The Pb tolerance initiated by LdZIP8 in Lymantria dispar larvae: An effective defense against heavy metal stress DOI

Yubin He,

Ying Wang,

Aoying Zhang

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 486, С. 137025 - 137025

Опубликована: Дек. 27, 2024

Язык: Английский

Cinnamaldehyde-Based ROS-Responsive Polymeric Gene Vectors for Efficient Gene Delivery and Tumor Cell Growth Inhibition DOI
Qinfang Zhang,

Rui-Mo Zhao,

Lei Yu

и другие.

Biomacromolecules, Год журнала: 2025, Номер unknown

Опубликована: Янв. 29, 2025

Reactive oxygen species (ROS)-sensitive polymers are extensively used in cancer therapies. However, the ROS levels tumor microenvironment often insufficient to trigger an adequate therapeutic response. Herein, we report a cinnamaldehyde (CA)-based ROS-responsive cationic polymer (PCA) and demonstrate its high efficiency gene delivery cell growth inhibition. CA could be released from via ROS-sensitive thioacetal bond by endogenous ROS. The successively induced more accumulation through GSH depletion, positive feedback helped PCA achieve self-accelerating degradation. Results proved that PCA/p53 complexes were efficient depleting GSH, upregulating levels, transfection. Besides, was also shown effective delivering p53. More importantly, significantly induce suppression synergistic effect of p53, providing valuable insights into design self-amplifying polymeric vectors.

Язык: Английский

Процитировано

0
Cd exposure confers β-cypermethrin tolerance in Lymantria dispar by activating the ROS/CnCC signaling pathway-mediated P450 detoxification DOI

Mingtao Tan,

Hong Jiang,

Rusong Chai

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 478, С. 135566 - 135566

Опубликована: Авг. 16, 2024

Язык: Английский

Процитировано

1
Susceptibility of Lymantria dispar to Beauveria bassiana under short-term Cd stress: humoral immunostimulation cannot offset cellular immunotoxicity DOI

Aoying Zhang,

Yaning Li,

Mingtao Tan

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 136037 - 136037

Опубликована: Окт. 5, 2024

Язык: Английский

Процитировано

0
The synergistic potential of polyethylene glycol 400 for the control of Hyphantria cunea larvae by Beauveria bassiana DOI

Hui-Bin Sun,

Fusen Yue,

Mingtao Tan

и другие.

Pesticide Biochemistry and Physiology, Год журнала: 2024, Номер 206, С. 106182 - 106182

Опубликована: Окт. 25, 2024

Язык: Английский

Процитировано

0
The Pb tolerance initiated by LdZIP8 in Lymantria dispar larvae: An effective defense against heavy metal stress DOI

Yubin He,

Ying Wang,

Aoying Zhang

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 486, С. 137025 - 137025

Опубликована: Дек. 27, 2024

Язык: Английский

Процитировано

0