Microstructure development of Ti scaffold by laser powder bed fusion with chemical polishing and its mechanical properties, biocompatibility

Biosurface and Biotribology, Год журнала: 2024, Номер 10(2), С. 52 - 62

Опубликована: Май 16, 2024

Abstract Titanium (Ti) dental scaffolds are widely used in prosthetics due to their excellent mechanical properties and biocompatibility. However, conventional Ti manufactured through machining often do not fit perfectly with the bone defect site. Laser powder bed fusion (LPBF) technology enables personalised manufacturing of custom‐made scaffolds. A scaffold was prepared using LPBF its surface roughness improved chemical polishing. To enhance roughness, a nitric acid mixed solution specific composition HF: HNO 3 :C H 6 O = 2:2:3 used. The polishing mechanism investigated by adjusting F/Ti ratio control formation dissolution oxide film. As result, after exhibited smooth flat appearance compared part, reduced (Ra) 1.23 ± 0.19 μm. also demonstrated favourable properties, bending strength 335.18 33.62 MPa stiffness 2.13 0.21 GPa. Furthermore, vitro cell tests confirmed biocompatibility scaffold. authors present feasible strategy for further clinical application scaffolds, offering enhanced addressing limitations methods.

Язык: Английский

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Polyphenols-based intelligent oral barrier membranes for periodontal bone defect reconstruction

Regenerative Biomaterials, Год журнала: 2024, Номер 11

Опубликована: Янв. 1, 2024

Abstract Periodontitis-induced periodontal bone defects significantly impact patients’ daily lives. The guided tissue regeneration and techniques, which are based on barrier membranes, have brought hope for the of defects. However, traditional membranes lack antimicrobial properties cannot effectively regulate complex oxidative stress microenvironment in defect areas, leading to unsatisfactory outcomes promoting regeneration. To address these issues, our study selected collagen membrane as substrate material synthesized a novel (PO/4-BPBA/Mino@COL, PBMC) with an intelligent coating through simple layer-by-layer assembly method, incorporating reactive oxygen species (ROS)-scavenging components, commercial dual-functional linkers building blocks. Experimental results indicated that PBMC exhibited good degradability, hydrophilicity ROS-responsiveness, allowing slow controlled release drugs. outstanding antibacterial, antioxidant biocompatibility contributed resistance pathogen infection regulation balance, while enhancing migration osteogenic differentiation human ligament stem cells. Finally, using rat model, therapeutic effect under conditions was confirmed. In summary, designed this significant potential clinical application provide reference design future regenerative functional materials.

Язык: Английский

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A novel iron/zinc phosphate layered composite coating on Zn-0.5Li alloy for guided bone regeneration membrane applications

Journal of Materials Research and Technology, Год журнала: 2024, Номер unknown

Опубликована: Дек. 1, 2024

Язык: Английский

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Preparation and investigation of Zn foil/poly(lactic acid) composite films for guiding bone regeneration

Surface and Coatings Technology, Год журнала: 2024, Номер 494, С. 131537 - 131537

Опубликована: Окт. 1, 2024

Язык: Английский

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Optimal submicron roughness for balancing degradation behavior, immune modulation, and microbial adhesion on zinc-based barrier membranes

Biomaterials Advances, Год журнала: 2024, Номер 169, С. 214146 - 214146

Опубликована: Дек. 10, 2024

Язык: Английский

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