: Английский

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Exposure to 6-PPD quinone causes ferroptosis activation associated with induction of reproductive toxicity in Caenorhabditis elegans

Journal of Hazardous Materials, Год журнала: 2024, Номер 471, С. 134356 - 134356

Опубликована: Апрель 19, 2024

Язык: Английский

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The hidden threat: Unraveling the impact of microplastics on reproductive health

The Science of The Total Environment, Год журнала: 2024, Номер 935, С. 173177 - 173177

Опубликована: Май 13, 2024

Язык: Английский

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Polystyrene nanoplastics and cadmium co-exposure aggravated cardiomyocyte damage in mice by regulating PANoptosis pathway

Environmental Pollution, Год журнала: 2024, Номер 347, С. 123713 - 123713

Опубликована: Март 8, 2024

Язык: Английский

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Unveiling the impacts of microplastics on cadmium transfer in the soil-plant-human system: A review

Journal of Hazardous Materials, Год журнала: 2024, Номер 477, С. 135221 - 135221

Опубликована: Июль 18, 2024

Язык: Английский

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Co-exposure of decabromodiphenyl ethane and cadmium increases toxicity to earthworms: Enrichment, oxidative stress, damage and molecular binding mechanisms

Journal of Hazardous Materials, Год журнала: 2024, Номер 473, С. 134684 - 134684

Опубликована: Май 21, 2024

Язык: Английский

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Ferroptosis induced by environmental pollutants and its health implications

Cell Death Discovery, Год журнала: 2025, Номер 11(1)

Опубликована: Янв. 24, 2025

Abstract Environmental pollution represents a significant public health concern, with the potential risks associated environmental pollutants receiving considerable attention over an extended period. In recent years, substantial body of research has been dedicated to this topic. Since discovery ferroptosis, iron-dependent programmed cell death typically characterized by lipid peroxidation, in 2012, there have advances study its role and mechanism various diseases. A growing number studies also demonstrated involvement ferroptosis damage caused organism pollutants, molecular mechanisms involved partially elucidated. The targeting be effective means ameliorating PM2.5, organic inorganic ionizing radiation. This review begins providing summary most important ferroptosis. It then proceeds offer critical analysis effects induced pollutants. Furthermore, as is case all rapidly evolving areas, are numerous unanswered questions challenges pertaining pollutant-induced which we discuss attempt provide some directions clues for future field.

Язык: Английский

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Microplastic-induced NAFLD: Hepatoprotective effects of nanosized selenium

Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 272, С. 115850 - 115850

Опубликована: Янв. 30, 2024

Polystyrene microplastics (MPs) are persistent environmental pollutants commonly encountered in daily human life. Numerous studies have demonstrated their ability to induce liver damage, including oxidative stress, inflammation, and lipid accumulation. However, limited information exists regarding preventive measures against this issue. In our study, we investigated the potential role of selenium nanoparticles (YC-3-SeNPs) derived from Yak-derived Bacillus cereus, a novel nanobiomaterial known for its antioxidant properties metabolism regulation. Using transcriptomic metabolomic analyses, identified key genes metabolites associated with stress imbalance induced by MPs. Upregulated (Scd1, Fasn, Irs2, Lpin) elevated levels arachidonic palmitic acid accumulation were observed MP-exposed mice, but not those exposed SeNPs. Further experiments confirmed that SeNPs significantly attenuated degeneration caused Histological results pathway screening validated findings, revealing MPs suppressed Pparα Nrf2 pathway, whereas activated both pathways. These findings suggest may contribute development nonalcoholic fatty disease (NAFLD), while hold promise as future nanobio-product prevention.

Язык: Английский

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Combined exposure of PS-MPs with NaF induces Sertoli cell death and dysfunction via ferroptosis and apoptosis

Toxicology, Год журнала: 2024, Номер 506, С. 153849 - 153849

Опубликована: Май 29, 2024

Язык: Английский

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Adverse effects and potential mechanisms of polystyrene microplastics (PS-MPs) on the blood-testis barrier

Environmental Geochemistry and Health, Год журнала: 2024, Номер 46(7)

Опубликована: Июнь 7, 2024

Язык: Английский

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