Recent advances in active packaging: Insights into novel functional elements, response strategies and applications for food preservation
Food Packaging and Shelf Life,
Год журнала:
2025,
Номер
49, С. 101489 - 101489
Опубликована: Апрель 4, 2025
Язык: Английский
Quantification of elemental composition of the thin tissue slices with the commercial benchtop micro-XRF spectrometer
Measurement,
Год журнала:
2024,
Номер
unknown, С. 115939 - 115939
Опубликована: Окт. 1, 2024
Язык: Английский
Genome-wide DNA methylation sequencing reveals the involvement of ferroptosis in hepatotoxicity induced by dietary exposure to food-grade titanium dioxide
Particle and Fibre Toxicology,
Год журнала:
2024,
Номер
21(1)
Опубликована: Сен. 18, 2024
Язык: Английский
The Genetic and Epigenetic Toxicity of Silica Nanoparticles: An Updated Review
Manjia Zheng,
Ziwei Chen,
Jiling Xie
и другие.
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 13901 - 13923
Опубликована: Дек. 1, 2024
Silica
nanoparticles
(SiNPs)
are
widely
used
in
biomedical
fields,
such
as
drug
delivery,
disease
diagnosis,
and
molecular
imaging.
An
increasing
number
of
consumer
products
containing
SiNPs
being
without
supervision,
the
toxicity
to
human
body
is
becoming
a
major
problem.
contact
various
ways
cause
damage
structure
function
genetic
material,
potentially
leading
carcinogenesis,
teratogenicity
infertility.
This
review
summarizes
SiNPs-induced
epigenetic
toxicity,
especially
germ
cells,
explore
their
potential
mechanisms.
material
mainly
by
inducing
oxidative
stress.
Furtherly,
mechanisms
discussed
detail
for
first
time.
alter
DNA
methylation,
miRNA
expression,
histone
modification
inhibit
chromatin
remodeling
regulating
epigenetic-related
enzymes
transcription
factors.
beneficial
investigating
solutions
avoid
provide
guidance
better
application
field.
Язык: Английский
Taurine Protects against Silica Nanoparticle-Induced Apoptosis and Inflammatory Response via Inhibition of Oxidative Stress in Porcine Ovarian Granulosa Cells
Animals,
Год журнала:
2024,
Номер
14(20), С. 2959 - 2959
Опубликована: Окт. 14, 2024
Silica
nanoparticles
(SNPs)
induce
reproductive
toxicity
through
ROS
production,
which
significantly
limits
their
application.
The
protective
effects
of
taurine
(Tau)
against
SNP-induced
remain
unexplored.
So
this
study
aims
to
investigate
the
impact
Tau
on
porcine
ovarian
granulosa
cell
toxicity.
In
vitro,
cells
were
exposed
SNPs
combined
with
Tau.
localization
was
determined
by
TEM.
Cell
viability
examined
CCK-8
assay.
levels
measured
CLSM
and
FCM.
SOD
CAT
evaluated
using
ELISA
qPCR.
apoptosis
detected
FCM,
pro-inflammatory
cytokine
transcription
results
showed
that
decreased
viability,
while
increased
levels.
Moreover,
decreased,
IFN-α,
IFN-β,
IL-1β,
IL-6
after
SNP
exposures.
intracellular
ROS,
it
compared
alone.
Additionally,
exhibited
anti-inflammatory
inhibited
apoptosis.
On
whole,
these
findings
suggest
mitigates
cytotoxicity
reducing
oxidative
stress,
inflammatory
response,
may
be
an
effective
strategy
alleviate
holds
promising
application
prospects
in
animal
husbandry
veterinary
industry.
Язык: Английский
Re‐evaluation of silicon dioxide (E 551) as a food additive in foods for infants below 16 weeks of age and follow‐up of its re‐evaluation as a food additive for uses in foods for all population groups
EFSA Journal,
Год журнала:
2024,
Номер
22(10)
Опубликована: Окт. 1, 2024
The
present
opinion
is
the
follow-up
of
conclusions
and
recommendations
Scientific
Opinion
on
re-evaluation
silicon
dioxide
(E
551)
as
a
food
additive
relevant
to
safety
assessment
for
all
age
groups.
In
addition,
risk
its
use
in
infants
below
16
weeks
performed.
Based
newly
available
information
characterisation
SAS
used
E
551
following
principles
2021
EFSA
Guidance
Particle-TR,
conventional
has
been
complemented
with
nano-specific
considerations.
Given
uncertainties
resulting
from
limitations
database
absence
genotoxicity
concern,
Panel
considered
that
it
not
appropriate
derive
an
acceptable
daily
intake
(ADI)
but
applied
margin
exposure
(MOE)
approach
assessment.
concluded
MOE
should
be
at
least
36
raising
concern.
calculated
MOEs
considering
dietary
estimates
population
groups
using
refined
non-brand
loyal
scenario,
estimated
time
2018
re-evaluation,
were
above
36.
does
raise
concern
reported
uses
levels.
FC
13.1.1
13.1.5.1
current
also
technical
data
provided
support
amendment
specifications
laid
down
Commission
Regulation
(EU)
No
231/2012.
paucity
toxicological
studies
proper
dispersion
protocol
(with
exception
studies)
creates
uncertainty
potential
effects
related
nanosize
aggregates.
Язык: Английский