Effects of Exposure to Different Types of Metal–Organic Framework Nanoparticles on the Gut Microbiota and Liver Metabolism of Adult Zebrafish

ACS Nano, Год журнала: 2024, Номер unknown

Опубликована: Авг. 31, 2024

Metal–organic framework nanoparticles (MOF NPs) have received much attention for their potential use in nanopesticides. However, little is known about the health and environmental risks associated with these materials. In this study, toxicological responses of zebrafish exposed to five MOF NPs short long periods time were evaluated. The acute toxicity results showed that embryos adult was order Cu-MOF > ZIF-90 ZIF-8 Fe-MOF Zr-MOF. Histopathological analysis revealed ZIF-8, ZIF-90, caused liver swelling vacuolization zebrafish. cellular ultrastructure severely damaged mitochondrial structure intestinal epithelial cells cells. 16S rDNA sequencing data all significantly altered dominant microorganisms intestine. microbial markers inflammation, Proteobacteria (Aeromonas, Plesiomonas, Legionella), increased Fe-MOF, Zr-MOF, treatment groups. Metabolomics indicated levels inflammatory promoting factors (Leukotriene E4, 20-hydroxyeicosatetraenoic acid) arachidonic acid metabolism decreased, suppressing (8,9-epoxyeicosatrienoic increased. Metabolites related oxidative stress, such as glutamine, pyridoxamine, l-glutamic vitamin B6 other signaling pathways, reduced. Overall, suggest different had widely varying zebrafish, further should be paid real environment.

Язык: Английский

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Sodium-lignosulfonate-conjugated metal–organic frameworks as dual-stimulus-responsive carriers for improved pesticide targeting

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 141275 - 141275

Опубликована: Фев. 1, 2025

Язык: Английский

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Green synthesis of Ag/V2O5 and Ag/V2O5-curdlan nanocomposites from Sargassum latifolium extract for enhanced antimicrobial and antioxidant activities

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 301, С. 140472 - 140472

Опубликована: Янв. 30, 2025

Язык: Английский

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Carboxymethyl Cellulose Surface Modification Alleviates the Toxicity of Fe-MOFs to Rice and Improves Iron Absorption

Nanomaterials, Год журнала: 2025, Номер 15(5), С. 336 - 336

Опубликована: Фев. 21, 2025

Iron-based metal-organic frameworks (Fe-MOFs) are widely used for agricultural chemical delivery due to their high loading capacity, and they also have the potential provide essential iron plant growth. Therefore, hold significant promise applications. Evaluating biotoxicity of Fe-MOFs is crucial optimizing use in agriculture. In this study, we natural biomacromolecule carboxymethyl cellulose (CMC) encapsulate Fe-MOF NH2-MIL-101 (Fe) (MIL). Through hydroponic experiments, investigated biotoxic effects on rice before after CMC modification. The results show that accumulation dependent dose exposure concentration Fe-MOFs. modification (MIL@CMC) can reduce release rate Fe ions from aqueous solutions with different pH values (5 7). Furthermore, MIL@CMC treatment significantly increases absorption by both aboveground root parts rice. alleviated growth inhibition seedlings increased biomass under medium- high-exposure conditions. Specifically, roots, MIL induced a more intense oxidative stress response, activities related antioxidant enzymes (CAT, POD, SOD) MDA content. Our demonstrated encapsulation NH2-MIL-101(Fe) using effectively damage promoted uptake These findings suggest rational positive effect reducing phytotoxicity MOFs improving biosafety

Язык: Английский

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Chemodynamic Metal-Phenolic Nanopesticide Performs In Situ Hydrogen Peroxide Self-Supply against Plant Pathogens for Food Sustainability

ACS Sustainable Chemistry & Engineering, Год журнала: 2025, Номер unknown

Опубликована: Апрель 2, 2025

Язык: Английский

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Metal-organic frameworks-molecularly imprinted polymers (MOF-MIP): Synthesis, properties, and applications in detection and control of microorganisms

Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер 252, С. 114670 - 114670

Опубликована: Апрель 6, 2025

Язык: Английский

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Treatment with metal–organic frameworks (MOFs) elicits secondary metabolite accumulation in Aquilaria crassna (agarwood) callus culture

Discover Plants., Год журнала: 2025, Номер 2(1)

Опубликована: Апрель 8, 2025

Abstract Thymelaceaous trees are prized for accumulating fragrant resins composed of hundreds secondary metabolites in their woody tissues. Slow growth and increasing consumer demand have stretched natural sources agarwood to being endangered alternative production modes, including silviculture tissue culture, currently investigated. Dedifferentiated culture provides a means cell propagation independent environmental context. However, metabolite accumulation, as found resins, occurs largely response wounding. Here, we investigated the application metal-organic frameworks (MOFs) potential elicitors formation Aquilaria crassna culture. Callus cultures were exposed five commercially available MOFs (UiO-67, MOF-808, HKUST-1, ZIF-67, MOF-74) ethanol extracts analysed using GC-MS quantify accumulation MOF-exposed compared untreated cultures. Samples that either two Zr-based exhibited profiles similar each other, (trans-2-Carboxy-cyclo-hexyl)-acetic acid was reduced presence all MOFs, Cu-containing HKUST-1 MOF increased palmitic levels, ZIF-67 (at 20 mg/L) elicit highest with fragrance applications. These results demonstrate possibility eliciting from dedifferentiated tree may provide an sourcing specialty chemicals these plants.

Язык: Английский

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Nanoparticles as tools for enhancing plant resistance to biotic stress in the context of climate change

Physiologia Plantarum, Год журнала: 2025, Номер 177(2)

Опубликована: Март 1, 2025

In the face of climate change, agriculture is increasingly challenged by shifting dynamics biotic stresses, including intensified spread pests and pathogens. Traditional control methods, often reliant on chemical pesticides, are associated with environmental degradation potential health risks. Nanoparticles (NPs) present a promising, sustainable alternative for enhancing plant resistance to potentially revolutionizing agricultural practices. This mini-review explores mechanisms through which NP-based formulations (such as metal-based NPs, chitosan, silica) induce responses bolster defences against pathogens pests. By resilience without downsides conventional NPs could support more approach crop protection. review also highlights risks in expanding use agriculture, urging studies explore these technologies managing crops changing climate.

Язык: Английский

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Treatment with Metal-Organic Frameworks (MOFs) elicits secondary metabolite accumulation in Aquilaria crassna (Agarwood) callus culture

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Авг. 23, 2024

Abstract Thymelaceaous trees are prized for accumulating fragrant resins composed of hundreds secondary metabolites in their woody tissues. Slow growth and increasing consumer demand have stretched natural sources agarwood to being endangered alternative production modes, including silviculture tissue culture, currently investigated. Dedifferentiated culture provides a means cell propagation independent environmental context. However, metabolite accumulation, as found resins, occurs largely response wounding. Here, we investigated the application metal-organic frameworks (MOFs) potential elicitors formation Aquilaria crassna samples. Callus cultures were exposed five commercially available MOFs: UiO-67, MOF-808, HKUST-1, ZIF-67, MOF-74, ethanol extracts used quantify accumulation compared untreated cultures. Samples that Zr-based MOFs exhibited similar profiles, (trans-2-Carboxy-cyclo-hexyl)-acetic acid was reduced presence all MOFs, Cu-containing HKUST-1 MOF increased palmitic levels, MOF-808 ZIF-67 elicit highest with fragrance applications. These results demonstrate possibility eliciting from dedifferentiated tree may provide an sourcing specialty chemicals these plants.

Язык: Английский

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Invited Review Plant Class III acyl-CoA binding proteins can protect against necrotrophs: A review

Physiological and Molecular Plant Pathology, Год журнала: 2024, Номер unknown, С. 102459 - 102459

Опубликована: Окт. 1, 2024

Язык: Английский

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