Microplastics in aquatic ecosystems: Detection, source tracing, and sustainable management strategies

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 291, С. 117883 - 117883

Опубликована: Фев. 1, 2025

Microplastics (MPs) are emerging contaminants characterized by persistence, cross-media transport, and complex pollutant interactions, posing serious ecotoxicological risks to ecosystems human health. Effective MPs management requires multi-faced, long-term, strategies involving targeted sampling, quantitative detection, comprehensive risk assessments, all of which entail significant resource investment. Despite advancements in remediation technologies, a holistic governance framework integrating these innovations remains underdeveloped. This review synthesizes current knowledge on MPs, elaborating their diverse morphologies, degradation pathways, role as vectors for toxic substances. State-of-the-art extraction techniques evaluated this article, including micropore adsorption using nanocomposites, alongside the incorporation advanced analytical tools such spectroscopic methods, electron microscopy, bioinformatics augment environmental forensics. also underscores necessity formulating robust global policies regulate pollution discusses potential biodegradation thermal sustainable solutions removal. By promoting an interdisciplinary approach, advocates coordinated response, science, policy frameworks, waste mitigate escalating impact well-being.

Язык: Английский

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Unseen Threats: The Long‐term Impact of PET‐Microplastics on Development of Male Reproductive Over a Lifetime

Advanced Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 13, 2025

Abstract The physical abrasion of plastics from simple everyday entered the food chain, with associated risks recently emphasized. Although many studies have reported adverse effects microplastics (MPs) on human, reproductive implications continuous exposure to physically abraded polyethylene terephthalate (PET)‐MPs remain unexplored. Ingestion PET‐MPs (size range: 50–100 µm) in mice 5 34 weeks age at an annual intake relevant dose MPs (5 mg week −1 ) significantly impaired male function. Reductions seminiferous tubule diameter and epithelial height are observed ( p < 0.0001), 32.2% decrease Leydig cells 24.3% reduction testosterone levels 0.05). epididymis shows marked deterioration all regions, total sperm concentration reduce 17.0 × 10⁶ 5.3 0.01) motility. Transcriptome analysis demonstrates downregulation genes related gonadotropin‐releasing hormone secretion, biosynthesis, Meiosin gene, which is for crucial spermatogenesis. Continuous ingestion plastic bottles adversely affected testicular epididymal functions, leading hormonal imbalances abnormal production. These findings raise concerns about impact commonly used development, highlighting potential future generations.

Язык: Английский

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Visible-light driven photodegradation of low-density polyethylene (LDPE) using BiOCl–ZrO2 nanocomposite: A sustainable strategy for mitigating plastic pollution

Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 38, С. 101149 - 101149

Опубликована: Апрель 18, 2024

Язык: Английский

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Nanoplastics and Neurodegeneration in ALS

Brain Sciences, Год журнала: 2024, Номер 14(5), С. 471 - 471

Опубликована: Май 7, 2024

Plastic production, which exceeds one million tons per year, is of global concern. The constituent low-density polymers enable spread over large distances and micro/nano particles (MNPLs) induce organ toxicity via digestion, inhalation, skin contact. Particles have been documented in all human tissues including breast milk. MNPLs, especially weathered particles, can breach the blood–brain barrier, inducing neurotoxicity. This has non-human species, human-induced pluripotent stem cell lines. Within brain, MNPLs initiate an inflammatory response with pro-inflammatory cytokine oxidative stress generation reactive oxygen mitochondrial dysfunction. Glutamate GABA neurotransmitter dysfunction also ensues alteration excitatory/inhibitory balance favor reduced inhibition resultant neuro-excitation. Inflammation cortical hyperexcitability are key abnormalities involved pathogenic cascade amyotrophic lateral sclerosis (ALS) intricately related to mislocalization aggregation TDP-43, a hallmark ALS. Water many foods contain humans, ingestion main form exposure. Digestion plastics within gut alter their properties, rendering them more toxic, they cause microbiome dysbiosis dysfunctional gut–brain axis. recognized as trigger and/or aggravating factor for ALS associated long (years or decades) preclinical period neonates infants exposed through milk, milk substitutes, toys. endangers time intense neurogenesis establishment neuronal circuitry, setting stage development neurodegeneration later life. MNPL neurotoxicity should be considered yet unrecognized risk diseases.

Язык: Английский

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Drosophila melanogaster as a tractable eco-environmental model to unravel the toxicity of micro- and nanoplastics

Environment International, Год журнала: 2024, Номер 192, С. 109012 - 109012

Опубликована: Сен. 17, 2024

Язык: Английский

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Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies

Reproductive Biology and Endocrinology, Год журнала: 2024, Номер 22(1)

Опубликована: Ноя. 11, 2024

The female reproductive system can face serious disorders and show abnormalities under the influence of environmental pollutants. Microplastics (MPs) nanoplastics (NPs) as emerging pollutants, by affecting different components this system, may make fertility a challenge. Animal studies have demonstrated that exposure to these substances weakens function ovaries causes decrease in ovarian reserve capacity. Also, continuous micro/nano plastics (MNPs) leads increased levels reactive oxygen species, induction oxidative stress, inflammatory responses, apoptosis granulosa cells, reduction number follicles. Furthermore, interfering with hypothalamic-pituitary-ovarian axis, particles disturb normal androgens endocrine balance delay growth gonads. Exposure MNPs accelerate carcinogenesis humans animal models. determined accumulate placenta, causing metabolic changes, disrupting development fetus, endangering health future generations. In humans, presence micro/nanoplastics placenta tissue, infant feces, breast milk has been reported. These directly affect mother increasing risk premature birth other pregnancy complications. This review aims outline hazardous effects on fetal discuss results experiments human research focusing cellular molecular pathways.

Язык: Английский

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Maternal exposure to polystyrene nanoplastics during gestation and lactation caused fertility decline in female mouse offspring

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 289, С. 117632 - 117632

Опубликована: Янв. 1, 2025

The impact of micro/nano plastics (MPs/NPs) on human health is a significant area research. Studies the effects maternal exposure to microplastics (MPs) fertility in offspring have been conducted, but damage caused by nanoplastics (NPs) remains ambiguous. In this study, pregnant Kunming mice were exposed 30 mg/kg/day PS-NPs from 0.5 gestation day (GD) 21 days postpartum (dpp). Increased rates miscarriage and premature delivery observed, as well reduced litter size, indicating potential permanent reproductive injury group. Maternal impaired female offsprings. Decreased primordial increased growing follicles observed ovaries at 1 dpp 7 group, activation follicles. This likely due PS-NPs'induction AKT-FOXO3a signaling pathway downregulating AMPK phosphorylation level enhancing mTOR activity. Furthermore, reduction transzonal projections (TZPs) was noted adult RNA sequencing revealed that TZPs related genes may be linked CAMKIIβ, with corresponding downregulation expression levels. Overall, induced profound enduring functions offspring, raising critical alarms regarding multigenerational toxicity risks associated nanoplastic mammals.

Язык: Английский

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Study on Rapid Quantitative Detection of Soil MPs Based on Terahertz Time-Domain Spectroscopy

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 31, 2025

The presence of microplastics (MPs) in agricultural soils substantially affects the growth, reproduction, feeding, survival, and immunity levels soil biota. Therefore, it is crucial to investigate fast, effective, accurate techniques for detection MPs. This work explores integration terahertz time-domain spectroscopy (THz-TDS) with machine learning algorithms develop a method classification First, THz spectral image data were preprocessed using moving average (MA). Subsequently, three models developed, including random forest (RF), linear discriminant analysis, support vector (SVM). Notably, SVM model had an F1 score 0.9817, demonstrating its ability rapidly classify MPs samples. Three regression models, namely, principal component (PCR), RF, least squares (LSSVM), developed polymers soils. Six feature extraction methods used extract relevant parts containing key information. results study showed that accuracies PCR, LSSVM greater than 83%. Among them, RF highest overall accuracy. PE-UVE-RF best performance Rc2, Rp2, root mean square error calibration, prediction values 0.9974, 0.9916, 0.1595, 0.2680, respectively. Furthermore, this gets better by hypothesis testing predicting real

Язык: Английский

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Exposure to microplastics during pregnancy and fetal liver function

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 294, С. 118099 - 118099

Опубликована: Апрель 1, 2025

Emerging evidence suggests that in-utero exposure to microplastics (MPs) may have physiological consequences for fetal development, yet human data remain limited. This study investigates the association between placental microplastic and umbilical liver enzyme levels as markers of hepatic function. A prospective cohort was conducted in Shenyang, China, including 1057 pregnant women. Placental quantification performed using LD-IR chemical imaging, targeting polyvinyl chloride (PVC), polypropylene (PP), polybutylene succinate (PBS). Umbilical cord blood collected at delivery, alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate (AST), gamma-glutamyl transferase (GGT) were analyzed biochemical assays. Associations assessed via multivariable regression models adjusting maternal socioeconomic confounders. Mixture effects examined Bayesian Kernel Machine Regression (BKMR) quantile g-computation (g-comp). detected most samples (PVC: 88.4 %, PP: 88.8 PBS: 89.1 %), with a median total MPs 12 particles per 10 g tissue (IQR: 8). Higher PVC significantly associated increased ALP (β = 28.07, 95 % CI: 6.65-49.49, p 0.01). PP correlated positively ALT 0.63, 0.01-1.25, 0.05) AST 3.42, 0.87-5.96, Both burden exhibited strong associations GGT elevation (p < analysis revealed significant overall on 30.04, 11.15-48.92, 0.01), 7.30, 4.33-10.27, 22.98, 7.49-38.46, showing suggestive positive trend. Our findings provide novel MP is altered levels, particularly ALP, AST, GGT, indicating potential impacts These results underscore need further investigation into underlying mechanisms long-term health implications prenatal exposure.

Язык: Английский

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Feasibility of Raman and FTIR spectroscopy for direct microplastic search in the human milk samples: Comparative qualitative study

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 296, С. 118159 - 118159

Опубликована: Апрель 11, 2025

Язык: Английский

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