Exceptional anti-fouling, self-cleaning and high-flux ZIF-8@polyacrylonitrile based nanofiber composite membrane via in situ growth of seaweed-like ZnIn2S4 for efficient separation of emulsified oily wastewater

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 137355 - 137355

Опубликована: Янв. 1, 2025

Язык: Английский

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Fabrication of novel purine nucleoside derivatives bearing a cinnamic acid moiety for controlling plant viral diseases: synthesis, anti‐tobacco mosaic virus activity, and mechanistic study

Pest Management Science, Год журнала: 2025, Номер unknown

Опубликована: Апрель 2, 2025

In recent years, many plant viral diseases have triggered global epidemics, posing an intractable threat to food safety and the economy. However, antiviral agents currently remain insufficient due their limited control effect photothermal instability. Consequently, development of alternatives with high efficiency eco-friendly manifestation is a matter great urgency importance. Herein, 34 purine nucleoside derivatives bearing cinnamic acid building block were constructed underwent evaluation anti-tobacco mosaic virus (anti-TMV) potency. Biological assays demonstrated that compound A14 displayed excellent curative activity half maximal effective concentration (EC50) 274.25 mg L-1, which surpassed reference ribavirin (783.54 L-1) ningnanmycin (283.26 L-1). The mechanism action was further investigated through fluorescence confocal microscopy, reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR), TMV self-assembly, molecular docking, titration, transmission electron microscopy. Outcomes indicated could prevent systemic biosynthesis in plants, addition blocking self-assembly via interacting TMV-coat protein. Our research efforts resulted verification as novel agent alternative, possessed dual function inhibiting process TMV, for controlling diseases. © 2025 Society Chemical Industry.

Язык: Английский

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Biochar loaded with nicotine-degrading bacteria works synergistically with native microorganisms to efficiently degrade nicotine

Environment International, Год журнала: 2025, Номер 201, С. 109550 - 109550

Опубликована: Май 22, 2025

Nicotine, a potential environmental pollutant that has raised increasing concerns, accumulates to significant levels in soils under long-term tobacco monoculture, posing substantial risks both local ecosystems and human health. Addressing this challenge, the screening utilization of nicotine-degrading bacteria have emerged as central remediation strategy. In study, we isolated from tobacco-cultivated subsequently immobilized them onto biochar optimize degradation efficiency. A systematic investigation was conducted examine synergistic effects underlying mechanisms biochar-bacteria complex. Notably, successfully Paenarthrobacter ureafaciens N21 (N21), bacterial strain capable degrading nicotine through pyridine pathway. When on (BN21), composite maintained robust capabilities culture media soil environments. Compared with free N21, BN21 demonstrated 1.4 times enhancement efficiency significantly improved colonization capacity by (P < 0.0001). Stability assessment tests further confirmed BN21's consistent performance diverse conditions. Integrated microbiomic metabolomic analyses revealed induced alterations microbial community structure metabolic profiles, while enhancing soil's resistance repeated disturbances. Importantly, facilitated interactions between indigenous microorganisms, collectively mediating decomposition coordinated pyrrolidine pathways. The novel discovery bacteria-loaded synergistically removal highlights biochar-microbe composites for targeted elimination. This approach shows promising prospects future applications ecological various organic contaminants, providing innovative perspectives developing microbiome-based green strategies.

Язык: Английский

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pH responsive NKMOF-based platform for targeted delivery of azoxystrobin with enhanced fungicidal efficacy and biosafety

Pesticide Biochemistry and Physiology, Год журнала: 2025, Номер unknown, С. 106479 - 106479

Опубликована: Май 1, 2025

Язык: Английский

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The synergistic effect of biosynthesized CuONPs and phage (ϕPB2) as a novel approach for controlling Ralstonia solanacearum

Chemical and Biological Technologies in Agriculture, Год журнала: 2024, Номер 11(1)

Опубликована: Авг. 3, 2024

As a vital soil-borne pathogenic bacterium, Ralstonia solanacearum can cause wilt disease in multiple Solanaceae plants. Several phages, such as ϕPB2, could infect R. acting potential biological control agent soil. In addition, some nanoparticles, especially copper preparation, also showed high toxicity on with low plant. However, whether they be administered combination and how effective are inhibiting the plant caused by is known very little. this work, characterization of CuONPs using scanning electron microscope, transmission X-ray photoelectron spectroscopy, Fourier transform infrared diffraction ascertained presence which were nanometer particle 83 nm. Then it was found that combined application phage (ϕPB2) superior to ϕPB2 or alone controlling tobacco bacterial wilt, (250 mg/mL) (106 PFU/mL) ratio being best, at 79.1%. The no obvious growth than like single ϕPB2. Furthermore, transcriptome changes analysis indicated allocation inhibit "biofilm formation", molecular function, processes, cellular components, metabolic process, so on. higher inhibition motility biofilm, better enhancement cell membrane permeability, protein leakage, MDA concentration, enzyme activity their respiratory chain dehydrogenase (ϕPB2). Transcriptomes supported addition enhanced influencing ABC transporters quorum sensing, biosynthetic processes solanacearum. total, our work not only proposed novel way increase bactericidal effect nanomaterials adding phage, but discovered influence, synergistic effects, mechanisms, useful design combat phytopathogenic bacteria complicated environment.

Язык: Английский

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Controllable morphology CoFe2O4/g-C3N4 pH-responsive nanoplatform for enhanced chemo-photodynamic synergistic cancer therapy

Diamond and Related Materials, Год журнала: 2024, Номер 151, С. 111757 - 111757

Опубликована: Ноя. 17, 2024

Язык: Английский

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