Analytical Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 10, 2024
A
novel
self-powered
biosensor
has
been
developed
for
the
detection
of
chloramphenicol
(CAP)
based
on
difunctional
triple
helix
molecular
switch
(THMS)-mediated
DNA
walkers.
The
utilizes
CAP
aptamer
as
recognition
element,
a
walker
and
capacitor
dual
signal
amplification
strategies,
digital
multimeter
(DMM)
data
readout
equipment.
In
presence
target,
in
THMS
specifically
binds
with
to
release
transduction
probe
(STP)
opens
H1
hairpin
structure
biocathode
trigger
form
double-stranded
structure.
Then,
[Ru(NH
Environmental Science & Technology,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 27, 2025
Tetracyclines
(TCs)
are
widely
present
in
the
environment
with
extreme
toxicity,
low
concentrations,
coexistence
a
variety
of
pollutants,
and
similarity
their
individual
molecular
structures
toxicology.
These
challenges
make
it
difficult
to
analyze
monitor
TCs
as
class
molecules
simultaneously.
In
this
study,
broad-spectrum
aptamer
capable
recognizing
was
developed
by
artificially
editing
single-specific
aptamer.
Subsequently,
based
on
mathematical
proof
detection
TCs,
an
electrochemical
sensor
constructed
enable
simple
rapid
monitoring
high
sensitivity,
selectivity,
wide
range.
The
exhibits
range
0.01
1000
nM
limit
1.18
pM,
while
maintaining
excellent
selectivity
even
presence
interfering
substances
at
concentrations
up
100
times
test
concentration.
This
is
suitable
for
quantifying
overall
level
various
environmental
scenarios,
facilitating
study
transport
transformation
processes
systems.
Finally,
recognition
mechanism
elucidated,
which
makes
method
rational
universal,
will
help
future
researchers
obtain
aptamers
analysis
multiple
classes
pollutants.
