The role of green synthesis metal and metal oxide nanoparticles in oral cancer therapy: a review DOI

Songlin Zhou,

Yutao Qin,

Anle Lei

и другие.

Journal of drug targeting, Год журнала: 2025, Номер unknown, С. 1 - 39

Опубликована: Янв. 30, 2025

There are 275,000 new cases of oral cancer (OC) per year, making it the sixth most common in world. Severe adverse effects, including loss function, deformity, and systemic toxicity, familiar with traditional therapies such as radiation, chemotherapy, surgery; due to their unique properties, nanoparticles (NPs) have emerged a superior alternative over chemo/radiotherapy surgery targeting capability, bioavailability, compatibility, high solubility. Due metallic NPs garnered significant attention OC control. In addition fact that metal may be harmful human cells, reactive chemicals used make them pose same risk, which limits use medicine. Green synthesis (GS) is novel strategy uses biological materials like yeast, bacteria, fungi, plant extracts. Compared more chemical processes, these environmentally benign manageable for living organisms. This article summarizes GS made metals oxides anticancer effects on OC. The method's potential benefits drawbacks advancing NPs' shaping therapy's future were also discussed.

Язык: Английский

Biosynthesis of Nanoparticles from Various Biological Sources and Its Biomedical Applications DOI Creative Commons
Gopalu Karunakaran, Kattakgoundar Govindaraj Sudha, Saheb Ali

и другие.

Molecules, Год журнала: 2023, Номер 28(11), С. 4527 - 4527

Опубликована: Июнь 2, 2023

In the last few decades, broad scope of nanomedicine has played an important role in global healthcare industry. Biological acquisition methods to obtain nanoparticles (NPs) offer a low-cost, non-toxic, and environmentally friendly approach. This review shows recent data about several for procuring exhaustive elucidation biological agents such as plants, algae, bacteria, fungi, actinomycete, yeast. When compared physical, chemical, approaches obtaining nanoparticles, approach significant advantages non-toxicity environmental friendliness, which support their use therapeutic applications. The bio-mediated, procured not only help researchers but also manipulate particles provide health safety. addition, we examined biomedical applications antibacterial, antifungal, antiviral, anti-inflammatory, antidiabetic, antioxidant, other medical highlights findings current research on bio-mediated novel NPs scrutinizes various proposed describe them. synthesis from plant extracts advantages, including bioavailability, low cost. Researchers have sequenced analysis biochemical mechanisms enzyme reactions well determination bioactive compounds mediated by nanoparticle acquisition. is primarily concerned with collating variety disciplines that frequently provides new clarifications serious problems.

Язык: Английский

Процитировано

80
ZnO based 0–3D diverse nano-architectures, films and coatings for biomedical applications DOI
Suresh Babu Naidu Krishna, Jaroon Jakmunee, Yogendra Kumar Mishra

и другие.

Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(12), С. 2950 - 2984

Опубликована: Янв. 1, 2024

This review highlights the design and engineering of ZnO based 0–3D nano-architectures, thin films coatings with tunable characteristics for multifunctional biomedical applications.

Язык: Английский

Процитировано

23
Influence of Physicochemical Properties of Iron Oxide Nanoparticles on Their Antibacterial Activity DOI Creative Commons
Kishan Nandi Shoudho, Shihab Uddin, Md. Mahamudul Hasan Rumon

и другие.

ACS Omega, Год журнала: 2024, Номер 9(31), С. 33303 - 33334

Опубликована: Июль 25, 2024

The increasing occurrence of infectious diseases caused by antimicrobial resistance organisms urged the necessity to develop more potent, selective, and safe agents. unique magnetic tunable properties iron oxide nanoparticles (IONPs) make them a promising candidate for different theragnostic applications, including Though IONPs act as nonspecific agent, their activities are directly or indirectly linked with synthesis methods, synthesizing precursors, size, shapes, concentration, surface modifications. Alteration these parameters could accelerate decelerate production reactive oxygen species (ROS). An increase in ROS role disrupts bacterial cell walls, membranes, alters major biomolecules (e.g., lipids, proteins, nucleic acids), affects metabolic processes Krebs cycle, fatty acid synthesis, ATP glycolysis, mitophagy). In this review, we will investigate antibacterial activity bare surface-modified influence physiochemical on activity. Additionally, report potential mechanism IONPs' action driving

Язык: Английский

Процитировано

21
Effect of precursor concentration on the bandgap energy and particles size for green synthesis of hematite α-Fe2O3 nanoparticles by the aqueous extract of Moltkia ciliata and evaluation of the antibacterial activity DOI

Soumaia Chihi,

Abderrhmane Bouafia, Souhaila Meneceur

и другие.

Biomass Conversion and Biorefinery, Год журнала: 2023, Номер unknown

Опубликована: Авг. 26, 2023

Язык: Английский

Процитировано

27
Breaking Barriers in Eco-Friendly Synthesis of Plant-Mediated Metal/Metal Oxide/Bimetallic Nanoparticles: Antibacterial, Anticancer, Mechanism Elucidation, and Versatile Utilizations DOI Open Access
Swati Dubey, Tarun Virmani, Shiv Kumar Yadav

и другие.

Journal of Nanomaterials, Год журнала: 2024, Номер 2024, С. 1 - 48

Опубликована: Апрель 12, 2024

Nanotechnology has emerged as a promising field in pharmaceutical research, involving producing unique nanoscale materials with sizes up to 100 nm via physiochemical and biological approaches. Nowadays more emphasis been given eco-friendly techniques for developing nanomaterials enhance their applications minimize health environmental risks. With the help of green nanotechnology, wide range metal, metal oxide, bimetallic nanoparticles distinct chemical compositions, sizes, morphologies have manufactured which are safe, economical, environment friendly. Due biocompatibility vast potential biomedical (antibacterial, anticancer, antiviral, analgesic, anticoagulant, biofilm inhibitory activity) other fields such (nanofertilizers, fermentative, food, bioethanol production, construction field), garnered significant interest worldwide. The precursors combined natural extracts plants, algae, fungi, bacteria get potent novel Ag, Au, Co, Cu, Fe, Zr, Zn, Ni, Pt, Mg, Ti, Pd, Cd, Bi2O3, CeO2, Co3O4, CoFe2O4, CuO, Fe2O3, MgO, NiO, TiO2, ZnO, ZrO2, Ag-Au, Ag-Cr, Ag-Cu, Ag-Zn, Ag-CeO2, Ag-CuO, Ag-SeO2, Ag-TiO2, Ag-ZnO, Cu-Ag, Cu-Mg, Cu-Ni, Pd-Pt, Pt-Ag, ZnO-CuO, ZnO-SeO, ZnO-Se, Se-Zr, Co-Bi2O3. These plant-mediated possess excellent antibacterial anticancer activity when tested against several microorganisms cancer cell lines. Plants contain essential phytoconstituents (polyphenols, flavonoids, terpenoids, glycosides, alkaloids, etc.) compared sources (bacteria, algae) higher concentration that play vital role development because these plant-phytoconstituents act reducing, stabilizing, capping agent helps nanoparticles. After concluding all findings, this review designed first time way it imparts satisfactory knowledge about together, along mechanisms. Additionally, provides information characterization (UV–vis, FT-IR, DLS, XRD, SEM, TEM, BET, AFM) employed nanoparticles, applications, industries. Hence, various types versatile application diverse is not covered pieces literature.

Язык: Английский

Процитировано

16
Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review DOI Creative Commons
Shahbaz Ahmad, Shujaat Ahmad, Shujat Ali

и другие.

International Journal of Nanomedicine, Год журнала: 2024, Номер Volume 19, С. 3187 - 3215

Опубликована: Апрель 1, 2024

Abstract: Green synthesis of silver (Ag) and gold (Au) nanoparticles (NPs) has acquired huge popularity owing to their potential applications in various fields. A large number research articles exist the literature describing green Ag Au NPs for biomedical applications. However, these findings are scattered, making it time-consuming researchers locate promising advancements unexplored Unlike other review articles, this systematic study not only highlights recent but also explores The article discusses approaches highlighting emerging developments novel strategies. Then, reviews important synthesized by critically evaluating expected advantages. To expose future direction field, describes NPs. Finally, discuss challenges limitations This will serve as a valuable reference researchers, working on Keywords: nanoparticles, environmental-friendly, applications, potentials

Язык: Английский

Процитировано

15
Methylene Blue Removal by Copper Oxide Nanoparticles Obtained from Green Synthesis of Melia azedarach: Kinetic and Isotherm Studies DOI Creative Commons
Wafa K. Essa

Chemistry, Год журнала: 2024, Номер 6(1), С. 249 - 263

Опубликована: Фев. 19, 2024

In this study, Melia azedarach fruit extract was used as a reducing agent and copper chloride dihydrate (CuCl2·2H2O) precursor in the synthesis of oxide nanoparticles (CuO NPs). The UV–visible spectrum showed characteristic absorption peak CuO NPs at 350 nm. surface properties adsorbent were analyzed through various techniques, indicating successful formation NPs. impacts several factors, including initial pH (4 to 8), dose (0.01–0.05 g), dye concentration (10–50 mg·L−1), contact times ranging from 5 120 min, examined batch adsorption studies. Based on experimental results, Langmuir isotherm is well-fitted, MB monolayer capping with 26.738 mg·g−1 maximum capacity Qm value. For pseudo-second-order kinetic model, calculated values (qe) exhibited good agreement.

Язык: Английский

Процитировано

13
Green synthesis of silver and gold nanoparticles using quercetin extracted from Arctium lappa by HPLC, Characterization and Estimation of antioxidant activity DOI Creative Commons

Mahmood Zaki Lafta,

Rafah Razooq Hameed Al-Samarrai, ‪Mohamed Bouaziz

и другие.

Results in Chemistry, Год журнала: 2025, Номер 13, С. 102028 - 102028

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

2
Synthesis of iron oxide nanoparticles using orange fruit peel extract for efficient remediation of dye pollutant in wastewater DOI

N. V. Sithara,

Devaraj Bharathi, Jintae Lee

и другие.

Environmental Geochemistry and Health, Год журнала: 2024, Номер 46(2)

Опубликована: Янв. 16, 2024

Язык: Английский

Процитировано

8
Phyto-Mediated Green Synthesis of Silver Nanoparticles Using an Aqueous Leaf Extract of Momordica cymbalaria: Antioxidant, Cytotoxic, Antibacterial, and Photocatalytic Properties DOI Creative Commons
Madasamy Sundar, Gopalan Rajagopal,

A. Nivetha

и другие.

Separations, Год журнала: 2024, Номер 11(2), С. 61 - 61

Опубликована: Фев. 17, 2024

In this study, we biosynthesized the stable silver nanoparticles (AgNPs) from Momordica cymbalaria leaves to evaluate their antioxidant, antibacterial, cytotoxic, and photocatalytic properties. Initially, screened bioactive compounds M. extract using GC-MS. The biosynthesis of Mc-AgNPs was confirmed instruments, such as UV-visible spectroscopy FT-IR, XRD, SEM with EDX, HR-TEM analyses. spectrum indicated absorbance at 425 nm. crystallite size cymbalaria-stabilized determined be 20.14 morphology synthesized were via SEM-EDX analyses, a range 16 22 exhibited yield 60%. demonstrated strong antioxidant properties prominent antibacterial activity against human pathogenic bacteria. cytotoxicity study revealed that effective MCF-7 cells in dose-dependent manner. recognized bioactivities confirm act catalysts oxidation serve potent anticancer, agents.

Язык: Английский

Процитировано

8