Frontiers in Chemistry,
Год журнала:
2025,
Номер
12
Опубликована: Янв. 15, 2025
Microorganisms
are
becoming
resistant
to
drugs
and
antimicrobials,
making
it
a
significantly
critical
global
issue.
Nosocomial
infections
resulting
in
alarmingly
increasing
rates
of
morbidity
mortality.
Plant
derived
compounds
hold
numerous
antimicrobial
properties,
them
very
capable
source
counteract
microbial
strains.
Syzygium
aromaticum
(Clove)
extract
has
been
proven
by
studies
contain
active
ingredients
that
demonstrate
antibacterial,
antifungal,
antioxidant,
insecticidal
properties.
It
also
used
historically
for
its
pain
relief
especially
tooth
ache.
Clove
nanoparticle
synthesis
is
promising
method
combining
therapeutics
with
metals
at
nanoscale.
Such
nanostructured
systems
combination
the
heterocyclic
antibiotic
clarithromycin
could
potentiate
action
plant
extracts,
decrease
drug
side
effects
improve
activity.
In
this
study,
clove
(C)
was
successfully
synthesize
silver
nanoparticles
(AgNP)
create
AgNPC
AgNPCA
(A
=
clarithromycin).
The
two
underwent
different
analytical
methods
consisting
SEM,
EDS,
DLS,
UV-vis,
FTIR
XRD.
These
were
against
variety
10
pathogens
exhibited
good
intermediate
antibacterial
resulted
better
properties
smaller
size.
This
study
demonstrates
potential
mediated
AgNP
without
clarithromycin.
