Assessing toxicological risk of nanoplastics contaminants in food and feed from ingestion pathway to human diseases
F1000Research,
Год журнала:
2025,
Номер
14, С. 284 - 284
Опубликована: Март 12, 2025
The
extensive
use
of
plastic
without
an
effective
management
system
is
linked
to
significant
environmental
pollution
issues.
The
fragmentation
various
types
waste
leads
the
formation
microplastics
(MPs)
and
nanoplastics
(NPs).
NPs,
measuring
less
than
0.1
μm
pose
a
latent
danger
human
food
chain
caused
by
ability
traverse
biological
membranes
MPs,
potentially
leading
chronic
diseases.
widespread
distribution
NPs
across
diverse
matrices
their
subsequent
infiltration
into
feed
chains
precipitates
emerging
health
concerns.
contaminate
production
systems
leach
from
packaging,
infiltrating
organisms
at
trophic
levels.
Seafood,
processed
foods,
drinking
water
serve
as
vectors
for
absorption
accumulation
in
tissues.
pervasive
contamination
pathway
poses
substantial
risks
through
multiple
exposure
routes,
primarily
ingestion.
It
can
lead
cytotoxicity,
inflammation,
genotoxicity,
apoptosis.
This
review
summarizes
implications
that
triggers
diseases
such
inflammatory
bowel
disease
(IBD),
kidney
dysfunction,
liver
disease,
heart
problems,
brain
disorders,
reproductive
issues,
cancer.
Currently,
no
established
method
exists
treat
humans
may
have
already
ingested.
Hence,
it
urgent
mitigate
harmful
effects
development
implementation
innovative,
efficient,
sustainable
decontamination
strategies.
discussion
highlights
several
advanced
remediation
techniques
effectively
reduce
toxicity
systems,
thus
mitigating
associated
risks.
Язык: Английский