Bacterial Infections, Trends, and Resistance Patterns in the Time of the COVID-19 Pandemic in Romania—A Systematic Review
Antibiotics,
Год журнала:
2024,
Номер
13(12), С. 1219 - 1219
Опубликована: Дек. 14, 2024
Background:
The
COVID-19
pandemic
has
intensified
concerns
over
bacterial
infections
and
antimicrobial
resistance,
particularly
in
Romania.
This
systematic
review
explores
infection
patterns
resistance
during
the
to
address
critical
gaps
knowledge.
Methods:
A
review,
following
PRISMA
guidelines,
was
conducted
using
databases
such
as
PubMed
Scopus,
focusing
on
studies
of
from
2020
2022.
Articles
Romanian
patients
were
analyzed
for
demographic
data,
trends,
profiles.
Results:
total
87
included,
detailing
20,000
cases
infections.
found
that
Gram-negative
bacteria,
Escherichia
coli
Klebsiella
pneumoniae,
most
frequently
identified
pathogens,
alongside
Gram-positive
Staphylococcus
aureus
Enterococcus
spp.
Multidrug
(MDR)
noted
24%
reported
strains,
with
common
carbapenems
cephalosporins.
Conclusions:
amplified
complexity
managing
infections,
critically
ill
patients.
rise
MDR
bacteria
underscores
need
stringent
stewardship
control
measures.
Continuous
monitoring
trends
profiles
will
be
essential
improve
treatment
strategies
post-pandemic
healthcare
settings.
Язык: Английский
Correlations of Multidrug Resistance in <em>Acinetobacter baumannii </em>and <em>Klebsiella pneumoniae </em>with Long-Term Aminoglycoside Consumption and Resistance Data
Bence Sajerli,
Klára Makai,
Ágnes Sarkadi-Nagy
и другие.
Опубликована: Июль 12, 2024
Multidrug
resistant
bacteria
pose
a
significant
threat
to
global
health,
particularly
in
healthcare
settings.
This
study
aimed
explore
the
potential
of
aminoglycoside
consumption
and
resistance
data
correlate
with
multidrug
Acinetobacter
baumannii
Klebsiella
pneumoniae.
Data
on
antibiotic
indices
(ARI)
were
collected
from
2010
2023.
Descriptive
statistics
Pearson
correlation
analyzes
performed
examine
both
immediate
delayed
(one-year
delay)
correlations
between
use
(amikacin,
tobramycin,
gentamicin)
patterns.
The
results
indicated
that
amikacin
was
consistently
high
correlated
bacterial
species.
Tobramycin
gentamicin
showed
variable
patterns,
negative
some
cases.
Delayed
effect
analysis
revealed
tobramycin
had
slight
positive
impact
A.
baumannii,
while
associated
reduction
resistance.
In
K.
pneumoniae,
strong
resistance,
weaker
associations.
These
findings
highlight
complex
species-specific
relationships
development,
emphasizing
need
for
customized
management
strategies
account
effects
use.
Язык: Английский