Green Synthesis and Biomedical Potential of L-Ascorbic Acid-Stabilized Copper Sulfide Nanoparticles as Antibacterial and Antioxidant Agents DOI
Shafiul Haque, Saba Siddiqui, Abdullah Mashraqi

и другие.

Drug Development and Industrial Pharmacy, Год журнала: 2025, Номер unknown, С. 1 - 14

Опубликована: Апрель 1, 2025

Copper sulfide nanoparticles (CuS NPs) are promising materials for a variety of biomedical applications, particularly as antimicrobial and antioxidant agents. The main objective this study was to synthesize CuS NPs evaluate their efficiency an antibacterial agent. were prepared in single step process using L-ascorbic acid the stabilizing Systematic structural morphological characterization performed standard techniques X-ray diffraction (XRD), Fourier-transform infrared (FT-IR) spectroscopy, scanning (SEM) transmission electron microscopy (TEM). Further, agar well disk-diffusion method applied determination sensitivity minimum inhibitory concentration (MIC) against multiple pathogenic bacterial strains. potential evaluated by performing total reduction capability, nitric oxide (NO) 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activities at doses, with L-ascorbate reference. results indicated amorphous nature size range 8.17 9.63 nm. FI-IR confirmed presence several bioactive functional groups required copper ions. Additionally, our showed robust species such Escherichia coli Staphylococcus aureus) diffusion assays, zone inhibition values ranging between 21 23 mm. also potent dose-dependent activity. cost- time-efficient manner have excellent properties be different applications.

Язык: Английский

Green Synthesis and Biomedical Potential of L-Ascorbic Acid-Stabilized Copper Sulfide Nanoparticles as Antibacterial and Antioxidant Agents DOI
Shafiul Haque, Saba Siddiqui, Abdullah Mashraqi

и другие.

Drug Development and Industrial Pharmacy, Год журнала: 2025, Номер unknown, С. 1 - 14

Опубликована: Апрель 1, 2025

Copper sulfide nanoparticles (CuS NPs) are promising materials for a variety of biomedical applications, particularly as antimicrobial and antioxidant agents. The main objective this study was to synthesize CuS NPs evaluate their efficiency an antibacterial agent. were prepared in single step process using L-ascorbic acid the stabilizing Systematic structural morphological characterization performed standard techniques X-ray diffraction (XRD), Fourier-transform infrared (FT-IR) spectroscopy, scanning (SEM) transmission electron microscopy (TEM). Further, agar well disk-diffusion method applied determination sensitivity minimum inhibitory concentration (MIC) against multiple pathogenic bacterial strains. potential evaluated by performing total reduction capability, nitric oxide (NO) 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activities at doses, with L-ascorbate reference. results indicated amorphous nature size range 8.17 9.63 nm. FI-IR confirmed presence several bioactive functional groups required copper ions. Additionally, our showed robust species such Escherichia coli Staphylococcus aureus) diffusion assays, zone inhibition values ranging between 21 23 mm. also potent dose-dependent activity. cost- time-efficient manner have excellent properties be different applications.

Язык: Английский

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